Understanding How Alcohol Affects Heart Health at a Molecular Level
Official title: Trans-omic Analysis of Alcohol Consumption and its Relation to Cardiovascular Disease
Funded at Boston University Medical Campus · NIH-11105792 · Data updated 2026-11-12
This project explores how drinking alcohol changes our body's molecules and how those changes might lead to heart disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2021 |
| Project end | April 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $538,996 |
| NIH project number | 5R01AA028263-05 |
| Project ID | NIH-11105792 on NIH RePORTER |
Who could benefit from this research
✓Could help
This research primarily involves analyzing existing biological data from individuals with varying alcohol consumption habits and cardiovascular disease outcomes.
✕Less likely to help
Patients not interested in the molecular links between alcohol and heart disease may not find direct personal benefit from this specific research.
What this research studies
We know that alcohol consumption can impact heart health, and this project aims to uncover the precise molecular pathways involved. Researchers will use advanced technologies to look at many different biological markers, including DNA changes, gene activity, proteins, and metabolites, in relation to alcohol intake. By studying these 'omics' data, we hope to identify specific molecular changes that link alcohol consumption to conditions like coronary heart disease and stroke. This deeper understanding could help us develop new strategies for preventing heart problems related to alcohol.
Why it matters
Potential benefit: If successful, this work could lead to new ways to predict and prevent cardiovascular disease in people who consume alcohol.
How similar studies have gone: While the general link between alcohol and cardiovascular disease is known, this project uses a novel 'trans-omic' approach to identify specific molecular pathways, building on previous work in individual omics fields.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Liu, Chunyu — Boston University Medical Campus
- Study coordinator: Liu, Chunyu
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.