NIH-funded research R21 grant

Medication support for children after a stem cell transplant

Official title: MedMemos: A Program to Promote Medication Adherence in Pediatric Hematopoeitic Stem Cell Transplantation

Funded at Research Inst Nationwide Children's Hosp · NIH-11374322 · Data updated 2026-11-12

This program gives caregivers short, tailored lessons and a Medication Management Kit to help families keep up with complex outpatient medicines after a child's allogeneic stem cell transplant.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionResearch Inst Nationwide Children's Hosp
NIH-funded
Lab location1 site (Columbus, United States)
Project startMay 1, 2026
Project endApril 30, 2028
Funding year2026
Award (this year)$406,258
NIH project number1R21CA309321-01A1
Project IDNIH-11374322 on NIH RePORTER

Who could benefit from this research

Could help

Children receiving an allogeneic hematopoietic stem cell transplant and their primary caregivers—especially those managing the transition from hospital to home—are the intended participants.

Less likely to help

Families without a primary caregiver responsible for medications, patients not undergoing allogeneic transplant, or those unable to participate in the inpatient and outpatient sessions are unlikely to benefit from this program.

What this research studies

As a caregiver of a child who had a stem cell transplant, I would get four brief sessions—two while my child is in the hospital and two after we go home—plus short, personalized education videos and a Medication Management Kit. The team will deliver the program to small groups of caregiver–patient pairs, ask for our feedback, and refine the content and timing based on what works for families and providers. The project focuses on practical strategies to overcome common barriers like confusing schedules, changing prescriptions, and caregiver stress. If helpful, the program will move on to a next phase to show whether these changes lead to better medication-taking habits.

Why it matters

Potential benefit: This could help families keep children on critical medicines more consistently and lower the risk of serious complications like graft-versus-host disease and rehospitalization.

How similar studies have gone: Caregiver-focused adherence efforts have shown promise in other pediatric chronic conditions, but this specific tailored MedMemos approach for pediatric allogeneic transplant is new.

Where this research is happening

  • Research Inst Nationwide Children's Hosp
    Columbus, United States
    Active

Researchers

  • Principal investigator: Pai, Ahna Luise — Research Inst Nationwide Children's Hosp
  • Study coordinator: Pai, Ahna Luise

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.