Condition

Cardiac Arrhythmia clinical trials and research

• 15Clinical trials
• 14NIH research projects
• 9Countries

Newest Cardiac Arrhythmia clinical trials

All recruiting trials (15)

• Chest-strap ECG wearable vs. traditional patch monitor in active adults

  This study tests whether the Frontier X Plus chest-strap ECG device can capture heart rhythms as well as the MoMe ARC patch in active adults who already need an ambulatory monitor.

  Recruiting at 3 sites Mayo Clinic · Scottsdale, Arizona and 2 other locations · NCT07772817

• BDNF Levels and Atrial Cardiomyopathy in People Having AF Ablation

  This study tests whether circulating BDNF levels are linked to atrial cardiomyopathy in adults having their first ablation for persistent atrial fibrillation.

  Recruiting Centre Hospitalier Universitaire Dijon · Dijon · NCT07648329

• nano-second pulsed field (nsPFA) catheter ablation for paroxysmal atrial fibrillation using the CellFX system

  The study will try the CellFX nano-second pulsed field catheter to treat adults with recurrent, drug-resistant paroxysmal atrial fibrillation.

  Recruiting Pulse Biosciences, Inc. · Prague, Roentgenova · NCT07018596

• Monitoring heart activity with a smart textile chest band

  This study tests a smart chest band that tracks heart activity for two weeks to see if it can help spot heart rhythm problems better.

  Recruiting Myant Medical Corp. · Newmarket, Ontario · NCT06870175

• Using a new catheter system to treat atrial fibrillation

  This study is testing a new catheter system to see if it safely helps people with paroxysmal atrial fibrillation feel better after treatment.

  Recruiting at 2 sites Pulse Biosciences, Inc. · Hasselt and 2 other locations · NCT06696170

• Ablation of focal activation in atrial fibrillation

  This study is testing a new method to find specific electrical signals that may be causing ongoing atrial fibrillation in patients, to see if targeting these signals can improve their treatment.

  Recruiting Imperial College London · London · NCT06402617

• HeartWatch vs Holter: A Longer-Term Arm Monitors Heart Rhythm

  This study tests whether the HeartWatch arm monitor can match or improve on Holter monitoring for detecting rhythm problems in adults with suspected AF and other arrhythmias.

  Recruiting HelpWear Inc. · Calgary, Alberta · NCT06164808

• Comparing cardioversion and ablation for persistent atrial fibrillation

  This study is testing whether a heart procedure called catheter ablation works better than a shock treatment to keep people with persistent atrial fibrillation from having their heart rhythm go out of sync again.

  Recruiting Barts & The London NHS Trust · London · NCT06096246

• Using Colchicine to Prevent Atrial Fibrillation Recurrence After Heart Rhythm Restoration

  This study is testing if a low-dose Colchicine treatment can help prevent Atrial Fibrillation from coming back in people who have just had their heart rhythm restored.

  Recruiting at 8 sites Phase 3 University Hospital, Basel, Switzerland · Bruderholz, Basel-Landschaft and 7 other locations · NCT05890664

• Evaluating new technologies for successful atrial fibrillation ablation

  This study is testing how well a common heart procedure called catheter ablation works for people with atrial fibrillation over a year to see if it helps keep their heart rhythm steady.

  Recruiting Azienda Ospedaliero, Universitaria Pisana · Pisa · NCT05617456

• Collecting data on the safety and performance of BIOTRONIK EP products for cardiac arrhythmia.

  This study is testing how safe and effective BIOTRONIK's heart devices are for people getting treatment for heart rhythm problems.

  Recruiting Biotronik SE & Co. KG · Bernau bei Berlin, Brandenburg · NCT05560958

• Ablation of nerve endings in the right atrium for treating atrial fibrillation

  This study is testing a new procedure that targets nerve endings in the right side of the heart to help people with persistent atrial fibrillation who haven't found relief from standard treatments.

  Recruiting Imperial College London · London · NCT05539040

• Registry for patients with repaired Tetralogy of Fallot

  This study is collecting information from patients who have had surgery for Tetralogy of Fallot to see how their hearts are doing over time using special imaging tests.

  Recruiting Azienda Ospedaliero, Universitaria Ospedali Riuniti · Ancona, The Marches · NCT05288894

• Using targeted radiation to treat heart rhythm problems

  This study is testing whether a special type of targeted radiation can help people with tough heart rhythm problems that haven’t improved with regular treatments.

  Recruiting University Health Network, Toronto · Toronto, Ontario · NCT04843683

• Registry and biobank for arrhythmogenic ventricular cardiomyopathy

  This study is trying to gather information and samples from people with arrhythmogenic ventricular cardiomyopathy and their families to better understand the genetic causes of the condition and improve early diagnosis for those at risk.

  Recruiting at 2 sites Mayo Clinic · Rochester, Minnesota and 1 other locations · NCT03049254

NIH-funded research (14)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Precision imaging of heart rhythms to map arrhythmias without surgery

  A new 3D ultrasound method could noninvasively map how abnormal heart rhythms start and travel, helping doctors plan safer treatments for people with arrhythmias.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11385556

• New roles for a heart protein in preventing dangerous rhythms

  A heart study will explore how a specific protein regulator (PP2A) affects ion channels that control heartbeat, with the goal of reducing dangerous arrhythmias.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11375997

• Understanding how small potassium channels affect heart rhythm and disease

  Aims to understand how tiny calcium-activated potassium channels influence heart rhythm and potentially lead to new treatments for atrial fibrillation and heart failure.

  NIH research University of Arizona · Tucson, United States · NIH-11294983

• 3D ultrasound mapping to locate sources of abnormal heart rhythms

  This project uses a fast, radiation-free 3D ultrasound method to find where irregular heartbeats start in adults with arrhythmias.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11193775

• Understanding a New Way to Control Heart Rhythm Problems

  This work explores how a specific protein in the heart helps regulate electrical signals, aiming to find new ways to prevent dangerous heart rhythm issues.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11128719

• Exploring the mechanisms behind heart rhythm disorders

  This conference is all about helping doctors and researchers understand what causes irregular heartbeats, so they can find better ways to diagnose and treat these issues for people at risk of serious health problems like strokes or sudden heart failure.

  NIH research Gordon Research Conferences · East Greenwich, UNITED STATES · NIH-11065758

• AI and 4D ultrasound to pinpoint where abnormal heart rhythms begin

  Uses AI together with time-resolved 3D (4D) ultrasound to find where abnormal heart rhythms start in people with arrhythmias.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11062814

• Improving treatments for heart rhythm disorders

  This study is looking into how irregular heartbeats happen and aims to find better treatments for people with these heart issues, so they can feel safer and healthier.

  NIH research Vanderbilt University Medical Center · Nashville, United States · NIH-11031410

• Understanding how potassium channels fold and assemble to prevent heart rhythm problems

  This study is looking at how potassium channels in heart cells work and how certain genetic changes can cause heart rhythm problems like Long-QT and Brugada syndromes, with the goal of finding better ways to treat or prevent these issues for patients.

  NIH research University of Chicago · Chicago, United States · NIH-10989955

• Understanding how a specific protein affects heart rhythm problems

  This study is looking at a protein called B56α to see how it affects heart cell activity and sodium channels that help control heart rhythm, with the hope of finding new ways to help people with irregular heartbeats and reduce the risk of sudden cardiac issues.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-10943347

• Improving heart rhythm control using non-invasive techniques

  This study is looking at how a special technique called repetitive transcutaneous magnetic stimulation (TcMS) can help improve heart rhythm problems, especially for people who have frequent episodes of fast heartbeats, and it aims to find new ways to manage these issues better.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-10915675

• New method to treat heart rhythm problems in heart failure patients

  This study is testing a new, less invasive way to help people with chronic heart failure who have heart rhythm problems that don’t respond to medication, by targeting a specific group of nerves to improve their heart function and stability.

  NIH research University of Nebraska Medical Center · Omaha, United States · NIH-10908608

• Non-invasive imaging technique for mapping heart rhythm issues

  This study is testing a new, safe imaging method called Electromechanical Wave Imaging that uses ultrasound to create a 3D picture of your heart's electrical activity, helping doctors find the cause of heart rhythm problems more easily and without any radiation.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10826976

• Using AI and 4D Ultrasound to Improve Imaging of Heart Rhythm Disorders

  This study is exploring a new way to use advanced ultrasound and artificial intelligence to get clearer pictures of how your heart beats, which could help doctors better understand and treat heart rhythm problems like atrial fibrillation without needing invasive procedures.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10473146

Related topics

Quick answers

How many Cardiac Arrhythmia clinical trials are recruiting right now?

15, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United Kingdom (4 trials), Canada (3 trials), Italy (3 trials), Czechia (2 trials), United States (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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