Condition

Neuromyelitis Optica Spectrum Disorder clinical trials and research

• 11Clinical trials
• 20Countries

Newest Neuromyelitis Optica Spectrum Disorder clinical trials

All recruiting trials (11)

• Ravulizumab in Chinese adults with NMOSD

  This study tests ravulizumab in Chinese adults with NMOSD who are AQP4 antibody positive to see if it helps reduce relapses and is safe.

  Recruiting Phase 3 Alexion Pharmaceuticals, Inc. · Beijing and 9 other locations · NCT07557420

• Identifying biomarkers for autoimmune diseases affecting the nervous system

  This study is trying to find specific markers in the blood of people with autoimmune diseases affecting the nervous system, like Multiple Sclerosis, to help with early diagnosis and better treatment options.

  Recruiting Tongji Hospital · Wuhan · NCT06502015

• Using Calculus Bovis Sativus to treat inflammatory demyelinating diseases

  This study is testing if a traditional Chinese medicine called Calculus Bovis Sativus can help people with conditions like multiple sclerosis feel better and reduce inflammation.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT06474520

• Registry of patients with AQP4+ NMOSD treated with C5 inhibitors

  This study is collecting information from people with AQP4+ NMOSD who are being treated with C5 inhibitors to see how well these treatments work and how they affect daily life over five years.

  Recruiting at 23 sites Alexion Pharmaceuticals, Inc. · Washington D.C., District of Columbia and 32 other locations · NCT05966467

• Monitoring the safety of UPLIZNA in pregnant women with NMOSD

  This study is trying to see how safe the medication UPLIZNA is for pregnant women with Neuromyelitis Optica Spectrum Disorder (NMOSD) by tracking their pregnancies and outcomes over the next 10 years.

  Recruiting Amgen · Aurora, Colorado · NCT05909761

• Evaluating Inebilizumab for Children with Neuromyelitis Optica Spectrum Disorder

  This study is testing a new treatment called inebilizumab to see if it can help children with a specific type of neuromyelitis optica spectrum disorder feel better and stay safe during the treatment.

  Recruiting at 19 sites Phase 2 Amgen · La Jolla, California and 18 other locations · NCT05549258

• Ofatumumab for AQP4‑antibody positive neuromyelitis optica spectrum disorder

  This pilot will try ofatumumab, a human anti‑CD20 antibody, in adults with AQP4‑IgG positive NMOSD who have had recent relapses to see if it reduces relapses and is safe.

  Recruiting Phase 1/2 Tang-Du Hospital · Xi'an, Shaanxi · NCT05504694

• Evaluating satralizumab for children with neuromyelitis optica spectrum disorder

  This study is testing a new treatment called satralizumab to see if it helps children aged 2 to 11 with neuromyelitis optica spectrum disorder feel better and stay safe.

  Recruiting at 13 sites Phase 3 Hoffmann-La Roche · Denver, Colorado and 13 other locations · NCT05199688

• National registry for pediatric inflammatory brain diseases in Switzerland

  This study is collecting information on children with inflammatory brain diseases in Switzerland to see how to better diagnose and treat these conditions.

  Recruiting at 12 sites University of Bern · Aarau, Canton of Aargau and 12 other locations · NCT05017142

• Using CT103A cells to treat autoimmune diseases of the nervous system

  This study is testing if a new treatment using CT103A cells can help people with certain autoimmune diseases affecting the nervous system feel better.

  Recruiting Early Phase 1 Tongji Hospital · Wuhan, Hubei · NCT04561557

• Monitoring pregnancies in women with multiple sclerosis

  This study is trying to see how pregnancy affects women with multiple sclerosis and their babies, while also looking at treatments and breastfeeding.

  Recruiting at 48 sites Hospices Civils de Lyon · Amiens and 47 other locations · NCT03900221

Related topics

Quick answers

How many Neuromyelitis Optica Spectrum Disorder clinical trials are recruiting right now?

11, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 20 countries. The most sites are in China (7 trials), United States (4 trials), Argentina (3 trials), France (3 trials), Italy (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Early Phase 1: 1, Phase 1/2: 1, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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