Investigation of Nontuberculous Mycobacteria Outbreaks in Healthcare Settings

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to standardize the investigation of nontuberculous mycobacteria (NTM) outbreaks in healthcare facilities. It will analyze respiratory NTM isolates from patients to determine if they are genetically related, indicating potential patient-to-patient transmission. The study will also assess environmental samples to identify sources of NTM acquisition. Participants will complete a demographic questionnaire to support the epidemiological investigation. The research utilizes whole genome sequencing to identify clusters of infections and adapt CDC guidelines for outbreak investigations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female participant of any age who has a history of NTM or a first positive NTM culture collected as part of routine clinical care from expectorated sputum, induced sputum and/or bronchoalveolar lavage.

Exclusion Criteria:

* No NTM respiratory culture

Where it's running

• University of North Carolina- Chapel Hill
  Chapel Hill, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Jane Gross, MD, PhD — University of North Carolina, Chapel Hill
• Study coordinator: Principal Investigator
• Email: Jane_gross@med.unc.edu
• Phone: 919-445-4240

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.