How THC affects alcohol consumption and brain reward systems

Effects of THC on Alcohol Consumption and Neural Correlates of Reward

NIH-funded research University of Colorado Denver · NIH-11037923

This study is looking at how using THC from cannabis affects how much alcohol people drink and how it impacts the brain's reward system, so if you're curious about how these two substances interact, this research might be for you!

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11037923 on NIH RePORTER

What this research studies

This research investigates the effects of THC, the active component in cannabis, on alcohol consumption and the brain's reward systems. It aims to understand how simultaneous use of THC and alcohol influences drinking behavior and the underlying neural mechanisms. By examining the interaction between THC and alcohol, the study will explore whether THC increases or decreases the desire to consume alcohol. Participants will be involved in laboratory assessments to measure their responses to alcohol after THC exposure.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who consume both alcohol and cannabis.

Not a fit: Patients who do not use alcohol or cannabis may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment of alcohol use disorders, particularly in individuals who also use cannabis.

How similar studies have performed: Previous research has shown mixed results regarding the effects of THC on alcohol consumption, indicating that this area is still being explored and may yield novel insights.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.