NIH-funded research NIH-funded research

Nicotine's effect on drinking sweetened alcoholic drinks

Official title: Nicotine-enhancement of sweetened alcohol consumption: A behavioral economic evaluation

Funded at University of Nebraska Lincoln · NIH-11525854 · Data updated 2026-11-12

This project looks at whether nicotine makes people drink more sweetened alcoholic drinks, especially among people who smoke or drink heavily.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Lincoln
NIH-funded
Lab location1 site (Lincoln, United States)
Project startSeptember 19, 2025
Project endFebruary 28, 2029
Funding year2026
Award (this year)$191,583
NIH project number5P20GM130461-08
Project IDNIH-11525854 on NIH RePORTER

Who could benefit from this research

Could help

Adults who currently use nicotine (for example, smokers) and also drink alcohol frequently or have alcohol use disorder, and who can attend in-person visits, are the ideal participants.

Less likely to help

People who do not use nicotine, rarely drink alcohol, or cannot travel to the study site are unlikely to get direct benefit from this work.

What this research studies

If you take part, you'll come to lab sessions where researchers will offer alcoholic drinks that are sweetened in different ways and measure how much you choose to drink and how intoxicated you feel. The team will compare people who use nicotine with people who do not to see whether nicotine increases the appeal or value of sweetened alcohol. They will use behavioral economic methods to track choices and drinking amount across conditions, including sugar and noncaloric sweeteners. The aim is to understand why smoking and heavy drinking often occur together.

Why it matters

Potential benefit: If successful, this work could help design better strategies to reduce heavy drinking and smoking by revealing how nicotine and sweeteners combine to increase alcohol use.

How similar studies have gone: Prior studies show nicotine can boost the appeal of other rewards and that sweetened alcohol increases drinking and intoxication, but combining nicotine's effects with sweetened alcohol in people with alcohol problems remains incompletely explored.

Where this research is happening

  • University of Nebraska Lincoln
    Lincoln, United States
    Active

Researchers

  • Principal investigator: Barrett, Scott — University of Nebraska Lincoln
  • Study coordinator: Barrett, Scott

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.