Using FDG-PET to diagnose autoimmune encephalitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare brain FDG-PET imaging of patients diagnosed with autoimmune encephalitis against normal controls and patients with Alzheimer's disease. By retrospectively analyzing data and images from hospital records, the study seeks to identify specific patterns of brain metabolism associated with autoimmune encephalitis. Participants will have undergone brain imaging, cerebrospinal fluid analysis, and autoantibody testing as part of their clinical evaluation. The study will utilize statistical parametric mapping (SPM) for image analysis, with control data sourced from validated public databases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of autoimmune encephalitis according to clinical criteria
* Brain magnetic resonance imaging performed between clinical presentation and treatment
* Cerebrospinal fluid analysis performed between clinical presentation and treatment
* Brain FDG-PET performed between clinical presentation and treatment
* Autoantibodies testing performed between clinical presentation and treatment

Exclusion Criteria:

* Refusal to give consent for the study

Where it's running

• Fondazione IRCCS Mondino
  Pavia, Lombardy, Italy Recruiting
• Fondazione IRCCS San Gerardo dei Tintori
  Monza, Monza e Della Brianza, Italy Recruiting
• Azienda Sanitaria Universitaria Friuli Centrale
  Udine, Friuli Venezia Giulia, Italy Not yet recruiting
• IRCCS Ospedale Policlinico San Martino
  Genoa, Liguria, Italy Not yet recruiting
• Fondazione IRCCS Istituto Neurologico "Carlo Besta"
  Milan, Milano, Italy Not yet recruiting
• Ospedale San Paolo
  Milan, Milano, Italy Not yet recruiting

Study contacts

• Principal investigator: Simone Beretta, MD, PhD — University of Milano Bicocca
• Study coordinator: Simone Beretta, MD, PhD
• Email: simone.beretta@unimib.it
• Phone: +390392333568

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.