Condition

Autoimmune Encephalitis clinical trials and research

• 14Clinical trials
• 5NIH research projects
• 8Countries

Newest Autoimmune Encephalitis clinical trials

All recruiting trials (14)

• Pregnant Women with Neuroimmune Diseases: A long-term follow-up study

  This study follows women with neuroimmune diseases and healthy controls through pregnancy and up to ten years to see how pregnancy affects disease activity and outcomes for both mother and baby.

  Recruiting Third Affiliated Hospital, Sun Yat-Sen University · Guangzhou, Guangdong · NCT07653984

• Identifying new autoantibodies and causes of autoimmune encephalitis

  This project looks for new autoantibodies and other disease features in adults with autoimmune encephalitis to help improve diagnosis and care.

  Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Rome, RM · NCT07477015

• ART5803 for people with anti-NMDAR encephalitis or anti-NMDAR autoantibody–linked psychiatric disease

  This will test whether ART5803, a one‑armed antibody, is safe and can help adults with anti‑NMDAR encephalitis or anti‑NMDAR autoantibody‑associated psychiatric symptoms.

  Recruiting Phase 2 Arialys Australia Pty Ltd · Seoul · NCT07093333

• Universal CD19/BCMA CAR T-cell therapy for relapsed or refractory neurological autoimmune diseases

  This will test whether a single infusion of universal CD19/BCMA CAR T-cells given after chemotherapy helps adults with relapsed or refractory neurological autoimmune diseases who have CD19- or BCMA-positive B cells.

  Recruiting Early Phase 1 Tianjin Huanhu Hospital · Tianjin · NCT06939166

• Using Calculus Bovis Sativus to treat adult encephalitis

  This study is testing a traditional Chinese medicine called Calculus Bovis Sativus to see if it can help adults with autoimmune encephalitis feel better.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06584045

• Identifying biomarkers for autoimmune diseases affecting the nervous system

  This study is trying to find specific markers in the blood of people with autoimmune diseases affecting the nervous system, like Multiple Sclerosis, to help with early diagnosis and better treatment options.

  Recruiting Tongji Hospital · Wuhan · NCT06502015

• Evaluating outcomes in patients with anti-LGI1 encephalitis

  This study is trying to see how patients with a specific type of autoimmune encephalitis, called anti-LGI1 encephalitis, do over time by looking at their symptoms and test results.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT06173076

• Evaluating brain glucose metabolism in autoimmune encephalitis patients

  This study is testing if a special brain scan can help doctors better understand how autoimmune encephalitis affects brain function in patients right before or shortly after they start treatment.

  Recruiting Assistance Publique - Hôpitaux de Paris · Paris · NCT06079294

• Using FDG-PET to diagnose autoimmune encephalitis

  This study is testing if brain scans can help doctors tell the difference between autoimmune encephalitis and other conditions like Alzheimer's disease.

  Recruiting at 2 sites University of Milano Bicocca · Udine, Friuli Venezia Giulia and 5 other locations · NCT06019975

• Understanding immune responses in autoimmune encephalitis and paraneoplastic neurological syndromes

  This study is trying to find specific markers in the blood and spinal fluid of people with autoimmune encephalitis and paraneoplastic neurological syndromes to help improve diagnosis and treatment options.

  Recruiting Hospices Civils de Lyon · Lyon · NCT05772611

• A platform for collecting health data on ME/CFS and Long Covid

  This study is trying to collect health information from adults with ME/CFS and Long Covid to help researchers better understand these conditions and improve future treatments.

  Recruiting Brain Inflammation Collaborative · Delafield, Wisconsin · NCT04806620

• Using CT103A cells to treat autoimmune diseases of the nervous system

  This study is testing if a new treatment using CT103A cells can help people with certain autoimmune diseases affecting the nervous system feel better.

  Recruiting Early Phase 1 Tongji Hospital · Wuhan, Hubei · NCT04561557

• Investigating Inebilizumab for NMDAR Encephalitis

  This study is testing if a new treatment called inebilizumab can help people with NMDAR encephalitis recover better than standard therapies or a placebo.

  Recruiting at 39 sites Phase 2 University of Utah · Birmingham, Alabama and 38 other locations · NCT04372615

• Evaluating Bortezomib for Severe Autoimmune Encephalitis

  This study is testing if bortezomib can help people with severe autoimmune encephalitis feel better by targeting the cells that produce harmful antibodies.

  Recruiting at 17 sites Phase 2 Jena University Hospital · München, Bavaria and 16 other locations · NCT03993262

NIH-funded research (5)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Identifying MRI markers of thinking problems in autoimmune brain inflammation

  A small study will look for MRI signs that relate to memory problems in people with autoimmune limbic encephalitis.

  NIH research Cleveland Clinic Lerner Com-Cwru · Cleveland, United States · NIH-11384749

• Autoimmune Encephalitis: finding new antibody targets to understand brain inflammation

  Researchers are studying people and animal models to discover new antibodies linked to autoimmune brain inflammation and what they mean for diagnosis and treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11305820

• Understanding how antibodies affect brain signaling in autoimmune encephalitis

  This study is looking at how certain antibodies in the body can affect brain function in people with autoimmune encephalitis, with the hope of finding new ways to help improve treatments for those living with this condition.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-10811827

• Identifying new antibody targets in autoimmune encephalitis and related conditions

  This study is looking at autoimmune encephalitis to find specific markers in the blood that could help doctors diagnose and treat patients better, especially those experiencing serious neurological and psychiatric symptoms.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-10783688

• How human antibodies affect brain signaling in autoimmune encephalitis

  This study is looking at how certain antibodies in the body affect brain function in people with autoimmune encephalitis, with the hope of finding new ways to help improve treatments for those dealing with this condition.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-10674739

Related topics

Quick answers

How many Autoimmune Encephalitis clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in China (6 trials), Italy (2 trials), United States (2 trials), France (2 trials), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 3, Early Phase 1: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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