Exercise and Heart Health in Women at Risk for Pregnancy Complications

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial aims to evaluate the cardiovascular profile of pre-conceptional women who are at risk for developing gestational hypertensive disorders (GHD) before and after a structured exercise program. Participants will be randomly assigned to one of three groups: a non-supervised exercise group, a supervised non-infrared exercise group, or a supervised infrared exercise group. The study will assess changes in cardiovascular health over a 12-week period, with evaluations at baseline, 6 weeks, 12 weeks, and 18 weeks. The trial also seeks to understand the impact of exercise type and supervision on cardiovascular improvements.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women at risk for the development of GHD in subsequent pregnancy based on the presence of at least one of the following risk factors:

  * high body mass index (BMI\>30 kg/m²)
  * a family history of PE (mother, sister)
  * in the need of assisted reproduction techniques in a previous or subsequent pregnancy
  * maternal comorbidities: prior PE, diabetes mellitus, chronic hypertension, chronic kidney disease or antiphospholipid syndrome
* Non-pregnant (as confirmed by a negative pregnancy urine dipstick test)
* Age ≥ 18 years
* Being able to understand the Dutch language

Exclusion Criteria:

Participants eligible for this study must not meet any of the following criteria:

* Pregnant at inclusion
* Not being able to exercise according to physician's decision
* Suffering from underlying diseases that can affect the CV profile such as oncological diseases coronary heart disease, aortic disease, peripheral arterial disease
* Participating in another clinical study that may alter the results of this study

Where it's running

• Hasselt University
  Diepenbeek, Limburg, Belgium Recruiting

Study contacts

• Principal investigator: Dorien Lanssens — UHasselt
• Study coordinator: Pauline Dreesen
• Email: pauline.dreesen@uhasselt.be
• Phone: 089212030

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.