NIH-funded research R01 grant

Understanding how stress affects alcohol consumption and brain function

Official title: Tracking brain dynamics of the acute stress response and neurocognitive mechanisms of chronic alcohol consumption

Funded at Yale University · NIH-10891122 · Data updated 2026-11-12

This study is looking at how stress affects drinking habits by checking brain activity, and it's designed for people who want to understand how stress might lead to risky drinking behaviors.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2029
Funding year2024
Award (this year)$711,808
NIH project number1R01AA031072-01A1
Project IDNIH-10891122 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults aged 21 and older who experience issues related to alcohol consumption or stress.

Less likely to help

Patients who do not consume alcohol or are not affected by stress-related drinking behaviors may not benefit from this research.

What this research studies

This research investigates the relationship between stress responses and alcohol consumption by examining brain dynamics. It aims to develop new biomarkers that can predict how stress influences drinking behavior and cognitive processes related to alcohol use. By using advanced machine learning techniques and functional MRI data, the study will analyze brain activity patterns in response to stress and how these patterns change over time. The goal is to identify specific brain responses that can help understand and potentially intervene in risky drinking behaviors.

Why it matters

Potential benefit: If successful, this research could lead to better interventions for individuals struggling with alcohol use disorder by targeting stress-related brain mechanisms.

How similar studies have gone: Previous research has shown promise in using brain imaging and machine learning to understand the relationship between stress and alcohol use, indicating that this approach could yield valuable insights.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Goldfarb, Elizabeth — Yale University
  • Study coordinator: Goldfarb, Elizabeth

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.