NIH-funded research R21 grant

Pleomorphic influenza virus shape and how long it survives outside the body

Official title: Pleomorphic morphology as a determinant of environmental stability of influenza virus

Funded at Duke University · NIH-11440778 · Data updated 2026-11-12

This grant investigates how different shapes of influenza viruses behave in real-world air and surfaces, and what that means for how easily the virus could spread.

More Influenza research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startSeptember 4, 2026
Project endAugust 31, 2028
Funding year2026
Award (this year)$192,587
NIH project number1R21AI203156-01
Project IDNIH-11440778 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable; this is a basic science study. No direct patient participation is required.

Less likely to help

No direct patient participation or benefit in this specific project.

What this research studies

Researchers will study how the pleomorphic (shape-changing) influenza virus persists in respiratory droplets under varying environmental conditions, such as humidity and temperature. They will use controlled environmental settings to see how shape and growth conditions influence infectivity over time. The work aims to connect virus form with stability outside a person, potentially informing public health strategies to limit transmission.

Why it matters

Potential benefit: If successful, findings could help improve guidance on how long influenza remains contagious in the environment and inform prevention measures.

How similar studies have gone: Previous work shows environmental factors affect influenza stability, but how pleomorphic shape changes this is not yet known.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Rockey, Nicole C — Duke University
  • Study coordinator: Rockey, Nicole C

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.