Clinical trial Recruiting at 1 site Observational Ages 18 and up Women only

Postoperative Pain Trajectories After Endometriosis Surgery

Official title: Pain Trajectories After Surgery for Endometriosis: A 6-Month Prospective Monocentric Study

Run by Centre Hospitalier Universitaire, Amiens · NCT07882498 · Data updated 2026-11-12

This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment150 (estimated)
SponsorCentre Hospitalier Universitaire, Amiens
Academic / other
Locations1 site (Amiens)
StatusRecruiting
StartedJuly 7, 2026
Main results expectedJuly 2028
Study endsJanuary 2029
Registry record updatedOctober 20, 2026
Trial IDNCT07882498 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with imaging-confirmed endometriosis scheduled for surgical treatment and affiliated with the French Social Security system.

Probably not a fit

Patients who do not experience chronic postoperative pain or who do not complete follow-up may not derive predictive benefit from the testing.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-centre observational study will follow adults with confirmed endometriosis undergoing surgery to map their pain trajectories at multiple time points up to 6 months. It will combine perioperative quantitative sensory testing with patient-reported outcomes to explore predictors of chronic postoperative pain. The goal is to identify distinct pain patterns and see if early tests can forecast long-term pain after surgery. Analyses will focus on mechanical and pressure pain sensitivity, temporal summation, and standard pain questionnaires. Follow-ups are planned for day 2, day 14, and later time points to characterize trajectory.

Why it matters

Potential benefit: If successful, the study could help clinicians anticipate which patients are at higher risk for persistent pain and tailor perioperative care accordingly.

How similar studies have gone: Prior work shows that pain trajectories and quantitative sensory testing can relate to postoperative pain in other conditions; this study applies similar concepts to endometriosis with observational design.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Imaging-confirmed endometriosis
* Scheduled surgical treatment for endometriosis
* Affiliation to the French Social Security system
* Written informed consent obtained

Exclusion Criteria:

* Patients under legal protection (guardians or curators)
* History of psychiatric disorders
* Neurodegenerative diseases
* Inability to self-assess pain using a numerical rating scale
* Non-French-speaking patients
* Pregnancy or breastfeeding
* Refusal to participate

Where it's running

  • CHU Amiens-Picardie
    Amiens, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.