Using a heart monitor to improve treatment outcomes for atrial fibrillation after catheter ablation
Official title: Insertable Cardiac Monitor-Guided Early Intervention to Reduce Atrial Fibrillation Burden Following Catheter Ablation (ICM-REDUCE-AF Trial)
Funded at University of Rochester · NIH-10908601 · Data updated 2026-11-12
This study is looking at how a small heart monitor can help catch early signs of atrial fibrillation returning after treatment, so that people can get the right help sooner, and it’s for patients who have had catheter ablation for this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 1, 2021 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $528,072 |
| NIH project number | 5R33HL153001-04 |
| Project ID | NIH-10908601 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals with drug-refractory paroxysmal or persistent atrial fibrillation who are scheduled for catheter ablation.
✕Less likely to help
Patients who do not have atrial fibrillation or those who are not candidates for catheter ablation may not benefit from this research.
What this research studies
This research investigates how an insertable cardiac monitor can help detect early signs of atrial fibrillation recurrence after catheter ablation. Patients will be monitored continuously to identify subclinical atrial fibrillation, allowing for timely interventions. The study involves randomizing participants into two groups: one receiving early intervention based on monitor data and another following standard care. This approach aims to reduce the burden of atrial fibrillation and improve overall heart health.
Why it matters
Potential benefit: If successful, this research could lead to better management of atrial fibrillation, reducing the frequency of episodes and improving patients' quality of life.
How similar studies have gone: Previous research has shown that continuous monitoring can improve outcomes in patients with atrial fibrillation, suggesting this approach may be effective.
Where this research is happening
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University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Goldenberg, Ilan — University of Rochester
- Study coordinator: Goldenberg, Ilan
Related research
Other NIH-funded projects on the same topics.
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Insertable heart monitor to catch early atrial fibrillation after catheter ablation
This trial tests whether a small implanted heart monitor that finds early, often-silent atrial fibrillation and prompts early treatment can help people with drug-resistant atrial fibrillation after catheter ablation.
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Using advanced imaging techniques to improve heart procedure outcomes for atrial fibrillation
This study is looking to make catheter ablation for atrial fibrillation more effective by using advanced imaging techniques to better understand heart anatomy, which could help doctors personalize treatment plans and improve results for patients like you.
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This study is looking at whether combining a procedure called renal artery denervation with catheter ablation can help people with atrial fibrillation have better heart rhythm control and fewer episodes of AF.
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A researcher at Baylor College of Medicine is studying how signals between heart muscle cells and supportive heart cells influence atrial fibrillation, with the goal of finding new ways to prevent or treat this common heart rhythm problem.
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This project looks at how to safely use blood-thinning medicines in people who survived a brain bleed and also have atrial fibrillation and small vessel disease.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.