Clinical trial Recruiting at 1 site Observational Ages 3 to 80

Prognosis prediction for patients with cardiovascular and cerebrovascular diseases using multi-omics

Official title: Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics (PROSPECT): a National, Multicenter, Retrospective-prospective, Cohort Study

Run by First Affiliated Hospital Xi'an Jiaotong University · NCT06001073 · Data updated 2026-11-12

This study is trying to find out how different biological factors affect people with heart and brain blood vessel diseases to help doctors predict outcomes and personalize treatments for them.

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Quick facts

Study typeObservational
Ages3 Years to 80 Years
SexAll
Enrollment25000 (estimated)
SponsorFirst Affiliated Hospital Xi'an Jiaotong University
Academic / other
Locations1 site (Xi'an, Shaanxi)
StatusRecruiting
StartedDecember 5, 2022
Main results expectedJune 30, 2028
Study endsDecember 31, 2028
Registry record updatedJuly 12, 2024
Trial IDNCT06001073 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients diagnosed with conditions such as coronary artery disease, arrhythmias, heart valve diseases, and other specified cardiovascular and cerebrovascular diseases.

Probably not a fit

Patients outside the age range of 3 to 80 years, pregnant or lactating women, and those unable to provide informed consent will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect clinical and biological specimen data from patients diagnosed with various cardiovascular and cerebrovascular diseases. By employing multi-omics technology, the study seeks to uncover the underlying pathogenic mechanisms of these diseases. The ultimate goal is to develop early predictive prognostic models that can inform individualized treatment strategies for affected patients. This research addresses the significant public health challenge posed by cardiovascular diseases and aims to enhance diagnosis and treatment options.

Why it matters

Potential benefit: If successful, this study could lead to more accurate prognostic models and personalized treatment plans for patients with cardiovascular and cerebrovascular diseases.

How similar studies have gone: While the use of multi-omics in cardiovascular research is gaining traction, this specific approach to prognosis prediction remains novel and largely untested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who are regularly visited and followed up in the appropriate patient; department.
* All patients met at least one of the following diagnostic criteria for cardiovascular and cerebrovascular diseases:
* coronary artery disease group;
* arrhythmia group;
* heart valve disease group;
* aortic dissection group;
* cardiac masses group;
* myocarditis group;
* hypertension group;
* cardiomyopathy group;
* structural heart disease group;
* ischemic cerebrovascular disease group;
* hemorrhagic cerebrovascular disease group;
* intracranial space occupying lesion group.

Exclusion Criteria:

* Age \<3 years or \>80 years old;
* Pregnant and lactating women;
* The patient declined to provide informed consent to participate in the study;
* None of the above was met, but the patient was temporarily unable to sign the informed consent form due to coma and other reasons, and no legal representative signed it instead. Depending on the patient's condition, the patient may not be able to regain consciousness and sign the informed consent form.

Where it's running

  • First Affiliated Hospital of Xian Jiantong University
    Xi'an, Shaanxi, China
    Recruiting

Study contacts

  • Principal investigator: Gouliang Li — First Affiliated Hospital Xi'an Jiaotong University
  • Study coordinator: Gouliang Li
  • Email: liguoliang_med@163.com
  • Phone: 13759982523

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.