Clinical trial Recruiting at 1 site Observational Ages 18 and up

Can personality traits influence eye side effects from glaucoma meds?

Official title: Personality Traits and Their Relation to Ocular Adverse Effects From Glaucoma Medications

Run by McGill University Health Centre/Research Institute of the McGill University Health Centre · NCT07739784 · Data updated 2026-11-12

This study tests whether personality traits are linked to how often or how severely people experience eye side effects from glaucoma medications.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment352 (estimated)
SponsorMcGill University Health Centre/Research Institute of the McGill University Health Centre
Academic / other
Locations1 site (Montreal, Quebec)
StatusRecruiting
StartedFebruary 25, 2026
Main results expectedJuly 1, 2027
Study endsAugust 1, 2027
Registry record updatedJuly 31, 2026
Trial IDNCT07739784 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18 and older with glaucoma who are currently or previously treated with glaucoma medications and able to complete surveys in English or French.

Probably not a fit

Patients without glaucoma medication exposure or those unable to complete questionnaires may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will enroll adults using or who have used glaucoma medications to see if personality traits relate to ocular adverse effects. Participants complete a questionnaire measuring five personality traits and provide basic demographics, while researchers review medical records for glaucoma medications and side effects. The study focuses on whether certain traits are associated with the occurrence or severity of side effects and if personality influences reporting or management of these events. No interventions are involved; data will be analyzed to identify potential associations.

Why it matters

Potential benefit: If a link is found, clinicians could tailor counseling and monitoring to individual personality profiles to improve tolerance and adherence.

How similar studies have gone: To date, there is limited evidence on personality and ocular medication side effects, making this area exploratory.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18 years or older.
* Diagnosis of glaucoma.
* Current or previous treatment with one or more glaucoma medications.
* Able to provide informed consent.
* Able to complete the study questionnaires in English or French.

Exclusion Criteria:

* Uncontrolled anxiety or depression that was present before glaucoma medication treatment began.
* Unable to provide informed consent.
* Unable to complete the study questionnaires in English or French.

Where it's running

  • McGill University Health Center
    Montreal, Quebec, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.