Evaluating high power short duration RF for atrial fibrillation ablation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the safety and efficacy of pulmonary vein isolation using high power short duration radiofrequency energy in patients with paroxysmal or persistent atrial fibrillation. Participants will undergo catheter ablation with commercially approved devices and will be followed for 12 months to monitor the recurrence of atrial fibrillation and identify predictors of outcomes. The study plans to enroll at least 850 patients to ensure adequate statistical power for analyzing the primary endpoint, which focuses on the relationship between clinical characteristics and the effectiveness of the procedure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with paroxysmal/persistent AF who signed the informed consent
* Patients on active oral anticoagulation

Exclusion Criteria:

* Previous ablation for AF
* Patients with LVEF\<35%
* Women potentially pregnant
* Contraindications to X-ray exposure
* Congenital heart disease or cardiac surgery within 1 month

Where it's running

• Centre Cardiologique Du Nord
  Paris, France Recruiting
• Clinica Montevergine
  Mercogliano, Av, Italy Recruiting
• Maria cecilia Hospital
  Cotignola, Ra, Italy Recruiting
• Ospedale di Conegliano
  Conegliano, Tv, Italy Recruiting
• Università Politecnica delle Marche
  Ancona, Italy Recruiting
• Ospedale Civile di Asti
  Asti, Italy Recruiting

Study contacts

• Study coordinator: Giuseppe Stabile, MD
• Email: gmrstabile@tin.it
• Phone: +393488960534

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities

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• Identifying AF patients who may need more than standard ablation using Volta AF-Xplorer II

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• 4D intracardiac echocardiography to guide left atrial appendage occlusion procedures

  A new 4D ICE catheter is being tested alongside standard imaging to see if it can safely guide left atrial appendage occlusion procedures for adults with atrial fibrillation.

  Recruiting The Cleveland Clinic · Cleveland, Ohio · NCT07806890

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.