Identifying MRI markers of thinking problems in autoimmune brain inflammation

Who could benefit from this research

What this research studies

Autoimmune limbic encephalitis (ALE) inflames the brain’s memory areas and often leaves lasting cognitive trouble. This project will use advanced MRI techniques to find brain changes that correspond with cognitive symptoms in ALE patients and compare them with healthy individuals. The goal is to identify markers that could guide treatment decisions about continuing or adjusting immunosuppression. The study is designed for a short-term funding period and focuses on translating MRI findings into clinically useful information for patients. Participants will undergo MRI scans and cognitive assessments as part of routine care under close supervision.

Why it matters

Where this research is happening

• Cleveland Clinic Lerner Com-Cwru
  Cleveland, United States Active

Researchers

• Principal investigator: Kunchok, Amy — Cleveland Clinic Lerner Com-Cwru
• Study coordinator: Kunchok, Amy

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.