A quick 10-minute heart scan for cardiac diseases
A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease
This study is testing a quick 10-minute heart scan to see if it can help diagnose heart problems better and faster for many patients without needing special dyes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2130 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | McGill University Health Centre/Research Institute of the McGill University Health Centre Academic / other |
| Locations | 1 site (Montreal, Quebec) |
| Trial ID | NCT04464655 on ClinicalTrials.gov |
What this trial studies
This study focuses on developing a new 10-minute cardiovascular magnetic resonance (CMR) protocol aimed at improving diagnostic capabilities for various cardiac conditions without the need for contrast agents. The protocol is designed to standardize assessments for approximately 70% of cardiac patients by evaluating heart function and myocardial tissue characteristics. The study will assess the clinical feasibility, performance, and cost-effectiveness of this approach across different populations, including those with non-ischemic cardiomyopathies and ischemic heart disease.
Who should consider this trial
Good fit: Ideal candidates include adults over 18 years old who require a clinically indicated CMR exam and do not have significant medical conditions affecting their cardiovascular or respiratory systems.
Not a fit: Patients with MRI contraindications, such as those with pacemakers or other incompatible devices, will not benefit from this study.
Why it matters
Potential benefit: If successful, this protocol could lead to faster and more accurate diagnoses for patients with cardiac diseases, potentially improving treatment outcomes.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in improving CMR protocols, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Healthy Volunteers Inclusion Criteria: * Age: \> 18y, Informed consent No known current or pre-existing significant medical conditions that would affect the cardiovascular or respiratory system Exclusion Criteria: * General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam.Regular nicotine consumption during the last 6 months Patients Inclusion Criteria: * Age: \>18 y, Informed consent, Clinically indicated CMR exam Exclusion Criteria: * General MRI contraindications: MR- incompatible devices such as pacemakers, defibrillators, or implanted material or foreign bodies Vasoactive medication (e.g. nitro) during the 12 hours prior to the exam. Consumption of caffeinated drinks or foods (including cocoa and chocolate) during the 12 hours prior to the exam. Regular nicotine consumption during the last 6 months
Where this trial is running
Montreal, Quebec
- McGill University Health Center — Montreal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: Matthias G Friedrich, MD — Research Institute of the McGill University Health Center
- Study coordinator: Elizabeth Konidis
- Email: elisavet.konidis@muhc.mcgill.ca
- Phone: 514-934-1934
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.