Condition

Catheter Ablation clinical trials and research

• 13Clinical trials
• 6NIH research projects
• 7Countries

Newest Catheter Ablation clinical trials

All recruiting trials (13)

• Non-invasive mapping to help treat ventricular tachycardia due to heart disease

  This study tests a non-invasive mapping tool to guide VT ablation in adults with structural heart disease and prior heart attack.

  Recruiting at 2 sites University of Warwick · Brighton and 2 other locations · NCT07759427

• Catheter ablation plus LAAC vs anticoagulation in frail elderly A-fib patients

  This study tests whether adding left atrial appendage closure to ablation is as good as using long-term blood thinners in frail people aged 75 and up with atrial fibrillation.

  Recruiting Guangdong Provincial People's Hospital · Guangzhou, Guangdong · NCT07441382

• Substrate remodelling and targeted ablation for persistent atrial fibrillation

  This project will try using detailed 3D electrical mapping of the left atrium to guide targeted ablation (pulmonary vein reisolation, ganglionic plexi, and substrate ablation) for people with persistent atrial fibrillation undergoing their first catheter ablation.

  Recruiting Barts & The London NHS Trust · London · NCT07047235

• Music during catheter ablation for atrial fibrillation under light sedation

  This test will see if playing music during catheter ablation helps adults having their first atrial fibrillation procedure feel less anxious and in less pain while using light sedation.

  Recruiting Shaoxing People's Hospital · Shaoxing, Zhejiang · NCT06953752

• Catheter ablation for people with persistent atrial fibrillation and severe atrial functional mitral regurgitation

  This will test whether adding catheter ablation to usual medicines helps adults with persistent atrial fibrillation and moderate-to-severe or severe atrial functional mitral regurgitation reduce valve leakage and improve symptoms and outcomes.

  Recruiting at 12 sites Beijing Anzhen Hospital · Hefei, Anhui and 16 other locations · NCT06883864

• Evaluating endomyocardial biopsy and tailored treatments for pediatric inflammatory heart disease

  This study is testing how a heart tissue sample and personalized treatments can help kids with inflammatory heart disease, especially those with myocarditis and heart rhythm issues.

  Recruiting Scientific Institute San Raffaele · Milan, Milano · NCT06591260

• Preventive catheter ablation for heart failure patients with ventricular arrhythmias

  This study is testing if a heart procedure called catheter ablation can help heart failure patients with irregular heartbeats live longer and feel better compared to standard treatment before they get a heart transplant.

  Recruiting Heart and Diabetes Center North-Rhine Westfalia · Bad Oeynhausen · NCT06556485

• Comparing cardioversion and ablation for persistent atrial fibrillation

  This study is testing whether a heart procedure called catheter ablation works better than a shock treatment to keep people with persistent atrial fibrillation from having their heart rhythm go out of sync again.

  Recruiting Barts & The London NHS Trust · London · NCT06096246

• Evaluating high power short duration RF for atrial fibrillation ablation

  This study is testing a new way to use radiofrequency energy for heart ablation to see if it helps people with atrial fibrillation feel better and stay healthy over the next year.

  Recruiting at 7 sites Clinica Mediterranea · Paris and 8 other locations · NCT05777551

• Personalized wide-area radiofrequency ablation plus pulmonary vein isolation versus pulsed-field pulmonary vein isolation for paroxysmal atrial fibrillation

  This trial will test whether a patient-tailored radiofrequency ablation that targets extra atrial sources plus pulmonary vein isolation prevents recurrent atrial fibrillation better than pulsed-field pulmonary vein isolation in adults with paroxysmal AF.

  Recruiting Ottawa Heart Institute Research Corporation · Ottawa, Ontario and 1 other locations · NCT04823299

• Comparing two methods for catheter ablation of atrial flutter

  This study is testing whether a new way of doing catheter ablation for atrial flutter can be safer and more effective than the standard method.

  Recruiting Klinikum-Fuerth · Fürth, Bavaria · NCT04678258

• Evaluating endomyocardial biopsy and tailored treatments for inflammatory heart disease

  This study is trying to see if a heart tissue test and personalized treatments can help people with inflammatory heart disease, especially those with myocarditis and heart rhythm issues.

  Recruiting Scientific Institute San Raffaele · Milan, Milano · NCT04521790

• Nationwide registry for catheter ablation treatment of cardiac arrhythmias in Japan

  This study is collecting information on how well catheter ablation works for treating heart rhythm problems in Japan to see how safe and effective the procedure is.

  Recruiting National Cerebral and Cardiovascular Center, Japan · Suita, Osaka · NCT03729232

NIH-funded research (6)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Catheter ablation plus standard heart failure care in HFpEF with atrial fibrillation

  A large multi-center study will test whether adding catheter ablation for atrial fibrillation to guideline-based heart failure treatment improves outcomes for people with HFpEF and AF.

  NIH research Ihc Health Services, INC. · Salt Lake City, UNITED STATES · NIH-11281754

• Catheter Ablation vs Antiarrhythmic and Heart Failure Drug Therapy for AF with HFpEF

  This project tests whether ablation or drug therapy improves outcomes for people with atrial fibrillation and heart failure with preserved ejection fraction.

  NIH research Duke University · Durham, United States · NIH-11281051

• Insertable heart monitor to catch early atrial fibrillation after catheter ablation

  This trial tests whether a small implanted heart monitor that finds early, often-silent atrial fibrillation and prompts early treatment can help people with drug-resistant atrial fibrillation after catheter ablation.

  NIH research University of Rochester · Rochester, United States · NIH-11176391

• Using a heart monitor to improve treatment outcomes for atrial fibrillation after catheter ablation

  This study is looking at how a small heart monitor can help catch early signs of atrial fibrillation returning after treatment, so that people can get the right help sooner, and it’s for patients who have had catheter ablation for this condition.

  NIH research University of Rochester · Rochester, United States · NIH-10908601

• Using advanced imaging techniques to improve heart procedure outcomes for atrial fibrillation

  This study is looking to make catheter ablation for atrial fibrillation more effective by using advanced imaging techniques to better understand heart anatomy, which could help doctors personalize treatment plans and improve results for patients like you.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-10869976

• Evaluating a new treatment approach for atrial fibrillation using renal artery denervation.

  This study is looking at whether combining a procedure called renal artery denervation with catheter ablation can help people with atrial fibrillation have better heart rhythm control and fewer episodes of AF.

  NIH research University of Rochester · Rochester, United States · NIH-10685356

Related topics

Quick answers

How many Catheter Ablation clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United Kingdom (4 trials), China (3 trials), Italy (3 trials), Germany (2 trials), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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