Mentor Mothers+ support program for pregnant and breastfeeding people who use alcohol

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The Mentor Mothers+ pilot is a randomized controlled trial enrolling 100 pregnant people who reported alcohol use, recruited during antenatal care at clinics in Saldanha Bay, Cape Town. Participants are randomized to receive either the MM+ intervention—brief individual motivational interviewing sessions delivered by trained mentor mothers who previously reduced alcohol use and are on PrEP or ART—or an enhanced HIV attention control. Primary and secondary outcomes are measured at six months, with alcohol use assessed by phosphatidylethanol (PEth) and PrEP/ART continuation by urine tenofovir levels. The study examines feasibility and acceptability of adapting the evidence-based mentor mother model to reduce alcohol use while supporting HIV prevention and treatment in a high-burden community.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* • ≥ 16 years;

  * Pregnancy confirmed;
  * reported alcohol use during pregnancy (in last 2 months);
  * lives within 20 kilometers of the study facility;
  * able and willing to consent to study participation.

Exclusion Criteria:

* Individuals not meeting the above criteria will be excluded.

Where it's running

• Saldanha Bay Clinics
  Saldanha Bay, Western Cape, South Africa Recruiting
• Saldanha Bay Municipality Clinic
  Cape Town, Western Cape, South Africa Not yet recruiting

Study contacts

• Study coordinator: Dvora L Joseph Davey, PhD
• Email: dvoradavey@ucla.edu
• Phone: 310-701-1526

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.