Effects of Vibration on Knee Health After ACL Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the impact of vibration therapy on post-traumatic knee osteoarthritis risk and secondary ACL injury in individuals recovering from ACL reconstruction surgery. Participants will be randomly assigned to receive standard rehabilitation, standard rehabilitation with whole body vibration (WBV), or local muscle vibration (LMV). The study aims to assess various outcomes including quadriceps muscle function, gait biomechanics, patient-reported outcomes, and MRI indicators of knee joint health. The hypothesis is that vibration therapy will enhance recovery and reduce the risk of complications compared to standard rehabilitation alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 16 to 35 years
* Unilateral, primary ACLR with bone-patellar tendon-bone autograft

Exclusion Criteria:

* History of prior ACL injury or revision ACLR
* History of prior knee surgery
* Requirement of multiple ligament surgery at time of ACLR
* Concomitant injuries or surgical procedures at the time of ACLR that would delay early post-operative weight bearing based on surgeon recommendations (e.g. lower extremity fracture, intra-articular fracture, microfracture procedure)
* Removal of more than 1/3 of the medial or lateral meniscus at the time of ACLR
* Articular cartilage damage greater than 3A on the International Cartilage Repair Society Criteria at the time of ACLR
* History of musculoskeletal injury to either leg in the 3 months prior to participation other than primary ACL injury
* Prior diagnosis of radiographic OA in any joint of the lower extremity
* History of neurological disorder (e.g. stroke, multiple sclerosis, etc.)
* Contraindications for MRI (e.g. extreme claustrophobia, cardiac pacemaker, cochlear implant, metal foreign bodies, aneurism clip, etc.)
* Pregnant or planning to become pregnant

Where it's running

• MOTION Science Institute
  Chapel Hill, North Carolina, United States Recruiting
• Womack Army Medical Center
  Chapel Hill, North Carolina, United States Not yet recruiting

Study contacts

• Principal investigator: Troy Blackburn, PhD — University of North Carolina, Chapel Hill
• Study coordinator: Troy Blackburn, PhD
• Email: troyb@email.unc.edu
• Phone: 919-843-2021

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.