Support program for young adults recovering from opioid use disorder
Official title: The Youth Opioid Recovery Support (YORS) Intervention: An Assertive Community Treatment Model for Improving Medication Adherence in Young Adults With Opioid Use Disorder
Run by Potomac Health Foundations · NCT04173416 · Data updated 2026-11-12
This study is testing a new support program to help young adults aged 18-28 with opioid use disorder stick to their treatment and feel more engaged in their recovery.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 28 Years |
| Sex | All |
| Enrollment | 150 (estimated) |
| Sponsor | Potomac Health Foundations Academic / other |
| Locations | 1 site (Baltimore, Maryland) |
| Status | Recruiting |
| Started | February 17, 2020 |
| Main results expected | August 31, 2026 |
| Study ends | August 31, 2026 |
| Registry record updated | September 24, 2025 |
| Trial ID | NCT04173416 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are young adults aged 18-28 diagnosed with opioid use disorder who are willing to engage in treatment with extended release naltrexone or buprenorphine.
✕Probably not a fit
Patients with psychiatric or medical instability or those living more than 75 miles from the treatment center may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The Youth Opioid Recovery Support (YORS) intervention aims to improve medication adherence and treatment engagement among young adults aged 18-28 with opioid use disorder (OUD). This innovative model includes home delivery of medication, family involvement in treatment planning, assertive outreach via text and social media, and contingency management to incentivize adherence. The study will refine the YORS approach through stakeholder input and pilot testing, followed by a randomized controlled trial to evaluate its efficacy. The goal is to develop effective strategies to address the opioid crisis in this vulnerable population.
Why it matters
Potential benefit: If successful, this intervention could significantly enhance treatment adherence and outcomes for young adults struggling with opioid use disorder.
How similar studies have gone: Preliminary results from a small pilot randomized clinical trial of the YORS model have shown promising outcomes, indicating potential for success in larger studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-28 * OUD diagnosis * Willing (intending) to receive treatment with XR-NTX or XR-BUP under the care of a MTC physician/nurse practitioner * Willingness to designate family member (or other suitable treatment significant other) for treatment involvement (i.e., a treatment significant other; TSO) Exclusion Criteria: * Psychiatric or medical instability (e.g., suicidality, psychosis, Sickle Cell disease with frequent crises) that would preclude participation in the trial * Living situation (location greater than 75 miles from the center, homelessness) that would preclude participation in the trial
Where it's running
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Mountain Manor Treatment Center
Baltimore, Maryland, United States Recruiting
Study contacts
- Principal investigator: Marc Fishman, MD — Maryland Treatment Centers, Inc.
- Study coordinator: Marc Fishman, MD
- Email: mjfishman@comcast.net
- Phone: 410-233-1400
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.