Understanding immune responses in autoimmune encephalitis and paraneoplastic neurological syndromes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to characterize the immune responses in patients diagnosed with autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS). It focuses on identifying specific autoantibodies in serum and cerebrospinal fluid, which can serve as biomarkers for these conditions. By analyzing the presence of these autoantibodies, the study seeks to improve diagnostic accuracy and treatment outcomes through appropriate immunotherapy. The research will involve genetic and immunological testing to better understand the underlying mechanisms of these rare neuroimmune disorders.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient with neurological disorder
* Patient with antibodies or not in sera or CSF

Exclusion Criteria:

\- No available clinical data

Where it's running

• Centre de référence des syndromes neurologiques paranéoplasiques et encéphalites autoimmunes
  Lyon, France Recruiting

Study contacts

• Study coordinator: Jerome HONNORAT, MD
• Email: jerome.honnorat@chu-lyon.fr
• Phone: +33 4 72 35 78 06

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.