Condition

Glioblastoma Multiforme of Brain clinical trials and research

• 10Clinical trials
• 6Countries

Newest Glioblastoma Multiforme of Brain clinical trials

All recruiting trials (10)

• Phase 1 safety and dose-finding of GLIX1 for adults with recurrent or progressive high-grade glioma

  This trial will test whether taking oral GLIX1 daily is safe, tolerable, and shows early anti-tumor activity in adults with recurrent or progressive high-grade glioma.

  Recruiting at 4 sites Phase 1 Tetragon Biosciences Ltd · Palo Alto, California and 3 other locations · NCT07464925

• Focused ultrasound to open the blood-brain barrier in adults with high-grade glioma on chemotherapy

  This trial tests whether focused ultrasound using the Next Generation Dome Helmet can safely open the blood-brain barrier in adults with glioblastoma who are receiving maintenance temozolomide chemotherapy.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · Toronto, Ontario · NCT07179328

• Adding ruxolitinib to standard radiation and temozolomide for newly diagnosed glioblastoma

  This trial will try whether adding the oral drug ruxolitinib to standard radiation and temozolomide helps adults newly diagnosed with glioblastoma.

  Recruiting at 2 sites Phase 2 Baptist Health South Florida · Miami, Florida and 1 other locations · NCT06991101

• GPC3-targeted CAR T cell therapy for recurrent GPC3-positive glioblastoma

  This study will try CAR T cells engineered to target GPC3 in adults with recurrent GPC3-positive glioblastoma during their planned surgery.

  Recruiting Phase 1 Baylor College of Medicine · Houston, Texas · NCT06815432

• Metabolic profiling of glioblastoma using advanced imaging techniques

  This study is testing new imaging techniques to see how glioblastoma tumors use energy and nutrients, which could help doctors understand the tumors better and improve treatment options.

  Recruiting at 2 sites Early Phase 1 Abramson Cancer Center at Penn Medicine · Philadelphia, Pennsylvania and 1 other locations · NCT06613841

• Comparing surgery and best treatment for recurrent glioblastoma

  This study is testing whether surgery or the best available treatment helps people with recurring glioblastoma feel better and live longer.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06283927

• Resection techniques for recurrent glioblastoma

  This study is testing different methods of mapping the brain during surgery for recurring glioblastoma to see which one helps patients keep their movement and speech abilities while removing as much of the tumor as possible.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06273176

• Comparing tumor resection and biopsy for high-grade glioma patients

  This study is testing whether removing a brain tumor or just taking a small sample helps older patients with high-grade gliomas live longer and feel better afterward.

  Recruiting at 6 sites Erasmus Medical Center · San Francisco, California and 7 other locations · NCT06146725

• Using omental tissue to treat recurrent glioblastoma

  This study is testing whether using a piece of fat from the abdomen can help improve treatment for patients with recurrent glioblastoma by delivering medication and immune cells more effectively to the tumor site.

  Recruiting Northwell Health · New York, New York · NCT05979064

• Comparing awake craniotomy and general anesthesia for glioblastoma surgery

  This study is testing whether having brain surgery while awake is safer and more effective than having it under general anesthesia for people with glioblastoma in important areas of the brain.

  Recruiting at 5 sites Erasmus Medical Center · Ghent and 4 other locations · NCT03861299

Related topics

Quick answers

How many Glioblastoma Multiforme of Brain clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (8 trials), Belgium (4 trials), Netherlands (4 trials), Germany (3 trials), Switzerland (3 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 3, Phase 2: 1, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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