Condition

Alcohol Consumption clinical trials and research

• 10Clinical trials
• 44NIH research projects
• 4Countries

Newest Alcohol Consumption clinical trials

All recruiting trials (10)

• Probenecid to reduce alcohol craving and consumption

  This trial will test whether taking daily probenecid (2 g/day) reduces craving and drinking in adults with moderate-to-severe alcohol use disorder.

  Recruiting Phase 2 Brown University · Providence, Rhode Island · NCT07118618

• Mentor Mothers+ support program for pregnant and breastfeeding people who use alcohol

  This trial will test whether Mentor Mothers+—brief motivational sessions delivered by trained local mothers—can reduce alcohol use and improve PrEP or ART adherence among pregnant and breastfeeding people who use alcohol in Cape Town.

  Recruiting University of California, Los Angeles · Cape Town, Western Cape and 1 other locations · NCT06962592

• New blood test to help identify and track depression and early schizophrenia

  This project will try a new blood test to see if it can identify and track depression or early schizophrenia in adults receiving psychiatric care.

  Recruiting Fraser Health · New Westminster, British Columbia · NCT06856161

• Examining alcohol use in romantic relationships

  This study is testing how drinking alcohol affects couples' relationships by having them drink either alcohol or non-alcoholic drinks and then answer questions about their relationship over time.

  Recruiting Carnegie Mellon University · Pittsburgh, Pennsylvania · NCT06822257

• Telehealth BASICS for college students who drink heavily

  This study tests whether a telehealth version of BASICS can help college students who drink hazardously compare to in-person BASICS and usual treatment.

  Recruiting University of Southern California · Houston, Texas · NCT06774300

• Understanding blood markers for alcohol consumption

  This study is testing if a blood marker called PEth can help us understand how much and how often people drink alcohol by looking at their blood after they consume alcohol in a lab.

  Recruiting at 2 sites The University of Texas Health Science Center at San Antonio · Denton, Texas and 1 other locations · NCT06747364

• Social influence on drinking among young adults

  This test will see if being around same-sex platonic friends changes how much young adults (21–28) drink during lab sessions and in daily life.

  Recruiting University of Southern California · Los Angeles, California · NCT06627803

• Effects of Mavoglurant on Alcohol Craving and Drinking in Heavy Drinkers

  This study is testing if a new drug called mavoglurant can help heavy drinkers with Alcohol Use Disorder reduce their cravings and drinking.

  Recruiting at 2 sites Phase 1 Yale University · New Haven, Connecticut and 1 other locations · NCT06136195

• Tailored interventions for harmful alcohol and drug use in hospital patients

  This study is testing whether personalized support for patients with harmful alcohol and drug use in the hospital can lead to better health outcomes compared to standard care.

  Recruiting Oslo University Hospital · Oslo · NCT04957628

• Exploring the health journeys of older adults with alcohol-related issues

  This study looks at how older adults over 60 with alcohol-related problems do after being hospitalized, to see if short treatments help them better than younger people.

  Recruiting Helse Stavanger HF · Stavanger · NCT04164940

NIH-funded research (newest 40 of 44)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Nicotine's effect on drinking sweetened alcoholic drinks

  This project looks at whether nicotine makes people drink more sweetened alcoholic drinks, especially among people who smoke or drink heavily.

  NIH research University of Nebraska Lincoln · Lincoln, United States · NIH-11525854

• Discounted rideshares, alcohol use, and driving behavior

  This trial gives some adults discounted rideshare trips to find out whether easier access to rides changes how often they drive after drinking, how much they drink, and how they get around.

  NIH research Yale University · New Haven, United States · NIH-11467861

• Alcohol use patterns around the legal drinking age in young adults

  This project follows 20-year-olds as they approach and reach legal drinking age to learn how drinking contexts and consequences change over time.

  NIH research University of Missouri-Columbia · Columbia, United States · NIH-11416601

• Technology-based tools to boost HIV viral suppression for people who drink alcohol in Florida

  A Florida team is testing digital tools and an alcohol biosensor to help people with HIV who drink reduce alcohol use and achieve better HIV control.

  NIH research University of Florida · Gainesville, United States · NIH-11402219

• Tracking how stress affects brain dynamics and drinking behavior

  A study at Yale will use brain imaging and computer models to see how stress-related brain activity relates to risky drinking in adults.

  NIH research Yale University · New Haven, United States · NIH-11401939

• ASPIRE to Change: text-message peer support to reduce risky drinking among non-college young adults

  A texting program called ASPIRE helps non-college young adults, aged 18–25, cut back on hazardous drinking by using peer support and environmental tips.

  NIH research Stanford University · Stanford, United States · NIH-11397017

• Understanding how a liver hormone (FGF21) is controlled during alcohol use

  A study in people with alcohol-related liver disease explores how inflammation in the liver affects a key hormone (FGF21) and whether this process can be targeted to reduce alcohol use and liver damage.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11390965

• How different cannabis types (THC vs CBD) affect drinking

  This work looks at whether using cannabis with different mixes of THC and CBD changes alcohol drinking in people who regularly use both substances.

  NIH research Brown University · Providence, United States · NIH-11389505

• Ketone supplement to reduce drinking in alcohol use disorder

  A ketone drink is being tested to help adults with alcohol use disorder drink less and feel better between cravings.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11384232

• Light alcohol use and stroke care: could small amounts help brain blood vessels

  A study explores whether very light alcohol consumption could help people at risk for ischemic stroke by promoting brain blood vessel growth and healing.

  NIH research Louisiana State Univ Hsc Shreveport · Shreveport, United States · NIH-11369534

• Chronic Alcohol Use and Lung Immune Defense in Pneumonia Risk

  A study to understand how long-term heavy drinking changes lung immune cells and makes pneumonia more likely, with a focus on how inflammatory molecules like hyaluronic acid influence this process.

  NIH research Emory University · Atlanta, United States · NIH-11367253

• Optimizing Social Media Messages to Help Young Women Understand Breast Cancer Risk from Alcohol

  A study will test how to craft social media messages that make young adult women aware of how alcohol can raise breast cancer risk and encourage healthier choices.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11337732

• Alcohol-related blood markers and knee osteoarthritis risk

  This project will use alcohol-related blood metabolites in adults to find links between drinking patterns and future knee osteoarthritis risk.

  NIH research University of Connecticut Sch of Med/dnt · Farmington, United States · NIH-11310808

• Investigating how cannabinoids affect alcohol use and gut health.

  This study is looking at how THC, a compound in cannabis, affects how much alcohol people drink and how both substances might influence gut health and brain function, helping to clear up some mixed messages from previous research.

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11308166

• How brain immune signals and the brain’s scaffolding influence heavy drinking

  This work looks at whether immune activity in brain support cells changes the brain’s extracellular matrix and promotes heavier drinking, with implications for people who drink excessively or have alcohol use disorder.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11295481

• Biochemical and genetic factors that drive heavy drinking

  Testing whether blocking interferon signaling can lower excessive alcohol drinking and help people with alcohol-use problems.

  NIH research University of Texas at Austin · Austin, United States · NIH-11295369

• Reducing Alcohol Use with a telehealth couples approach for sexual and gender minority couples living with HIV

  A telehealth program tests a short couples-based approach to help sexual and gender minority couples, where one partner has HIV, reduce unhealthy drinking.

  NIH research Brown University · Providence, United States · NIH-11241818

• Brain network patterns linked to risk for hazardous drinking

  We are looking at brain activity in teens and young adults to find patterns that signal a higher risk of hazardous drinking and whether gentle brain stimulation can change those patterns.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11238060

• How liver inflammation may change drinking through the hormone FGF21

  This project looks at whether liver inflammation cuts levels of the hormone FGF21 and in turn makes people drink more and worsens alcohol-related liver disease.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11195681

• Text-message peer coaching to reduce risky drinking in young adults not in college

  This project compares a peer-support text messaging program and a cognitive-behavioral text program to help 18–25-year-old non-college young adults cut down on hazardous drinking.

  NIH research Stanford University · Stanford, United States · NIH-11192341

• How the brain's stress responses relate to heavy drinking

  This project will measure how changing brain activity during stress relates to drinking habits in adults.

  NIH research Yale University · New Haven, United States · NIH-11168699

• How long-term drinking changes key immune blood cells

  This project looks at how chronic alcohol use alters monocytes (a type of immune cell) and their bone marrow precursors in people who drink heavily.

  NIH research University of Kentucky · Lexington, United States · NIH-11160885

• Technology to reduce drinking and improve HIV viral suppression in Florida

  This project uses apps, surveys, and a wearable alcohol sensor to help people with HIV in Florida who drink alcohol reduce drinking and keep their HIV virus suppressed.

  NIH research University of Florida · Gainesville, United States · NIH-11137611

• How insurance rules about intoxication affect drinking and injury care

  This project looks at whether state insurance laws that let insurers deny coverage for alcohol-related injuries change people's drinking, blood-alcohol testing after injury, and related outcomes.

  NIH research State University of New York at Albany · Albany, United States · NIH-11127765

• Understanding How Alcohol Affects Heart Health at a Molecular Level

  This project explores how drinking alcohol changes our body's molecules and how those changes might lead to heart disease.

  NIH research Boston University Medical Campus · Boston, United States · NIH-11105792

• How chronic alcohol use affects immune cells and their function

  This study looks at how long-term heavy drinking affects certain immune cells in the body, using monkeys to help us understand what happens in humans, with the goal of finding better ways to help people who have struggled with alcohol use.

  NIH research University of Kentucky · Lexington, United States · NIH-11097778

• Light Alcohol and Stroke Recovery

  This research explores how light alcohol consumption might help the brain recover after an ischemic stroke.

  NIH research Louisiana State Univ Hsc Shreveport · Shreveport, United States · NIH-11088296

• Understanding how liver inflammation affects alcohol consumption and liver disease

  This study is looking at how liver inflammation affects how your body processes alcohol and aims to find new ways to help people with alcohol use issues by focusing on a protein called FGF21.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-11048195

• How THC affects alcohol consumption and brain reward systems

  This study is looking at how using THC from cannabis affects how much alcohol people drink and how it impacts the brain's reward system, so if you're curious about how these two substances interact, this research might be for you!

  NIH research University of Colorado Denver · Aurora, UNITED STATES · NIH-11037923

• Exploring how alcohol consumption affects the risk of knee osteoarthritis

  This study is looking at how drinking alcohol might affect the chances of getting knee osteoarthritis, a condition that causes joint pain, and it’s for people who want to understand how their drinking habits could relate to their knee health.

  NIH research University of Connecticut Sch of Med/dnt · Farmington, United States · NIH-11036509

• Understanding brain changes related to alcohol addiction

  This study looks at how specific parts of the brain change when someone keeps drinking alcohol even when it causes problems, and it aims to help us understand addiction better so we can find new ways to treat it.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11030760

• Investigating how alcohol affects brain cell interactions and structure

  This study is looking at how drinking a lot of alcohol affects the brain's support system and immune responses, using mice to see if these changes might influence how much they drink, which could help us understand more about alcohol use disorders.

  NIH research Virginia Commonwealth University · Richmond, United States · NIH-11014434

• Using text messaging to help young adults reduce harmful drinking

  This study is looking for young adults aged 18 to 25 who want to cut back on drinking, and it will test a new program that uses text messages to offer support from friends and help change drinking habits, compared to a standard approach.

  NIH research Stanford University · Stanford, United States · NIH-10980286

• How hormones affect alcohol use and fear responses

  This study is looking at how alcohol use disorder and post-traumatic stress disorder affect each other in veterans, and it wants to see how a hormone called FGF21 might play a role in drinking habits and dealing with fear, all to find better ways to help those who are struggling with both conditions.

  NIH research Iowa City VA Medical Center · Iowa City, United States · NIH-10975914

• Using technology to help reduce alcohol use and improve HIV treatment in Florida

  This study is looking for people living with HIV who drink alcohol to understand how drinking affects their health and treatment, and it will involve surveys and a small group using a wrist device to track their drinking for a month.

  NIH research University of Florida · Gainesville, United States · NIH-10897096

• Understanding how stress affects alcohol consumption and brain function

  This study is looking at how stress affects drinking habits by checking brain activity, and it's designed for people who want to understand how stress might lead to risky drinking behaviors.

  NIH research Yale University · New Haven, United States · NIH-10891122

• Effects of chronic alcohol use on immune cells

  This study looks at how long-term heavy drinking impacts immune cells in the body, using monkeys to help us understand why people who drink a lot might get sick more often and have a harder time healing.

  NIH research University of Kentucky · Lexington, United States · NIH-10890648

• Investigating brain neurons that influence alcohol consumption

  This study is looking at how certain brain cells in the central amygdala influence drinking habits and feelings of reward, with the goal of finding new ways to help people who struggle with alcohol use.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10877062

• How insurance laws affect alcohol consumption and related health outcomes

  This study looks at how certain insurance laws might affect how much people drink and their health by making doctors hesitant to check blood alcohol levels, and it aims to find ways to improve healthcare for those dealing with alcohol-related problems.

  NIH research State University of New York at Albany · Albany, United States · NIH-10867113

• Improving alcohol consumption measurement for HIV-affected youth in Africa

  This study is looking to improve how we understand alcohol use among young people living with HIV in Zambia by using a special urine test that gives a more accurate picture than just asking them about their drinking, so we can help them get the support they need for better health.

  NIH research Columbia University Health Sciences · New York, United States · NIH-10834164

Related topics

Quick answers

How many Alcohol Consumption clinical trials are recruiting right now?

10, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 4 countries. The most sites are in United States (6 trials), Norway (2 trials), South Africa (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 1, Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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