Comparing two methods for catheter ablation of atrial flutter

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial compares two approaches for catheter ablation of the cavo-tricuspid isthmus (CTI) in patients with typical atrial flutter. One method is the conventional linear ablation, while the other is a maximum voltage-guided (MVG) technique that targets high voltage areas to potentially reduce ablation duration and radiation exposure. The study aims to provide robust evidence on the efficacy and safety of the MVG approach compared to the standard method. Participants will undergo detailed mapping and signal analysis to identify the best treatment strategy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Typical (CTI dependent) atrial flutter documented in a standard 12 lead surface ECG
* Given class I indication for curative CTI ablation according to the current guidelines
* Over 18 years old
* Given informed consent

Exclusion Criteria:

* Any contraindication for CTI ablation
* Previous CTI ablation
* BCB as procedural endpoint not assessable
* CTI ablation conducted in association with further ablation procedures
* Patients with CIED (e.g. pacemaker, ICD)
* Tricuspid valve replacement
* Right atrial thrombus
* Pregnant or breastfeeding women
* Abuse of drugs or alcohol
* Age \< 18 years
* Incompliance to the treatment, e.g. necessary anticoagulation
* Expected survival less than one year
* Inability to understand the nature and rationale of the study
* Inability to take part in the follow up

Where it's running

• Klinikum Fuerth
  Fürth, Bavaria, Germany Recruiting

Study contacts

• Principal investigator: Dirk Bastian, MD — Klinikum-Fuerth
• Study coordinator: Dirk Bastian, MD
• Email: dirk.bastian@klinikum-fuerth.de
• Phone: 7580 1101

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.