Support program for young adults recovering from opioid use disorder

The Youth Opioid Recovery Support (YORS) Intervention: An Assertive Community Treatment Model for Improving Medication Adherence in Young Adults With Opioid Use Disorder

Not applicable Interventional Potomac Health Foundations · NCT04173416

This study is testing a new support program to help young adults aged 18-28 with opioid use disorder stick to their treatment and feel more engaged in their recovery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment150 (estimated)
Ages18 Years to 28 Years
SexAll
SponsorPotomac Health Foundations Academic / other
Locations1 site (Baltimore, Maryland)
Trial IDNCT04173416 on ClinicalTrials.gov

What this trial studies

The Youth Opioid Recovery Support (YORS) intervention aims to improve medication adherence and treatment engagement among young adults aged 18-28 with opioid use disorder (OUD). This innovative model includes home delivery of medication, family involvement in treatment planning, assertive outreach via text and social media, and contingency management to incentivize adherence. The study will refine the YORS approach through stakeholder input and pilot testing, followed by a randomized controlled trial to evaluate its efficacy. The goal is to develop effective strategies to address the opioid crisis in this vulnerable population.

Who should consider this trial

Good fit: Ideal candidates are young adults aged 18-28 diagnosed with opioid use disorder who are willing to engage in treatment with extended release naltrexone or buprenorphine.

Not a fit: Patients with psychiatric or medical instability or those living more than 75 miles from the treatment center may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance treatment adherence and outcomes for young adults struggling with opioid use disorder.

How similar studies have performed: Preliminary results from a small pilot randomized clinical trial of the YORS model have shown promising outcomes, indicating potential for success in larger studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-28
* OUD diagnosis
* Willing (intending) to receive treatment with XR-NTX or XR-BUP under the care of a MTC physician/nurse practitioner
* Willingness to designate family member (or other suitable treatment significant other) for treatment involvement (i.e., a treatment significant other; TSO)

Exclusion Criteria:

* Psychiatric or medical instability (e.g., suicidality, psychosis, Sickle Cell disease with frequent crises) that would preclude participation in the trial
* Living situation (location greater than 75 miles from the center, homelessness) that would preclude participation in the trial

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid-use DisorderMedication Adherence
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.