NIH-funded research NIH-funded research

WeCare: a mental health and HIV medication adherence program for high-risk men in resource-poor settings

Official title: Addressing mental health and HIV medication adherence among high-risk men in a resource-limited setting

Funded at Emory University · NIH-11399084 · Data updated 2026-11-12

A patient-friendly approach called WeCare is being tested to help high-risk men manage stress and depression while sticking to HIV PrEP and ART in low-resource settings.

More Mental Health research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmory University
NIH-funded
Lab location1 site (Atlanta, United States)
Project startAugust 19, 2024
Project endJuly 31, 2027
Funding year2026
Award (this year)$72,449
NIH project number5R34MH135806-03
Project IDNIH-11399084 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates include high-risk men in resource-limited settings who are on PrEP or ART and experience stress, depression, or adherence challenges.

Less likely to help

Individuals without HIV risk or current PrEP/ART use, or those not facing mental health or adherence barriers, may not benefit.

What this research studies

WeCare is a new, integrated program designed to support men living with or at risk for HIV by addressing mental health and medication adherence together. The project will first gather insights from the target population to shape the intervention, then pilot a manual and implementation plan, and finally compare WeCare to enhanced standard care in a small randomized trial. Participants will be followed at baseline, 3 months, and 6 months to measure changes in mental health and actual medication adherence using biological tests and self-reports. The goal is to create a scalable, stigma-aware approach that helps people stay on PrEP and ART more consistently.

Why it matters

Potential benefit: If successful, WeCare could improve mental health and HIV treatment adherence for men in tough settings, potentially reducing HIV transmission and improving health outcomes.

How similar studies have gone: Similar integrated adherence and mental health approaches have shown promise in pilot settings, but this exact program is novel in its framing and population.

Where this research is happening

  • Emory University
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Operario, Don — Emory University
  • Study coordinator: Operario, Don

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.