Gadolinium-weighted MRI to better find brain metastases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective comparison enrolls adults with known or suspected brain metastases who are already scheduled for a clinical gadolinium-enhanced brain MRI. Each participant receives the routine contrast-enhanced MRI followed by an additional gadolinium-weighted sequence without increasing the contrast dose or overall scan time. Images from the novel sequence will be compared to standard MRI images to determine whether it improves detection of lesions. The observational study is conducted at Karolinska University Hospital in Solna, Sweden.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Scheduled for clinical brain MRI with gadolinium contrast
* Known or suspected brain metastases
* Able to provide informed consent
* Able to lie still for the duration of the MRI examination

Exclusion Criteria:

* Contraindications to MRI
* Known allergy or contraindication to gadolinium-based contrast agents
* Renal impairment (eGFR \< 30 mL/min/1.73m²)
* Pregnant or breastfeeding
* Inability to comply with study procedures

Where it's running

• Karolinska University Hospital
  Stockholm, Solna, Sweden Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.