International collaboration to collect information on adults hospitalized with acute infections

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, longitudinal observational protocol enrolls adults admitted to hospital (or in the emergency department with expected admission) for suspected or confirmed acute infectious diseases within 30 days of symptom onset. Participating sites collect clinical data, laboratory results, and biospecimens over time without providing experimental treatments. The design covers respiratory and non-respiratory infections, established infectious diseases, and emerging pathogens. Generated data and samples are intended to characterize disease course and biology and to inform the selection and design of future interventional trials.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years old
* Admitted to hospital (or in an emergency department with anticipated hospital admission) for the management of a suspected or confirmed acute infectious disease.
* Onset of symptoms of an infectious disease within the past 30 days.
* Informed consent for study participation by the participant or a surrogate decision maker if the participant lacks capacity for consent.

Exclusion Criteria:

* Current imprisonment (this does not include quarantine for an infectious disease).
* Patient undergoing comfort care measures only such that treatment focuses on end- of-life symptom management over prolongation of life.
* Expected inability or unwillingness to participate in study procedures.
* In the opinion of the investigator, participation in the study is not in the best interest of the patient.

Where it's running

• Banner University Medical Center Tucson
  Tucson, Arizona, United States Recruiting
• Stanford University Hospital & Clinics (Site 203-003)
  Palo Alto, California, United States Recruiting
• UCSF Medical Center (Site 203-001)
  San Francisco, California, United States Recruiting
• Orlando VA Medical Center (074-032)
  Orlando, Florida, United States Recruiting
• University of Illinois at Chicago (Site 008-012)
  Chicago, Illinois, United States Recruiting
• Lutheran Medical Group
  Fort Wayne, Indiana, United States Recruiting

+6 more sites. See ClinicalTrials.gov for the full list.

Study contacts

• Principal investigator: Cavan Reilly, PhD — University of Minnesota
• Study coordinator: Rebecca Schoenecker
• Email: webe0376@umn.edu
• Phone: 612-624-9644

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.