Examining heart and lung health in extremely premature infants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the cardiac performance and pulmonary vascular disease in infants born at less than 29 weeks of gestation. The researchers hypothesize that these premature infants experience compromised heart function and elevated pulmonary pressures, which may lead to increased morbidity and poorer neurodevelopmental outcomes. The study employs novel echocardiography techniques to detect cardiac anomalies that traditional imaging may miss, with the goal of identifying infants at risk for later pulmonary hypertension. The findings could provide insights into the long-term health of these vulnerable infants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Infants born at \<29 weeks' gestational age admitted to the NICU
* All infants born at \<29 weeks' gestational age followed at MCH clinic after an admission in the NICU for prematurity \<29 weeks

Exclusion Criteria:

* Congenital heart disease (except an atrial (ASD) or ventricular septal defect (VSD), or a patent ductus arteriosus (PDA))
* Congenital severe lung or airway malformation (choanal atresia, trachea-esophageal fistula or congenital pulmonary airway malformation)
* Genetic disorder (Trisomy 21).

Where it's running

• Mcgill University Health Centre
  Montreal, Quebec, Canada Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.