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Clinical trials and research at McGill University Health Centre/Research Institute of the McGill University Health Centre

• 67Clinical trials
• 2New in 30 days
• 12Countries

Newest trials

All recruiting trials (67)

• Semaglutide on body composition in adults with type 1 diabetes and overweight/obesity

  This study tests whether weekly semaglutide changes body composition in adults with type 1 diabetes who are overweight or obese, compared with a placebo over 24 weeks.

  Recruiting Phase 2/3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07891156

• Adjuvant Hypofractionated Radiotherapy for Endometrial Cancer: Safety, Efficacy, and Quality of Life

  This study tests whether a shorter course of pelvic radiotherapy is safe and effective for women with non-metastatic endometrial cancer, and how it affects their quality of life.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07871838

• Can personality traits influence eye side effects from glaucoma meds?

  This study tests whether personality traits are linked to how often or how severely people experience eye side effects from glaucoma medications.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07739784

• Wireless MicroPremVitals Button Sensor for the NICU

  This study tests a tiny wireless sensor system to monitor heart rate, oxygen, and temperature in extremely preterm babies in the NICU to see if it works safely without wires.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07732257

• Wireless NIRS Sensor Use in the NICU for Monitoring on Neonates

  A wireless NIRS sensor is tested on infants in the NICU to see how well it stays on and how it notes brain signals when used alongside standard wired sensors.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07732244

• People with Osteoporosis: See if Walk-BEST Gait Program Helps You Walk Safer

  This pilot study tests whether older adults with osteoporosis can use the Walk-BEST gait training with a wearable sensor to walk more safely and reduce fall risk.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07621679

• Paced breathing to improve autonomic function after pediatric concussion

  This project tests whether a daily 10-minute paced breathing exercise started within 72 hours of injury can help children and teens (ages 9–18) recover faster and reduce autonomic-related symptoms after concussion.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07572734

• Dexamethasone for post-mastectomy chronic pain

  This trial will test whether giving dexamethasone during mastectomy lessens long-term post-mastectomy chronic pain in adult women.

  Recruiting Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07556952

• Detection of Respiratory Events in Extremely Preterm Infants Using Acoustic Monitoring

  A new acoustic monitoring approach is being tested to detect breathing problems in very preterm babies to help NICU teams spot and manage apnea and related events.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07552025

• Biomarker-guided antibiotic decisions for ICU patients

  This trial will test whether using a biomarker signature to guide antibiotic decisions for ICU patients who recently started antibiotics can reduce unnecessary antibiotic use without causing worse outcomes.

  Recruiting at 4 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 3 other locations · NCT07481773

• Comparing inflammation markers from dried blood spots and standard blood draws

  This will see if finger‑prick dried blood spot samples can measure inflammation markers as accurately as standard venous blood draws in adults receiving a planned vaccine or other scheduled stressor.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07435285

• HMB and 2-HOBA to Support Muscle Strength and Thinking in Adults 65+

  This study tests whether taking HMB, 2-HOBA, or both can improve muscle strength and cognitive function in adults over 65.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07419633

• How infertility and fertility treatments affect women's sexual function and behavior

  This project tries to see if infertility and fertility treatments like IVF change sexual desire, satisfaction, or sexual activity in women under 45 seeking fertility care.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07376109

• Minimal Effective Volume for double-injection costoclavicular block

  This study tests the smallest amount of lidocaine that still provides a successful double-injection costoclavicular nerve block in adults having upper-extremity surgery.

  Recruiting Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07374952

• Vancomycin pulse-and-taper versus 10-day fidaxomicin to prevent recurrent C. difficile

  This trial tests whether a vancomycin pulse-and-taper schedule works as well as a 10-day course of fidaxomicin to prevent recurrence in adults with a first episode or first recurrence of C. difficile.

  Recruiting at 2 sites Phase 3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Edmonton, Alberta and 1 other locations · NCT07328971

• Reducing ustekinumab dosing for Crohn's disease and ulcerative colitis

  This will try giving ustekinumab less often—changing from every 4 or 8 weeks to every 8 or 12 weeks—to see if people with Crohn's disease or ulcerative colitis in deep remission can stay well.

  Recruiting Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07303686

• Tirzepatide added to an automated insulin delivery system to help adults with type 1 diabetes manage blood sugar

  This study tests whether once-weekly tirzepatide can help adults with type 1 diabetes use their insulin pumps more easily, possibly reducing the need to count carbohydrates at meals.

  Recruiting Phase 2/3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 3 other locations · NCT07284511

• Reducing unnecessary medications in older adults with rheumatic conditions

  This project will test whether giving doctors individualized MedSafer reports plus patient EMPOWER brochures helps people 60+ with rheumatic conditions who take five or more regular medications stop or reduce risky medicines.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07278609

• Helping couples communicate better to improve step-count prescriptions for people with type 2 diabetes

  This project will test whether teaching couples better ways to communicate, alongside giving both partners step-count prescriptions, helps people with type 2 diabetes walk more.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 2 other locations · NCT07142512

• Increasing access to needle-and-syringe programs in Canadian federal prisons

  This project will try a package of implementation strategies to increase use of needle-and-syringe programs by people who inject drugs in nine Canadian federal prisons.

  Recruiting at 3 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Edmonton, Alberta and 8 other locations · NCT07122219

• Using bubble CPAP sounds to measure airway pressure in premature infants

  This project will try to see if the sounds made by bubble CPAP can tell us how much airway pressure very premature infants (born before 32 weeks) are actually receiving.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT07060833

• Preserving the rectum in patients with rectal cancer using targeted radiation therapy

  This study is testing if targeted radiation therapy can help patients with rectal cancer avoid surgery while still keeping their cancer under control.

  Recruiting Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06991465

• Preventing C. difficile recurrence with short-course oral vancomycin during later antibiotics

  This trial tests whether taking short-course oral vancomycin while you need systemic antibiotics can prevent a recurrence of C. difficile in adults recently treated for CDI.

  Recruiting Phase 2/3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06979609

• Canagliflozin to improve ultrafiltration and reduce peritoneal fibrosis in people on peritoneal dialysis

  We will test whether taking canagliflozin reduces glucose absorption by the peritoneal membrane and improves ultrafiltration in people on peritoneal dialysis.

  Recruiting Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06913647

• Evaluating the effects of Semaglutide and Empagliflozin with Automated Insulin Delivery on diabetes control in adults with Type 1 Diabetes

  This study is testing if adding two diabetes medications, Semaglutide and Empagliflozin, to automated insulin delivery systems can help adults with Type 1 Diabetes better manage their blood sugar levels.

  Recruiting Phase 3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06894784

• Using wearable devices and AI to predict COPD flare-ups

  This study is testing if wearable devices and daily symptom reports can help predict flare-ups in people with COPD using artificial intelligence.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06802003

• Monitoring vital signs of newborns using advanced wireless sensors

  This study is testing a new wireless sensor to see if it can safely and accurately monitor the vital signs of healthy newborns during their first two hours after birth compared to the traditional wired system.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Londrina, Paraná and 4 other locations · NCT06693817

• Switching to dabigatran versus staying on apixaban/edoxaban/rivaroxaban for S. aureus bloodstream infection

  This trial will try whether switching people with S. aureus bloodstream infection who are already taking apixaban, edoxaban, or rivaroxaban to dabigatran leads to better outcomes.

  Recruiting at 3 sites Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · St. John's, Newfoundland and Labrador and 2 other locations · NCT06650501

• Clopidogrel versus aspirin to lower cardiovascular and infection complications in people with Staphylococcus aureus bloodstream infection

  This will try switching people with Staphylococcus aureus bloodstream infection who are already taking aspirin for heart protection to clopidogrel to see if it improves infection outcomes.

  Recruiting at 3 sites Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · St. John's, Newfoundland and Labrador and 2 other locations · NCT06650488

• Comparing Daptomycin and Vancomycin for MRSA Bloodstream Infections

  This study is testing whether daptomycin or vancomycin works better for treating bloodstream infections caused by MRSA in patients.

  Recruiting at 20 sites Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · Blacktown, New South Wales and 19 other locations · NCT06637332

• Social prescribing to help women with heart failure stick to treatments and avoid hospital visits.

  This project will try social prescribing—connecting women with heart failure to community supports—to help them take heart medicines and reduce hospitalizations.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT06628973

• Using intravenous acetaminophen to prevent delirium after heart surgery

  This study is testing if giving acetaminophen through an IV can help prevent delirium in adults after heart surgery compared to taking it by mouth.

  Recruiting at 4 sites Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · Vancouver, British Columbia and 7 other locations · NCT06613178

• Evaluating COVID-19 and influenza vaccine schedules for immunocompromised individuals

  This study is testing different ways to give COVID-19 and flu vaccines to people with weakened immune systems to see which method works best for their protection.

  Recruiting at 2 sites Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 2 other locations · NCT06599658

• Non-opioid pain management after breast surgery

  This study is testing whether non-opioid pain relief can help people recovering from breast surgery feel better and heal without using traditional opioid medications.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06507345

• Shorter, Safer Preventive Treatment for Latent TB

  This trial will test whether shorter preventive treatments—higher‑dose rifampin for two months or one‑month rifapentine combinations—are as safe and easier to finish as the current four‑month rifampin regimen for people with latent tuberculosis.

  Recruiting at 13 sites Phase 2/3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Cotonou and 13 other locations · NCT06498414

• Try the elleFA app to help track endometriosis symptoms and treatments.

  This project will try a smartphone app called elleFA to help pre-menopausal women with known or suspected endometriosis who are receiving care at the McGill University Health Centre track symptoms and treatments more accurately.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06452407

• Home-based exergaming for children with spinal muscular atrophy

  This study is testing if playing a fun video game at home can help kids and teens with spinal muscular atrophy feel happier and more engaged in their daily activities.

  Recruiting at 5 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Calgary, Alberta and 4 other locations · NCT06396325

• Using a closed-loop system with semaglutide to simplify diabetes management

  This study is testing if weekly injections of semaglutide can help people with type 1 diabetes manage their blood sugar better without having to count carbs, compared to a placebo.

  Recruiting Phase 2/3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06387199

• Improving healthcare for migrant families with children who have special needs

  This study is testing whether a patient navigator program can help migrant families with children who have special healthcare needs get better support compared to regular care.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Toronto, Ontario and 2 other locations · NCT06373588

• Investigating new methods for oral immunotherapy in food allergies

  This study is testing new ways to use oral immunotherapy to help people with food allergies, like those to peanuts and milk, feel safer and have fewer allergic reactions during treatment.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06256146

• Observational study on retinal degeneration in Zellweger Spectrum Disorder

  This study is trying to understand how vision loss happens in people with Zellweger Spectrum Disorder by checking their eyesight and health every year.

  Recruiting at 3 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Rochester, New York and 2 other locations · NCT06190626

• Canagliflozin for heart health in patients with advanced kidney disease

  This study is testing if a diabetes medication called canagliflozin can improve heart health in people with advanced kidney disease and those on dialysis.

  Recruiting Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06182839

• Liver and spleen stiffness testing to diagnose clinically significant portal hypertension

  This project tests whether liver and spleen stiffness measurements can predict portal-hypertension complications in adults with advanced chronic liver disease.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06181409

• Using high-dose insulin therapy to enhance liver function before surgery

  This study is testing if high-dose insulin therapy can help improve liver function in patients who are about to have major liver surgery.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT06126419

• Using sildenafil to treat brain injury in newborns after asphyxia

  This study is testing if sildenafil can help newborns with brain injuries from lack of oxygen at birth recover better after treatment with cooling therapy.

  Recruiting at 3 sites Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Denver, Colorado and 2 other locations · NCT06098833

• Virtual home-based exercise program for kidney transplant candidates

  This study is testing a 12-week online exercise and education program for people waiting for a kidney transplant to see if it helps them get stronger before surgery.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT06089473

• Monitoring clinical stability in extremely low birth weight infants after extubation

  This study is trying out a new monitoring system to see if it can help doctors better track the health of extremely low birth weight infants after they are taken off breathing machines.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT06037083

• Preventing gastric outlet obstruction in patients with advanced periampullary cancer

  This study is testing if a new procedure called ProEUS-GE can help prevent stomach blockages in people with advanced periampullary cancer compared to just using ERCP alone.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal and 4 other locations · NCT05994521

• Biobank for studying genetic factors in aortic stenosis and cardiovascular diseases

  This study is collecting samples and health information from people with aortic stenosis and other heart diseases to see if they can find new genetic clues that could improve diagnosis and treatment.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT05930899

• Using Estetrol and Drospirenone to Shrink Ovarian Endometriomas

  This study is testing if a hormonal treatment called Estetrol and Drospirenone can help shrink painful ovarian cysts in women with endometriosis and improve their chances of getting pregnant.

  Recruiting Phase 4 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT05837624

• MARVIN Chatbots for Health Information

  This study is testing a new chatbot designed to provide helpful health information for people with different health conditions, like breast cancer and pediatric emergencies, to see how well it works for them.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT05789901

• Comparing left bundle branch pacing to standard right ventricular pacing

  This study tests if a new way of pacing the heart called left bundle branch pacing can help people with a serious heart condition live longer and feel better compared to the standard pacing method.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT05015660

• Combining two antibiotics to treat Staphylococcus aureus bacteremia

  This study is testing if using two antibiotics together can help adults with Staphylococcus aureus bacteremia get better faster than the usual treatment.

  Recruiting at 8 sites Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Calgary, Alberta and 7 other locations · NCT04886284

• Low-dose trimethoprim-sulfamethoxazole treatment for Pneumocystis (PCP) pneumonia

  This trial will test whether a lower daily dose of TMP‑SMX works as well but causes fewer side effects than the standard dose in adults with Pneumocystis (PCP) pneumonia who are immunocompromised.

  Recruiting Phase 3 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04851015

• Treatment for Mitochondrial Depletion Syndrome in Children

  This study is testing if a new treatment can help children with Mitochondrial Depletion Syndrome feel better and improve their brain function.

  Recruiting Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04802707

• Predicting preeclampsia early using arterial stiffness in high-risk pregnancies

  This study is testing a new way to spot early signs of preeclampsia in high-risk pregnancies by measuring how stiff blood vessels are, along with other tests, to help improve care for moms and babies.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04783597

• Effects of Dexamethasone on Heart Function in Extremely Preterm Infants

  This study looks at how the medication dexamethasone affects heart function and lung fluid in extremely preterm infants born before 29 weeks to see if it helps improve their health.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04644094

• A quick 10-minute heart scan for cardiac diseases

  This study is testing a quick 10-minute heart scan to see if it can help diagnose heart problems better and faster for many patients without needing special dyes.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04464655

• Hypofractionated radiation therapy and hormone treatment for prostate cancer after surgery

  This study is testing if a new type of radiation therapy combined with hormone treatment can help men with high-risk prostate cancer feel better and reduce the chances of their cancer coming back after surgery.

  Recruiting at 2 sites Phase 2 McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT04249154

• Observational study on congenital diaphragmatic hernia in newborns and children

  This study looks at how congenital diaphragmatic hernia affects the heart and lungs in newborns and children to see if they face ongoing health challenges as they grow up.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04114578

• Examining heart and lung health in extremely premature infants

  This study looks at the heart and lung health of extremely premature babies to see if they have problems that could affect their future health and development.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04114435

• Monitoring oxygen levels in newborns with congenital heart defects

  This study is testing a new way to monitor oxygen levels in newborns with congenital heart defects to see how it can help doctors understand their heart and blood flow better.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04106479

• Single fraction radiation therapy for prostate cancer

  This study is testing if a single dose of a special type of radiation therapy, combined with a gel to protect nearby organs, can safely treat men with low to moderate-risk prostate cancer.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT04004312

• Identifying Monogenic Diabetes Misdiagnosed as Type 1

  This study is trying to find out how often young people are wrongly diagnosed with type 1 diabetes when they actually have a rare form called monogenic diabetes, by testing their blood and looking for specific genetic changes.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT03988764

• A wait-and-see approach for rectal cancer patients after treatment

  This study is testing whether some rectal cancer patients who respond well to treatment can safely skip surgery and just be closely monitored instead.

  Recruiting at 2 sites McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec and 1 other locations · NCT03001362

• Registry for Familial Hypercholesterolemia in Canada

  This study is setting up a registry for people with familial hypercholesterolemia in Canada to help doctors manage their care and support research on this genetic condition.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT02009345

• Observational study of patients with peroxisome biogenesis disorders

  This study is looking to learn more about Peroxisome Biogenesis Disorders by collecting health information from patients to help improve future treatments.

  Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre · Montreal, Quebec · NCT01668186

Quick answers

How many clinical trials run by McGill University Health Centre/Research Institute of the McGill University Health Centre are recruiting right now?

67, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 12 countries. The most sites are in Canada (67 trials), Brazil (2 trials), Switzerland (2 trials), United States (2 trials), Benin (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 8, Phase 2: 8, Phase 2/3: 5, Phase 3: 3. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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