Condition

Influenza clinical trials and research

• 54Clinical trials
• 475NIH research projects
• 1New in 30 days
• 45Countries

Newest Influenza clinical trials

All recruiting trials (54)

• High-dose vs standard-dose flu vaccine in adults with blood cancers on B-cell-depleting therapy

  This study tests whether a high-dose flu shot evokes a stronger immune response than a standard-dose shot in adults with hematologic cancers who recently had B-cell-depleting therapy.

  Recruiting Phase 2 Asan Medical Center · Seoul · NCT07926217

• Abbott ID NOW at the point of care for flu-like illness in long-term care facilities

  This trial tests whether the Abbott ID NOW rapid test at the point of care in long-term care facilities can help identify influenza sooner for residents 65 and older with fever and respiratory symptoms.

  Recruiting China Medical University Hospital · Taichung · NCT07846423

• Egg-based H5N8 influenza vaccine at multiple doses with or without adjuvant in healthy adults

  This trial tests whether an egg-based H5N8 flu vaccine, given at low to high doses with or without an adjuvant, is safe and can provoke a stronger immune response in healthy adults 18 and older.

  Recruiting at 16 sites Phase 1/2 Sanofi · Tempe, Arizona and 15 other locations · NCT07779408

• Safety and PK of Ingavirin Forte vs Ingavirin in healthy adults under fasting and fed conditions

  This early-phase study tests whether Ingavirin Forte (90 mg + 20 mg) is safe and how it behaves in the body compared with Ingavirin (90 mg) in healthy adults aged 18–45, under different meal conditions.

  Recruiting Phase 1 Valenta Pharm JSC · Saint Petersburg · NCT07645534

• Light-based immune boost to help prevent viral upper respiratory infections

  A daily handheld light therapy device is tested to see if it can lower how often adults at a military medical facility get colds, flu, or other upper respiratory infections.

  Recruiting Mike O'Callaghan Military Hospital · Nellis Air Force Base, Nevada · NCT07610967

• Virological Monitoring of Seasonal Respiratory Infections in France

  This project tests how often common respiratory viruses show up in patients seen by primary care doctors in metropolitan France during the fall and winter.

  Recruiting Institut National de la Santé Et de la Recherche Médicale, France · Paris · NCT07599449

• Flu vaccine strategies for adults with blood cancers

  This study will test three different flu vaccines to see which gives the strongest antibody and T-cell responses in adults with blood cancers, including people after autologous stem cell transplant or CAR-T therapy.

  Recruiting Phase 3 Asan Medical Center · Seoul · NCT07485855

• Immune Defense Protein's effect on cold and flu symptoms in older adults

  This project will test whether the IDP® supplement shortens and eases cold and flu symptoms in people aged 60 and older.

  Recruiting Quantec Ltd · Los Angeles, California · NCT07431840

• Different doses of Ingavirin Forte capsules for adults with influenza or other acute respiratory infections.

  This trial will see if different doses of Ingavirin Forte capsules help adults (18–65) with PCR-confirmed influenza or other acute respiratory viral infections.

  Recruiting at 11 sites Phase 2 Valenta Pharm JSC · Ivanovo and 10 other locations · NCT07420985

• Influenza split vaccine for people aged 60 and older

  This trial will test whether a split influenza vaccine is safe and triggers an immune response in people aged 60 and older compared with a different vaccine formulation and a placebo.

  Recruiting Phase 1 Shanghai Institute Of Biological Products · Wuhan, Hubei · NCT07302256

• Comparative Immunogenicity of Respiratory Virus Vaccines (CIRV2) in Adults

  This study tests and compares the immune responses and tolerability of the latest COVID-19 vaccines from Novavax and Pfizer/BioNTech in adults at risk for severe COVID-19.

  Recruiting Phase 4 Henry M. Jackson Foundation for the Advancement of Military Medicine · Bethesda, Maryland · NCT07287137

• Suraxavir marboxil and oseltamivir to prevent flu spread in hospitals

  This study will see if giving suraxavir marboxil or oseltamivir to hospital roommates of people with confirmed flu prevents them from getting infected.

  Recruiting Phase 3 Capital Medical University · Beijing, Beijing Municipality and 1 other locations · NCT07236814

• Onradivir tablets for adolescents with uncomplicated influenza A

  This study tests whether Onradivir tablets help 12- to 17-year-olds with uncomplicated influenza A when given for 5 days, compared with a placebo.

  Recruiting Phase 3 Ruijin Hospital · Shanghai, Shanghai Municipality · NCT07229547

• BPL-1357 influenza vaccine by nasal spray or injection for H1N1 exposure

  Test whether two doses of the BPL-1357 flu vaccine, given by nasal spray or by injection, protect healthy adults 18–55 from H1N1 after controlled exposure.

  Recruiting Phase 2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland and 1 other locations · NCT07215858

• High-dose versus standard-dose flu vaccine for lung transplant recipients

  This study will test whether two yearly doses of the high‑dose flu vaccine produce stronger immune responses than two yearly standard‑dose flu vaccines in people who have received a lung transplant.

  Recruiting Phase 2 Vanderbilt University Medical Center · Nashville, Tennessee · NCT07192458

• First use of VNT-101 in people to test safety and how the body handles it

  This Phase 1 trial will test whether single and multiple oral doses of the experimental antiviral VNT-101 are safe and tolerable in healthy adults aged 18–59.

  Recruiting Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · Overland Park, Kansas · NCT07169318

• Protective shot against flu: MK-1406 (CD388) given as a one-time dose to teens and adults at higher risk

  This study tests whether a single dose of MK-1406 (CD388) can help prevent influenza in people who are more likely to get seriously ill, compared with a placebo.

  Recruiting at 93 sites Phase 3 Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) · Anniston, Alabama and 210 other locations · NCT07159763

• Understanding how brain changes relate to smell disorders over time

  This small, year-long study tests how brain activity and smell-related inflammation relate to different smell disorders in adults.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT07149428

• Blinded pH1N1 (H1N1) viral challenge in healthy adults

  This will try different doses of the pH1N1 (H1N1) influenza virus or a sham inoculation in healthy adults to find the dose that reliably produces mild infection for use in future flu tests.

  Recruiting at 2 sites Phase 1 National Institute of Allergy and Infectious Diseases (NIAID) · Baltimore, Maryland and 1 other locations · NCT07110532

• Immune responses in dengue and sepsis

  This project will collect blood from people hospitalized with dengue-like illness or sepsis and from healthy volunteers to see how their immune responses change over time.

  Recruiting at 4 sites Institut Pasteur du Cambodge · Kampong Speu and 3 other locations · NCT07040202

• Monitoring and detection of influenza, RSV, and COVID-19 in adults with and without HIV in Lusaka

  This project will test methods to detect influenza, RSV, and COVID-19 in adults with and without HIV who have recent respiratory symptoms in Lusaka.

  Recruiting at 2 sites Centre for Infectious Disease Research in Zambia · Lusaka, Lusaka Province and 1 other locations · NCT07030075

• Testing the safety and effects of Ingavirin Forte in healthy volunteers

  This study is testing different doses of Ingavirin Forte in healthy adults to see how safe it is and how well the body handles it.

  Recruiting Phase 1 Valenta Pharm JSC · Moscow · NCT06859333

• Do inactive H5N1 particles in pasteurized milk show up on nasal or throat tests?

  This study will test whether healthy adults who drink pasteurized milk containing killed H5N1 virus have the virus detected in nasal or throat swabs.

  Recruiting Emory University · Atlanta, Georgia · NCT06850298

• Examining immune responses to influenza and COVID-19 infections

  This study is testing how people's immune systems respond to influenza and COVID-19 infections by comparing vaccinated and unvaccinated individuals.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT06848309

• Wood smoke and nasal immune response to the flu

  This study will test if a short, two-hour wood smoke exposure changes nasal immune responses, symptom severity, and antibody production after a live nasal flu vaccine in healthy adults aged 18 to 49.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06841913

• Web-based program to improve pregnant mothers' understanding of and intent to get influenza and Tdap vaccines.

  This trial will test whether a short web-based education program helps pregnant women understand and feel more likely to get influenza and Tdap vaccines.

  Recruiting at 4 sites Universiti Putra Malaysia · Bandar Baru Bangi, Selangor and 3 other locations · NCT06815250

• Understanding immune responses to the flu virus

  This study is testing how the immune system responds to a specific flu virus in healthy volunteers to help create better vaccines and treatments for the flu.

  Recruiting at 2 sites Phase 1 Emory University · Atlanta, Georgia and 1 other locations · NCT06753474

• Effects of suctioning on pain and stress in intubated ICU patients

  This study is testing if suctioning the breathing tube in ICU patients causes more pain and stress compared to not suctioning.

  Recruiting Loma Linda University · Loma Linda, California · NCT06692400

• Comparing immune responses to influenza vaccination and infection in healthy adults

  This study tests how healthy adults respond to the flu vaccine and a flu virus to see which one helps their immune system better.

  Recruiting Imperial College London · London · NCT06620185

• Evaluating COVID-19 and influenza vaccine schedules for immunocompromised individuals

  This study is testing different ways to give COVID-19 and flu vaccines to people with weakened immune systems to see which method works best for their protection.

  Recruiting at 2 sites Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 2 other locations · NCT06599658

• Assessing GP681 for preventing influenza after exposure

  This study tests if a new flu medication called GP681 can help prevent influenza in people who have been exposed to someone with the virus.

  Recruiting Phase 3 Jiangxi Qingfeng Pharmaceutical Co. Ltd. · Hanzhou · NCT06574503

• Evaluating dexamethasone for severe influenza

  This study is testing whether the medication dexamethasone can help hospitalized patients with severe influenza recover better than those who receive a placebo.

  Recruiting at 2 sites Phase 3 Instituto de Investigación Sanitaria y Biomédica de Alicante · Alicante and 1 other locations · NCT06528444

• A program to empower community health workers to combat vaccine misinformation

  This study is testing a program that helps community health workers from Hispanic backgrounds use their personal stories to fight vaccine misinformation and boost vaccination rates in their communities.

  Recruiting University of Chicago · Chicago, Illinois and 3 other locations · NCT06417762

• Investigating the role of specific neutrophils in influenza outcomes

  This study is trying to see if certain types of white blood cells in people with severe influenza can help explain why some patients survive while others do not.

  Recruiting University Hospital, Bordeaux · Bordeaux and 1 other locations · NCT06254313

• Study on influenza and COVID-19 effects in pregnant women in India

  This study is testing how getting both COVID-19 and influenza affects pregnant women and their babies, while also looking at how vaccinations might help reduce risks during pregnancy.

  Recruiting at 2 sites Boston University · Boston, Massachusetts and 1 other locations · NCT06168019

• Understanding COVID-19 treatment effectiveness in Veterans

  This study looks at how well COVID-19 treatments work for Veterans with mild to moderate illness and compares those who receive treatment to those who don’t.

  Recruiting VA Office of Research and Development · Portland, Oregon · NCT06160128

• Evaluating the effectiveness of baloxavir marboxil for treating influenza in young children

  This study is testing if a new flu medication works well in young children aged 1 to under 12 who have been diagnosed with influenza.

  Recruiting at 20 sites Phase 3 Hoffmann-La Roche · Birmingham, Alabama and 50 other locations · NCT06094010

• Comparing two flu vaccines for older adults

  This study is testing which of two flu vaccines works better for adults aged 65 and older to prevent the flu and related health issues.

  Recruiting Kaiser Permanente · Oakland, California · NCT06029933

• Comparing high and standard dose influenza vaccines in pediatric organ transplant recipients

  This study is testing whether a higher dose of the flu vaccine works better and is safe for kids aged 3 to 17 who have recently received an organ transplant.

  Recruiting at 11 sites Phase 2 National Institute of Allergy and Infectious Diseases (NIAID) · Stanford, California and 10 other locations · NCT05947071

• Evaluating a standardized influenza vaccination program for hospitalized children

  This study is testing a new program to see if a standardized approach to giving flu shots can increase vaccination rates among children who are hospitalized in different hospitals across the U.S.

  Recruiting at 2 sites University of Colorado, Denver · Chicago, Illinois and 1 other locations · NCT05832307

• Comparing antiviral treatments for early symptomatic influenza

  This study is testing different antiviral medications to see which ones work best for people with early symptoms of the flu who are otherwise healthy.

  Recruiting at 4 sites Phase 2 University of Oxford · Minas Gerais and 3 other locations · NCT05648448

• Evaluating immune responses to the flu vaccine in healthy adults

  This study tests how well the flu vaccine works in healthy adults by looking at their immune responses over the course of a year.

  Recruiting Phase 4 Emory University · Atlanta, Georgia · NCT05616546

• Examining immune responses to the flu virus

  This study tests how the immune system responds to the H3N2 flu virus in healthy people to help improve future flu vaccines and treatments.

  Recruiting at 2 sites Phase 1 Emory University · Atlanta, Georgia and 1 other locations · NCT05332899

• Comparing immune responses to two influenza vaccines in older adults

  This study is testing whether a high-dose flu vaccine works better than a standard-dose flu vaccine for older adults living in nursing homes to help protect them from influenza.

  Recruiting Phase 2 Yale University · New Haven, Connecticut · NCT05291676

• Collecting samples from people with respiratory virus infections

  This study is collecting blood and nasal samples from people aged 3 and older who have respiratory virus infections to help researchers learn more about these viruses and improve vaccines and treatments.

  Recruiting at 2 sites National Institutes of Health Clinical Center (CC) · Bethesda, Maryland and 1 other locations · NCT05266222

• Stopping antibiotics for viral respiratory infections

  This study is testing if hospitalized adults with viral respiratory infections can safely stop taking antibiotics without affecting their recovery compared to those who keep taking them.

  Recruiting at 8 sites Phase 4 University Hospital, Akershus · Bergen and 11 other locations · NCT05045612

• Using digital devices to monitor respiratory virus infections

  This study is testing whether wearable devices like smartwatches can help track health changes in people with respiratory virus infections to better understand how severe the illness might be.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT04772170

• Combining baloxavir and oseltamivir to treat severe influenza in immunocompromised patients

  This study is testing if combining two antiviral medications, baloxavir and oseltamivir, can help people with severe influenza who have weakened immune systems due to cancer treatments feel better compared to just using oseltamivir alone.

  Recruiting Phase 2 M.D. Anderson Cancer Center · Houston, Texas · NCT04712539

• Surveillance network for pediatric infectious diseases

  This study is trying to see if training pediatricians to use new testing tools and shared records can help them diagnose and treat infectious diseases in children better.

  Recruiting Association Clinique Thérapeutique Infantile du val de Marne · Créteil · NCT04471493

• Using N-acetylcysteine with Oseltamivir for Severe Influenza in Hospitalized Adults

  This study is testing if adding N-acetylcysteine to the usual flu treatment can help hospitalized adults with severe influenza and pneumonia feel better faster.

  Recruiting Phase 3 Chinese University of Hong Kong · Hong Kong · NCT03900988

• Understanding immune responses to influenza vaccination in health care workers

  This study looks at how the flu vaccine affects the immune system of health care workers over ten years to see how well it protects them from the virus.

  Recruiting Finnish Institute for Health and Welfare · Helsinki · NCT03323112

• Evaluating treatments for severe community-acquired pneumonia in ICU patients

  This study tests different treatment options for ICU patients with severe pneumonia to see which ones work best, including special strategies for those with COVID-19.

  Recruiting at 234 sites Phase 3 UMC Utrecht · Jacksonville, Florida and 407 other locations · NCT02735707

• Influenza vaccination for adults over 75 years old

  This study tests how well the flu vaccine works for adults over 75, especially looking at how a common virus might affect their immune response.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT02200276

• Healthy volunteers needed for studies on Zika and influenza

  This study is looking for healthy volunteers to help researchers learn more about Zika and influenza by collecting samples and seeing how the body reacts to the flu virus.

  Recruiting National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT01386424

NIH-funded research (newest 40 of 475)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Creating vaccines for influenza and other infectious diseases

  This study is all about creating new vaccines to help protect people from the flu and other infections, so patients can look forward to better options for staying healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-9952278

• Creating vaccines for human trials against influenza and other infectious diseases

  This study is working on creating new vaccines to help protect people from flu and other infectious diseases, including those that could be used in harmful situations, so that everyone can have safer and more effective options to stay healthy.

  NIH research International AIDS Vaccine Initiative · New York, United States · NIH-9789450

• Understanding flu and COVID-19 vaccine responses in people and in the lab

  Researchers at Stanford explore how flu and COVID-19 vaccines work in people and in lab tests to improve protection for adults.

  NIH research Stanford University · Stanford, United States · NIH-11591264

• Surveillance and preparedness for flu and other respiratory pathogens in Kenya

  A US-based research grant aims to improve how Kenya detects and prepares for influenza and other respiratory diseases to protect people there and global health.

  NIH research Washington State University · Pullman, United States · NIH-11576443

• Enhanced Seasonal Influenza Vaccine Targeting Shared and Variable Viral Antigens

  A new DNA-based influenza vaccine approach aims to provide both precise protection against circulating strains and broader defense against unexpected strains.

  NIH research Orlance, INC. · Seattle, United States · NIH-11532352

• How the immune system responds to flu shots and flu infection

  This project looks at how adults' immune systems react after flu shots or when they catch the flu to find why some people get better protection than others.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11481644

• Influenza and SARS-CoV-2 in pregnancy in India

  A study following pregnant women in India to track how flu and COVID viruses affect mothers and newborns.

  NIH research Boston University Medical Campus · Boston, United States · NIH-11478436

• Predicting which flu strains vaccines should target

  This work uses computer and biophysical models to forecast which flu virus strains are likely to spread so vaccines can better protect people.

  NIH research Sloan-Kettering Inst Can Research · New York, United States · NIH-11468406

• How flu antibodies attach to the virus

  This project looks at how antibodies from people of different ages stick to flu virus proteins to help make better vaccines.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11468148

• Flu vaccine designs that target the HA and NA proteins

  Developing vaccine pieces that teach the immune system to recognize shared parts of flu viruses so more people can get broader protection.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11468147

• How flu infection and vaccination shape B cell immune memory

  This project compares how first flu infections versus first flu vaccines change antibody responses in children and adults to help make better vaccines.

  NIH research Boston Children's Hospital · Boston, United States · NIH-11468145

• Understanding how influenza becomes contagious: host, droplets, and environment

  A research team is studying what makes influenza-infected people more contagious by looking at the person, the droplets they breathe out, and the environment, using advanced AI and ferret models.

  NIH research St. Jude Children's Research Hospital · Memphis, United States · NIH-11451546

• Understanding how T cells influence influenza transmission in a pig model

  This project looks at how immune T cells may affect how influenza spreads, using pigs to model human-like transmission and immune responses.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11451506

• Antibody and environmental factors shaping flu spread

  A study to understand how antibodies and air conditions influence how easily flu spreads from one person to another, using a pig model to mimic human transmission.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11451505

• How our immune system affects how flu spreads through the air

  This grant looks at how our antibodies and environmental factors like temperature and humidity influence how airborne flu spreads, with studies in animals and people.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11451501

• How influenza spreads through the air and environment: a project to understand real-world transmission

  This grant studies how environmental conditions and the contents of respiratory fluids influence influenza virus spread in real-world spaces.

  NIH research Duke University · Durham, United States · NIH-11451344

• Nasal microbiome and how it shapes defense against flu and its spread

  A Duke-led project looks at how the nasal microbes influence how our bodies defend against influenza and how easily the virus spreads.

  NIH research Duke University · Durham, United States · NIH-11451343

• Mucosal antibodies to stop flu spread in people

  A Duke-led project aims to understand how antibodies in the nose and throat help prevent influenza from spreading between people.

  NIH research Duke University · Durham, United States · NIH-11451342

• COMMIT Center: new clues on how flu spreads between people

  A Duke-led center is studying what biological and environmental factors influence how influenza moves from person to person.

  NIH research Duke University · Durham, United States · NIH-11451337

• How households and neighborhoods influence flu spread

  A broad study at the University of Michigan will look at how people’s daily behavior, home environments, and neighborhood air conditions affect how flu spreads inside households.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11449663

• Connecting respiratory virus spread, co-infections, and symptoms to real-world flu transmission

  A large, community-based study in Michigan will track how flu spreads in households, including how coinfections and symptoms relate to real-world transmission.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11449661

• Resource toolkit to study how influenza spreads between people

  A program to build and share new tools, models, and methods so researchers better understand how flu spreads from person to person.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11449660

• Understanding How Flu Spreads in People Using Real-World Data

  This grant studies how influenza spreads from person to person by analyzing real-world data from people and communities to improve prevention and control.

  NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11449658

• Pleomorphic influenza virus shape and how long it survives outside the body

  This grant investigates how different shapes of influenza viruses behave in real-world air and surfaces, and what that means for how easily the virus could spread.

  NIH research Duke University · Durham, United States · NIH-11440778

• Understanding how a non-traditional ISG15 helps or hinders flu virus control

  A small NIH-funded project will explore how a specific human immune gene, ISG15, and its different forms affect influenza virus infection in cells.

  NIH research Loyola University Chicago · Maywood, United States · NIH-11440558

• Influenza, Hydroxychloroquine, and the Windows of Self-Peptide Presentation in Lupus

  A doctor-researcher is studying how flu infection and the lupus medication hydroxychloroquine change the way the immune system shows self-parts to trigger or prevent lupus flares in kids.

  NIH research Children's Hosp of Philadelphia · Philadelphia, United States · NIH-11438703

• Immunometabolic mediators of liver injury in influenza infection

  This grant explores how liver injury happens during severe flu with ARDS and how immune signals outside the lungs contribute to organ damage.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-11437407

• Reassortment of Bird Flu Viruses and How They Adapt and Reach New Hosts

  This grant studies how highly contagious bird flu viruses mix and adapt so they can infect different animals and people.

  NIH research Emory University · Atlanta, United States · NIH-11434358

• How childhood flu exposures shape immunity to future pandemic viruses

  This NIH project studies how the flu we encounter in childhood shapes our antibody responses to different flu strains later in life.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11432486

• Universal flu vaccine using self-assembling protein nanoparticles to present HA, NA, and M2e

  Researchers are testing a new nanoparticle vaccine designed to trigger broad protection against many flu strains for people of all ages.

  NIH research Scripps Research Institute, the · La Jolla, United States · NIH-11429747

• Broad NA antibody vaccines to protect against diverse influenza strains

  Researchers are designing vaccines focused on neuraminidase antibodies to help protect people from a wide range of flu strains.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11429474

• Role of the body’s blood-pressure system in how our body fights flu in the lungs

  This grant studies how the body’s RAAS system affects lung inflammation during influenza infection to understand why some people develop severe illness.

  NIH research University of Maine Orono · Orono, United States · NIH-11423614

• Text reminders to help families with children's flu shots

  Helpful text messages will give families clear information about kids' flu risks, vaccine safety, and how to get vaccinated.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11422381

• Immunity in the Nose to Flu: Correlates of Vaccine Efficacy

  Researchers are studying how immune protection in the nose helps prevent flu infection and how to improve vaccines, using easy nasal sampling to learn what works best.

  NIH research Imperial College of Science, Technology and Medicine · London, United Kingdom · NIH-11420443

• Understanding how bird flu viruses switch to highly dangerous forms

  Researchers are studying how bird flu viruses change to become highly dangerous in poultry to help prevent outbreaks that harm animals and people.

  NIH research Erasmus Medical Center · Rotterdam, NETHERLANDS · NIH-11418524

• Understanding how the mother’s immune signals affect a baby’s brain during flu during pregnancy

  Aims to find immune signals crossing the placenta during flu infection in pregnancy that could affect fetal brain development in babies.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-11413853

• Motivational interviewing to increase COVID-19 and flu vaccination

  This project teaches primary care providers conversational skills to help more adults, especially those in vulnerable communities, feel comfortable getting COVID-19 and flu shots.

  NIH research Univ of Massachusetts Med Sch Worcester · Worcester, United States · NIH-11412464

• Shelf-stable universal flu vaccine to protect against many strains

  A new shelf-stable, dry-powder flu vaccine is being developed to provide broad protection and easier distribution, especially where cold storage is limited.

  NIH research Via Therapeutics, LLC · Austin, United States · NIH-11406923

• A potential universal flu vaccine that targets a stable flu protein (NP)

  This project develops a new vaccine meant to protect people from many different flu strains by targeting a stable flu protein called nucleoprotein (NP).

  NIH research Osivax Sas · Paris, France · NIH-11401256

• Understanding how lung fibroblasts drive inflammation after flu infection

  Researchers aim to understand why some people have long-lasting lung problems after influenza and look for ways to help recovery.

  NIH research University of California Santa Cruz · Santa Cruz, United States · NIH-11399157

Related topics

Quick answers

How many Influenza clinical trials are recruiting right now?

54, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 45 countries. The most sites are in United States (31 trials), China (4 trials), France (4 trials), Spain (3 trials), United Kingdom (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 9, Phase 2: 9, Phase 1: 7, Phase 4: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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