Using advanced imaging techniques to improve heart procedure outcomes for atrial fibrillation
Official title: RADIOMIC APPROACHES TO IMPROVE TARGETING FOR ATRIAL FIBRILLATION CATHETER ABLATION
Funded at Cleveland Clinic Lerner Com-Cwru · NIH-10869976 · Data updated 2026-11-12
This study is looking to make catheter ablation for atrial fibrillation more effective by using advanced imaging techniques to better understand heart anatomy, which could help doctors personalize treatment plans and improve results for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project start | July 15, 2021 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $716,119 |
| NIH project number | 5R01HL158071-04 |
| Project ID | NIH-10869976 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with atrial fibrillation who are considering catheter ablation as a treatment option.
✕Less likely to help
Patients who do not have atrial fibrillation or those who are not candidates for catheter ablation may not benefit from this research.
What this research studies
This research focuses on enhancing the effectiveness of catheter ablation for atrial fibrillation (AF) by utilizing advanced imaging techniques known as radiomics. By analyzing cardiac CT scans, the team aims to identify specific anatomical features that can predict the success of the ablation procedure. The study will employ machine learning methods to analyze data from over 2000 patients, helping to personalize treatment plans and improve patient outcomes. This approach seeks to address the challenges of targeting the right areas in the heart during the ablation process.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatments for patients with atrial fibrillation, potentially reducing the risk of complications and improving long-term success rates.
How similar studies have gone: Previous research has shown promising results using similar imaging and machine learning approaches to improve outcomes in atrial fibrillation treatments.
Where this research is happening
-
Cleveland Clinic Lerner Com-Cwru
Cleveland, United States Active
Researchers
- Principal investigator: Chung, Mina Kay — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Chung, Mina Kay
Related research
Other NIH-funded projects on the same topics.
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Insertable heart monitor to catch early atrial fibrillation after catheter ablation
This trial tests whether a small implanted heart monitor that finds early, often-silent atrial fibrillation and prompts early treatment can help people with drug-resistant atrial fibrillation after catheter ablation.
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Using a heart monitor to improve treatment outcomes for atrial fibrillation after catheter ablation
This study is looking at how a small heart monitor can help catch early signs of atrial fibrillation returning after treatment, so that people can get the right help sooner, and it’s for patients who have had catheter ablation for this condition.
-
Evaluating a new treatment approach for atrial fibrillation using renal artery denervation.
This study is looking at whether combining a procedure called renal artery denervation with catheter ablation can help people with atrial fibrillation have better heart rhythm control and fewer episodes of AF.
-
Cardiomyocyte-fibroblast signaling in atrial fibrillation
A researcher at Baylor College of Medicine is studying how signals between heart muscle cells and supportive heart cells influence atrial fibrillation, with the goal of finding new ways to prevent or treat this common heart rhythm problem.
-
Anticoagulation in ICH Survivors with Atrial Fibrillation and Small Vessel Disease
This project looks at how to safely use blood-thinning medicines in people who survived a brain bleed and also have atrial fibrillation and small vessel disease.
-
Lowering heart inflammation to reduce atrial fibrillation risk in people with diabetes
Seeing whether blocking a pro-inflammatory enzyme or boosting the heart's natural inflammation-resolving signals can lower atrial fibrillation risk in people with diabetes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.