Condition

Brain Neoplasms clinical trials and research

• 17Clinical trials
• 1NIH research projects
• 1New in 30 days
• 16Countries

Newest Brain Neoplasms clinical trials

All recruiting trials (17)

• YN003 injection in glioma patients

  This phase 1 study tests whether YN003 injected IV is safe and tolerable for adults with recurrent or progressive glioma, and to explore how the drug behaves in the body and any early signs of activity.

  Recruiting at 2 sites Phase 1 Beijing Inno Medicine Co., Ltd. · Los Angeles, California and 4 other locations · NCT07929909

• Connectome-guided navigation for eloquent-area brain tumor surgery

  We’re testing whether using a patient’s brain network maps to guide tumor removal in eloquent areas helps preserve function better than standard tractography-guided surgery.

  Recruiting Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Beijing · NCT07657403

• Group occupational therapy program to help adults with primary brain tumours manage daily activities

  This program will try a six-week occupational therapy group to see if it helps adults with primary brain tumours on active treatment improve daily functioning and quality of life.

  Recruiting Royal College of Surgeons, Ireland · Dublin, Beaumont · NCT07426848

• Gadolinium-weighted MRI to better find brain metastases

  This will test a new MRI technique after gadolinium contrast to see if it finds more or smaller brain metastases in adults having a routine contrast brain MRI.

  Recruiting Region Stockholm · Stockholm, Solna · NCT07272616

• Fluorescence-guided suction monitoring to detect tumor tissue during brain surgery

  This trial will test a device that detects 5-ALA fluorescence in surgical suction to help surgeons find tumor tissue during adult glioma surgery.

  Recruiting University of Illinois Chicago · Chicago, Illinois · NCT07111182

• Home-based self-management and cognitive training for brain tumor survivors

  This trial will try a home-based cognitive coaching program to see if it improves thinking and quality of life for adults who survived non-glioblastoma brain tumors, with optional caregiver participation.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06930846

• Placement of an Ommaya reservoir during biopsy for brain tumor patients

  This study is testing whether placing a small device under the scalp during a brain tumor biopsy can help doctors collect fluid samples over time to better understand how the tumor is growing and responding to treatment.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT06322602

• Resection techniques for recurrent glioblastoma

  This study is testing different methods of mapping the brain during surgery for recurring glioblastoma to see which one helps patients keep their movement and speech abilities while removing as much of the tumor as possible.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06273176

• Guided meditation during radiation therapy for brain tumors

  This study tests if listening to guided meditation during radiation therapy can help reduce anxiety in patients with brain tumors.

  Recruiting University of Utah · Salt Lake City, Utah · NCT06165653

• Testing JYP0322 for ROS1 Fusion-Positive Solid Tumors

  This study is testing a new oral medication called JYP0322 to see if it can help people with certain types of advanced solid tumors that have a specific genetic change called ROS1 fusion.

  Recruiting Phase 1 Guangzhou JOYO Pharma Co., Ltd · Guangzhou, Guangdong · NCT06128148

• Comparing two surgical approaches for high-grade glioma patients

  This study is testing whether a more extensive surgical method for removing high-grade brain tumors helps patients live longer and feel better compared to a standard approach.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06118723

• Prognosis prediction for patients with cardiovascular and cerebrovascular diseases using multi-omics

  This study is trying to find out how different biological factors affect people with heart and brain blood vessel diseases to help doctors predict outcomes and personalize treatments for them.

  Recruiting First Affiliated Hospital Xi'an Jiaotong University · Xi'an, Shaanxi · NCT06001073

• Entrectinib treatment for patients with ROS1-positive cancers

  This study is testing if the drug entrectinib can help people with different types of cancers that have a ROS1 gene fusion, including adults and kids, to see if it works better than what’s currently available.

  Recruiting at 24 sites Phase 2/3 Cancer Research UK · Belfast and 26 other locations · NCT05770544

• Combination treatment for brain metastasis from ER+/HER-2- breast cancer

  This study is testing a new combination treatment of elacestrant and abemaciclib to see if it can help people with brain metastases from estrogen receptor-positive, HER-2 negative breast cancer.

  Recruiting at 78 sites Phase 1/2 Stemline Therapeutics, Inc. · Fullerton, California and 85 other locations · NCT05386108

• Investigating the role of platelets in brain tumors

  This study looks at how platelets might affect the growth and spread of brain tumors, especially gliomas, by collecting blood and tumor samples to better understand their interactions.

  Recruiting Fondation Ophtalmologique Adolphe de Rothschild · Paris · NCT05049148

• Using Amino Acid PET/MRI to Diagnose Brain Tumors

  This study is testing if using a special imaging technique that combines amino acid PET and MRI can help doctors better diagnose brain tumors in adults who need surgery or a biopsy.

  Recruiting Norwegian University of Science and Technology · Bergen and 2 other locations · NCT04111588

• Comparing awake craniotomy and general anesthesia for glioblastoma surgery

  This study is testing whether having brain surgery while awake is safer and more effective than having it under general anesthesia for people with glioblastoma in important areas of the brain.

  Recruiting at 5 sites Erasmus Medical Center · Ghent and 4 other locations · NCT03861299

NIH-funded research (1)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Using nanocages to deliver TGFb inhibitors for treating brain tumors

  This study is exploring a new way to treat glioblastoma, a tough type of brain cancer, by using tiny carriers to deliver a special treatment that helps boost the immune system's ability to fight the cancer, aiming to make current therapies work better and improve outcomes for patients.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11126743

Related topics

Quick answers

How many Brain Neoplasms clinical trials are recruiting right now?

17, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 16 countries. The most sites are in United States (8 trials), Belgium (4 trials), China (4 trials), Germany (3 trials), Netherlands (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 2, Phase 1/2: 1, Phase 2/3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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