Sponsor or institution

Clinical trials and research at University of North Carolina, Chapel Hill

• 96Clinical trials
• 13Countries

Newest trials

All recruiting trials (96)

• Light color therapy to help chronic pain

  This small crossover study tests whether colored light (S-cone chromatic light) can reduce pain in adults with fibromyalgia or chronic widespread pain compared with white light over two 7-day periods.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07825792

• Personalized PandA-tACS for Antenatal Depression

  This study tests whether a single personalized brain stimulation session can help pregnant people with depression more than a standard or sham stimulation.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07799480

• Melanin-Adjusted Blood Oxygen Sensor in ICU Patients

  This study tests a new pulse oximeter that adjusts for skin pigment to see if it gives accurate oxygen readings in ICU patients.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07799454

• Daily Upgrade: Can an essential amino acid supplement help active women improve body composition and metabolism?

  This study tests whether Daily Upgrade EAA+ helps healthy, active women by comparing it with whey protein and placebo before HIIT, and by using it daily for three weeks with twice-weekly HIIT workouts.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07792603

• Potassium-Competitive Acid Blockers in Barrett’s Esophagus on PPI Therapy

  This study tests whether vonoprazan, a potassium-competitive acid blocker, can better reduce acid reflux in adults with nondysplastic Barrett’s esophagus who are already taking a daily PPI.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07788742

• Long-Term Look at Long COVID after COVID-19

  Researchers will see how common Long COVID is and how symptoms stick around over time in adults who had COVID-19, using questionnaires and saliva samples to look for biological clues.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07781501

• See if exemestane helps PMOS patients ovulate compared with placebo

  This study tests whether daily exemestane can help women with PMOS/PCOS ovulate better than a placebo.

  Recruiting Phase 1 University of North Carolina, Chapel Hill · Raleigh, North Carolina · NCT07706374

• AI ultrasound tool to estimate fetal weight before delivery

  A AI-enabled ultrasound test is being tried in 1,000 pregnant people to see how accurately it can predict fetal weight compared with standard specialist measurements.

  Recruiting at 2 sites University of North Carolina, Chapel Hill · New Orleans, Louisiana and 5 other locations · NCT07661433

• IAP086 first-in-human single-dose safety study in people with HIV on ART

  This first-in-human trial tests a single dose of IAP086 to see if it is safe and tolerable in adults with HIV who are on stable antiretroviral therapy.

  Recruiting at 2 sites Phase 1 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 1 other locations · NCT07596888

• Upadacitinib for Eosinophilic Esophagitis in adults not responding to standard therapy

  This study tests whether upadacitinib, taken with topical corticosteroids, can reduce disease activity in adults with eosinophilic esophagitis who still have symptoms.

  Recruiting Phase 2 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 1 other locations · NCT07588568

• Early screening for sleep-disordered breathing in kids at the dentist

  This study tests whether a simple kid-friendly questionnaire can flag risk for sleep-disordered breathing in children aged 8–13 when checked during a dental visit.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07581938

• Brief, breath-focused ACT for adults with chronic cough

  This pilot test checks if a short, breath-control-oriented Acceptance and Commitment Therapy program is doable, acceptable, and safe for adults who have chronic cough.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07566117

• CARED: Rapid single-session combination of brain stimulation and therapy for depression

  This study will see if a single-session combo of psychotherapy, intermittent theta-burst TMS (iTBS), and active versus sham tACS helps adults with treatment-resistant major depressive disorder.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07507370

• Three-stage CGM integration program for older adults with insulin-dependent diabetes

  A program with three CGM-focused training sessions is being tested to see if it helps older adults using insulin wear CGMs more and manage their glucose better compared with standard CGM training.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07463209

• How a menthol cigarette ban, with or without a quit-smoking campaign, changes what people buy

  This trial tests whether banning menthol cigarettes, either alone or paired with a quit-smoking campaign, changes purchasing behavior among adults 21 and older who currently smoke menthol cigarettes.

  Recruiting University of North Carolina, Chapel Hill · Raleigh, North Carolina · NCT07458607

• Omega-3 supplement with special anti-inflammatory ingredients for chronic TMD pain

  This study tests whether a marine lipid supplement rich in SPM precursors can reduce facial pain in adults with chronic TMD compared with a placebo over 8 weeks.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07437313

• Healthful foods and caregiver training to support early learning in Guatemalan children

  This trial tests whether a fortified porridge plus caregiver coaching help 2-year-old children in rural Guatemala develop better neurodevelopment skills, alone or together.

  Recruiting University of North Carolina, Chapel Hill · Coatepeque, Departamento de Quetzaltenango · NCT07383428

• Added-sugar warning labels and weight bias

  This test sees if added-sugar warning labels on sugary drinks change weight bias and beliefs about who is responsible for body weight among adults who regularly buy sugary drinks.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07346001

• Over-the-counter pain medicine comparison for period cramps in women with Crohn's disease

  This pilot will test whether ibuprofen or acetaminophen relieves period cramps more effectively and safely for women aged 18–44 who have Crohn's disease in remission.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07337902

• Two approaches to repeat eyelid surgery for post-operative trichiasis

  This project will try whether the newer Bevel-Rotate Advancement Procedure (B-RAP) or the standard Bilamellar Tarsal Rotation (BLTR) gives better results for people in Tanzania who need repeat surgery for post-operative trachomatous trichiasis.

  Recruiting at 2 sites University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 1 other locations · NCT07322302

• Adolescent Mental Health Parenting Program for Teens and Parents (AMP-CARE)

  A parent-training program is being tested to see if it helps parents feel more confident in parenting teens and to improve their understanding of teen development and mental health.

  Recruiting at 2 sites University of North Carolina, Chapel Hill · Cary, North Carolina and 1 other locations · NCT07303062

• Added-sugar warning labels on sugary drinks

  This study will test whether added-sugar warning labels on sugary drinks make adults who drink these beverages buy less added sugar.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07294053

• Colored-light pain relief and brain mapping in chronic musculoskeletal pain

  This trial will test whether showing different colored lights to the eyes can reduce pain and change brain activity in adults with chronic musculoskeletal pain compared with healthy, age- and sex-matched controls.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07245303

• Zymfentra (infliximab-dyyb) real-world cohort

  This project will see if Zymfentra (infliximab-dyyb) reduces symptoms over one year in adults with Crohn's disease, ulcerative colitis, or indeterminate colitis who are starting or switching to the drug as part of routine care.

  Recruiting at 11 sites University of North Carolina, Chapel Hill · New Haven, Connecticut and 10 other locations · NCT07237516

• Digital (Bolster) support for caregivers of young people with early psychosis in North Carolina

  This pilot will try the Bolster mobile app to reduce caregiver stress and improve family communication for North Carolina caregivers of young adults with early psychosis.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07225179

• Comparing phrenic-sparing and interscalene nerve blocks for shoulder surgery in people with obesity

  This trial tests whether a phrenic-sparing nerve block, compared with the standard interscalene block, lowers early breathing problems after shoulder surgery in adults with obesity and whether a quick breathing-strength test (MIP) helps predict who is at higher risk.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07216820

• COMPARE — Newer IBD treatments in children

  This project compares the safety and effectiveness of newer IBD medicines for children with Crohn's disease or ulcerative colitis who did not respond to anti‑TNF treatment.

  Recruiting at 4 sites University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 3 other locations · NCT07198113

• Recovering sleep after a car crash

  This pilot will test whether four remote sessions of brief behavioral treatment for insomnia (BBTI) help people recently seen in the ER for a motor vehicle crash who are at high risk for PTSD and depression.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07196332

• Caring for the Carer: cognitive behavioral therapy support for caregivers of people who experienced psychosis

  This program will try a 20-session cognitive behavioral therapy to see if it is acceptable, feasible, and helps wellbeing for caregivers of people who have experienced psychosis.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07167641

• Changing brain rhythms to help hand movement after stroke

  This study will test whether short sessions of non-invasive brain stimulation to either the motor or visual brain can strengthen brain-to-muscle signals and improve hand-squeezing performance in people with chronic stroke and hand weakness.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07121582

• Once-daily intrapleural enzyme treatment for complicated pleural infections

  This will see if giving tPA and DNase once a day through a chest tube works as well as giving them twice a day for people with complicated pleural infections.

  Recruiting at 11 sites Phase 4 University of North Carolina, Chapel Hill · Little Rock, Arkansas and 10 other locations · NCT07095361

• Mapping sensations from spinal cord stimulation in people with chronic pain

  This project tries to identify the sensations spinal cord stimulation produces and see how those sensations change when stimulation settings are adjusted in adults receiving SCS for chronic pain.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07095036

• Helping rural toddlers on the autism spectrum start services sooner

  This project will test whether virtual Family Navigation helps toddlers under 4 in rural North Carolina with a new or pending autism diagnosis start community early-intervention services sooner and improves child development and caregiver well-being.

  Recruiting University of North Carolina, Chapel Hill · Carrboro, North Carolina · NCT07086781

• Stress patterns and anhedonia during adolescence

  We will see if combining brain scans, stress hormones, and heart-rate measures can identify patterns linked to developing anhedonia in 13–15-year-olds.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT07040449

• Focal Mass Drug Administration to Help Protect Pregnant Women from Malaria

  This pilot tests whether giving a single or ongoing dose of dihydroartemisinin-piperaquine to household members of pregnant women can reduce malaria in pregnancy, especially when care access is limited.

  Recruiting Early Phase 1 University of North Carolina, Chapel Hill · Kasese · NCT07021430

• Omega‑3 metabolite increase after SPM Active® supplementation in adults with obesity

  This test will see if taking 2 g/day of SPM Active® for 12 weeks raises specific omega‑3 derivatives and improves burnout, life satisfaction, and sleep in adults aged 45–60 with obesity.

  Recruiting University of North Carolina, Chapel Hill · Kannapolis, North Carolina · NCT06991296

• Understanding how anxiety affects substance use in adolescents

  This study is trying to see how anxiety affects substance use in kids aged 12-14 by looking at their brain activity and stress responses.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06977178

• BXCL501 given shortly after a car crash to reduce acute stress and later PTSD symptoms

  This will test whether a short course of BXCL501 sublingual film given in the emergency department after a motor vehicle collision can reduce acute stress symptoms and lower the chance of developing PTSD in high‑risk adults.

  Recruiting at 2 sites Phase 2 University of North Carolina, Chapel Hill · Jacksonville, Florida and 2 other locations · NCT06943404

• Measuring microplastic exposure in patients using clear aligners

  This study is trying to see how clear aligners might affect the levels of microplastics in the saliva and urine of orthodontic patients over time.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06934603

• Immersive physical therapy for NICU babies

  This project will try immersive physical and occupational therapy approaches with parents and very preterm infants (born before 29 weeks) to see if they lower parental stress and help parents meet their infants' needs.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06927037

• Resilience versus physical activity to improve early childhood educators' well-being

  This project will test whether a remote resilience program or a remote physical activity program helps early childhood education staff improve their well-being.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06919952

• Wood smoke and nasal immune response to the flu

  This study will test if a short, two-hour wood smoke exposure changes nasal immune responses, symptom severity, and antibody production after a live nasal flu vaccine in healthy adults aged 18 to 49.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06841913

• Transitional care intervention for Alzheimer's patients and their caregivers

  This study tests a new program to help Alzheimer's patients and their caregivers adjust better when moving from nursing homes to home or other care settings.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06840587

• Improving parental support for children with hypospadias

  This study is testing whether giving parents different educational resources about hypospadias can help them feel more knowledgeable and comfortable when talking about their child's condition with a doctor.

  Recruiting at 2 sites University of North Carolina, Chapel Hill · Indianapolis, Indiana and 1 other locations · NCT06832280

• Inclusive physical activity program for adults with intellectual disabilities

  This study is testing a new fitness program for adults with intellectual disabilities to see if it helps them be more active and feel better over 16 weeks.

  Recruiting University of North Carolina, Chapel Hill · Fayetteville, Arkansas and 1 other locations · NCT06740162

• Family-centered weight loss program for Black adults

  This study is testing a weight loss program for Black adults that involves family support to see which family activities help them lose weight best over six months.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06724406

• Improving mental health and HIV care for pregnant women in Malawi

  This study is testing a new support program to see if it can help pregnant women living with HIV in Malawi feel better mentally, engage more with their HIV care, and improve their baby's health.

  Recruiting at 4 sites University of North Carolina, Chapel Hill · Lilongwe and 4 other locations · NCT06702722

• Understanding brain activity during therapy for depression

  This study tests how brain activity changes in people with depression during a therapy session, comparing two different approaches to see which one helps more.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06696001

• Parenting program to improve child stress outcomes

  This study is testing whether a parenting program can help reduce stress in young children and improve their relationships with their caregivers.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, South Carolina · NCT06669624

• Xperience™ versus dilute povidone-iodine to prevent infections after implant-based breast reconstruction

  This trial will test whether Xperience™ surgical irrigation reduces infection and complication rates compared with dilute povidone-iodine in women 18 and older having implant-based breast reconstruction after mastectomy.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06649890

• Using TNX-102 SL to reduce acute stress reactions after motor vehicle collisions

  This study is testing if a new medication can help people who have just been in a car accident feel less stressed and prevent long-term trauma symptoms.

  Recruiting at 9 sites Phase 2 University of North Carolina, Chapel Hill · Birmingham, Alabama and 8 other locations · NCT06636786

• Effects of Hormonal Changes on Depression in Women

  This study is testing if hormone treatments can help women aged 18-45 with depression feel better during their menstrual cycle by looking at how hormonal changes affect their mood.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06610305

• Genetic study on eating disorders

  This study is trying to understand the genetic and environmental causes of eating disorders by gathering information from 20,000 people with different eating disorders and healthy individuals.

  Recruiting at 5 sites University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 4 other locations · NCT06594913

• Teacher-delivered mental health support for K–8 students in North Carolina

  This project tests whether training elementary and middle school teachers in North Carolina to deliver brief mental health support can help K–8 students with depression, anxiety, or behavior problems.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06587230

• Improving HIV prevention for postpartum women in Malawi

  This study tests a new approach to help new mothers in Malawi prevent HIV by combining testing and treatment with their baby's vaccination visits and support from their partners and community.

  Recruiting University of North Carolina, Chapel Hill · Lilongwe · NCT06506188

• A new model to prevent mother-to-child HIV transmission in Malawi

  This study is testing a new community-based approach called the PAC-Man model to see if it can better prevent the spread of HIV from mothers to their babies in Malawi compared to standard care.

  Recruiting at 2 sites University of North Carolina, Chapel Hill · Lilongwe, Central Region and 2 other locations · NCT06493357

• Intervention to help people cope with acute stress reactions

  This study tests a new quick support method called iCOVER to help people dealing with acute stress reactions feel better and get back to normal after a stressful event.

  Recruiting at 4 sites University of North Carolina, Chapel Hill · Belmont, Massachusetts and 4 other locations · NCT06482567

• Evaluating the Alliance180 Program's effects on well-being

  This study is testing if the Alliance180 Program can improve the physical and mental well-being of US Veterans, First Responders, and Front Line Healthcare Workers.

  Recruiting at 2 sites University of North Carolina, Chapel Hill · Saratoga Springs, New York and 1 other locations · NCT06451523

• Behavioral approaches to reduce diabetes distress in adults with type 1 diabetes

  This study tests two different group programs to see if they can help adults with type 1 diabetes feel less stressed about managing their condition.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06405373

• Improving mental health services in Malawi through leadership alignment

  This study is testing if getting leaders on board with a new approach can help improve mental health services in Malawi more effectively than just having champions for the cause.

  Recruiting at 12 sites University of North Carolina, Chapel Hill · Chiradzulu and 11 other locations · NCT06399991

• Using ultrasound to check gastrostomy tube position

  This study is testing if using ultrasound to check the position of gastrostomy tubes in kids is just as good and faster than the usual method called fluoroscopy.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06361498

• Caring Connections: youth suicide detection and support

  This pilot will test whether Caring Connections, a culturally adapted 90-day care coordination program delivered through community and faith-based hubs, helps high-risk Black and other youth aged 13–19 reduce suicidal thoughts and connect with mental health services.

  Recruiting University of North Carolina, Chapel Hill · Charlotte, North Carolina · NCT06353711

• Using 3-D imaging to improve ultrasound treatment for essential tremor

  This study is testing whether using 3-D imaging can make ultrasound treatment for essential tremor more effective for patients who haven't found relief from medication.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06331052

• Using rifaximin to prevent recurrent pouchitis after surgery

  This study is testing if taking rifaximin daily for a year can help prevent pouchitis from coming back in people who have had surgery for ulcerative colitis.

  Recruiting at 2 sites Phase 4 University of North Carolina, Chapel Hill · New York, New York and 1 other locations · NCT06312683

• Effects of beta-blockers on stress-related inflammation and brain responses

  This study tests if the heart medication propranolol can help reduce stress-related inflammation and improve brain responses in people dealing with psychological stress.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06263452

• Teacher-led mental health care for adolescents

  This study is testing a new way for trained teachers to provide mental health support to teenagers in rural schools to see if it helps them with emotional and behavioral challenges.

  Recruiting University of North Carolina, Chapel Hill · Darjeeling, West Bengal · NCT06248203

• Using hypertonic saline to improve mucus clearance in bronchiectasis

  This study is testing if a special salt solution delivered through a nebulizer can help adults with bronchiectasis clear mucus from their lungs better.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06242795

• Training program to improve dementia care in assisted living

  This study is testing two different online training programs for staff in assisted living facilities to see which one helps them provide better care for residents with dementia.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06239688

• Impact of Avocado Consumption on Breastfeeding and Infant Brain Development

  This study is testing if eating five avocados a week can improve the nutrients in breast milk and help babies' brain development during breastfeeding.

  Recruiting University of North Carolina, Chapel Hill · Kannapolis, North Carolina · NCT06208085

• Comparing two types of bupivacaine for pain relief in wrist surgery

  This study is testing whether a new type of bupivacaine can provide better pain relief than the standard version for adults having wrist surgery.

  Recruiting Phase 3 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06179004

• Assessing HIV prevention methods during pregnancy and breastfeeding

  This study is testing whether a long-acting injectable HIV prevention method is safer than a daily pill for pregnant women and their babies in Malawi.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Lilongwe · NCT06158126

• Investigation of Nontuberculous Mycobacteria Outbreaks in Healthcare Settings

  This study is trying to find out if nontuberculous mycobacteria infections in healthcare settings are spreading between patients and where they might be coming from.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06155747

• Improving economic stability and HIV prevention for young adults in Baltimore

  This study is testing whether a program that helps young adults in Baltimore find jobs and learn about HIV prevention can improve their economic stability and health.

  Recruiting University of North Carolina, Chapel Hill · Baltimore, Maryland · NCT06096324

• Non-invasive brain stimulation for motivation issues in Parkinson's Disease

  This study is testing if a type of brain stimulation can help reduce feelings of apathy in people with Parkinson's Disease.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06087926

• Understanding how puberty and testosterone affect adolescent mood

  This study is trying to see how puberty and testosterone affect the moods of boys and girls aged 11 to 14 who have had stress or mild depression.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06072677

• Using 19F MRI to study lung ventilation in children with cystic fibrosis

  This study is testing a new MRI method to see how well children with mild cystic fibrosis breathe compared to healthy kids their age.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06066723

• Effect of Finerenone on Kidney Transplant Recipients

  This study is testing if a new medication called finerenone can help kidney transplant recipients stay healthy and avoid complications related to their kidneys and heart.

  Recruiting Phase 2 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06059664

• Measuring lung function in cystic fibrosis using advanced MRI techniques

  This study is testing a new MRI method to see how well the lungs are working in people with cystic fibrosis over a year, comparing it to standard lung tests.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06057714

• Optimizing weight loss interventions for older adults

  This study is testing which weight loss program works best for older adults with obesity and health issues, comparing a medical approach to a coaching method.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT06044571

• Chromatic Retinal Stimulation to Help With Chronic Pain

  This study tests whether different color light delivered to the retina can reduce pain and pain sensitivity in adults with fibromyalgia or chronic low back pain.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05956067

• Graded exposure and mindfulness meditation for patients recovering from ACL reconstruction

  This study is testing if a combination of mindfulness meditation and graded exposure can help young adults who have had ACL surgery feel less anxious and improve their reaction time during recovery.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05949177

• Using supplements to improve physical function in older adults

  This study is testing whether taking beta-hydroxy-methylbutyrate and vitamin D supplements for 12 weeks can help older adults aged 65 to 85 improve their physical function.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05877846

• Improving walking for people with Parkinson's disease using metronome training

  This study is testing if metronome-guided walking training can help people with Parkinson's disease walk better by encouraging them to take larger and faster steps.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05864157

• Gait rehabilitation using biofeedback for knee injuries

  This study is testing if real-time feedback on walking can help younger people who had knee surgery recover better and avoid early signs of osteoarthritis.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05848622

• Cochlear implants for young children with single-sided deafness

  This study is testing if cochlear implants can help young children with single-sided deafness hear better and develop language skills as they grow.

  Recruiting University of North Carolina, Chapel Hill · Durham, North Carolina · NCT05775367

• Using virtual reality mindfulness meditation to help women recover after ACL surgery

  This study is testing if virtual reality mindfulness meditation can help women recover better after ACL surgery by reducing fear and improving their movement patterns.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05527171

• Reducing maternal health disparities for Black women

  This study is trying different ways to improve prenatal care for Black women in North Carolina to see if it can help reduce low birthweight babies and make their overall experience better.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05484804

• Using therapy dogs to reduce anxiety in pediatric dental visits

  This study is testing if having therapy dogs during dental visits can help reduce anxiety in young children aged 4 to 8.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05464888

• Validation of wearable bioelectronic sensors

  This study tests new wearable sensors to see if they are safe and work well while people do different activities, including exercise.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05397951

• Effects of Estradiol on Depression and Psychosis in Perimenopausal Women

  This study tests if giving estradiol to women aged 44-55 who are going through perimenopause can help improve their depression and psychosis symptoms.

  Recruiting Phase 4 University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT05282277

• Enhancing parent-child relationships in primary care settings

  This study is testing a new program to see if it can help improve relationships between parents and their young children while also reducing child maltreatment.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 1 other locations · NCT05233150

• Effects of Vibration on Knee Health After ACL Surgery

  This study is testing if adding vibration therapy to regular rehab can help people recovering from ACL surgery have better knee health and lower the chance of future injuries.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina and 1 other locations · NCT04875052

• Analyzing speech changes in jaw surgery patients

  This study looks at how jaw surgery affects the way people speak by recording their speech and tongue movements before and after the surgery.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT04117360

• Exploring the effects of whole eggs on infant brain development

  This study is testing whether giving whole egg powder to breastfeeding mothers can help improve their infants' brain development compared to egg white powder.

  Recruiting University of North Carolina, Chapel Hill · Kannapolis, North Carolina · NCT03838536

• Measuring how off-label medications affect children

  This study is testing how off-label medications affect young children by looking at drug levels in their blood and other fluids to better understand their safety and effectiveness.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT01286519

• Understanding the genetic causes of lung disease in Primary Ciliary Dyskinesia

  This study is trying to find out which genes cause lung problems in people with Primary Ciliary Dyskinesia to better understand how it affects breathing and related conditions like asthma and COPD.

  Recruiting University of North Carolina, Chapel Hill · Chapel Hill, North Carolina · NCT00807482

Quick answers

How many clinical trials run by University of North Carolina, Chapel Hill are recruiting right now?

96, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 13 countries. The most sites are in United States (88 trials), Malawi (5 trials), Tanzania (1 trial), India (1 trial), Uganda (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 9, Phase 2: 4, Phase 1: 2, Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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