Sponsor or institution
Clinical trials and research at Magee-Women's Res Inst and Foundation
As of November 12, 2026, Find a Trial lists 49 NIH-funded research projects at this institution, with $27.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 49NIH research projects
NIH-funded research (newest 40 of 49)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Week-long bioadhesive vaginal film that slowly releases antibodies to prevent pregnancy and STIs
Creating a vaginal film that slowly releases antibodies for up to seven days to help women prevent pregnancy and infections like HIV and HSV.
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Reducing post-delivery blood pressure gaps for Black women after pregnancy
A large 2-arm study tests a postpartum blood pressure program to close racial gaps in high blood pressure after delivery, focusing on Black women with hypertensive disorders of pregnancy.
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Molecular clues to imprinting problems after fertility treatments
This project looks for molecular clues that explain why fertility treatments can sometimes lead to imprinting problems in babies.
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Pregnancy and newborn health at Magee-Womens Hospital
This program invites pregnant people to join research at Magee-Womens Hospital starting in early pregnancy to test ways to prevent preterm birth and improve maternal and newborn health.
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Preeclampsia's link to small blood vessel changes in the midlife brain
This project looks at whether women who had preeclampsia during pregnancy show early small-vessel changes in the brain and related thinking differences in midlife.
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Gene and cell therapy approaches for severe male infertility (nonobstructive azoospermia)
This project is developing gene-editing and cell-based therapies to try to restore sperm production in men with severe nonobstructive azoospermia.
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Growing egg and sperm-like cells in the lab to find causes of infertility
This project grows egg- and sperm-like cells from stem cells to find genetic and epigenetic reasons some people cannot make healthy gametes.
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Improving genetic diagnosis for male infertility
This project uses whole-genome sequencing and new analysis methods to find genetic causes of unexplained male infertility so more men can get clear diagnoses.
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Genetic causes of male infertility and azoospermia
This project aims to find gene changes that cause nonobstructive azoospermia in men to improve diagnosis and guide future treatments.
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Repairing injuries to the pubovisceral muscle after childbirth
This study is looking at how injuries to a specific muscle during vaginal childbirth can lead to pelvic organ prolapse later on, and it aims to create a new healing method to help women recover better than with standard surgery.
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Finding early signs of preterm birth and related pregnancy complications
This research aims to create a new blood test for expectant mothers to help identify risks for preterm birth and other pregnancy issues like preeclampsia and poor fetal growth.
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Developing new contraceptive methods for women, especially those who are obese.
This study is working on new birth control methods that are safe and effective, especially for women who are obese, to help prevent unintended pregnancies while keeping health risks low.
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Understanding Mesh Complications in Pelvic Organ Prolapse Repair
This research explores how the design and placement of surgical mesh contribute to complications like pain and mesh exposure in women who have had pelvic organ prolapse surgery.
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Growing human testis tissue in the lab to produce sperm
Researchers are building lab systems to grow immature testis tissue into sperm so boys and men who couldn't bank sperm before cancer treatment might have biological children later.
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Understanding how hyaluronan affects ovarian health and aging
This study looks at how a natural substance in the body called hyaluronan affects the health of ovaries as women get older, focusing on how it impacts fertility and the overall environment of the ovaries.
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Family Check-Up program to improve heart health for new mothers and their young children
A home-visiting program called FCU-Heart that aims to help postpartum mothers with cardiovascular risks and their children up to age three adopt heart-healthy habits.
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Investigating how Egfl6 affects immune responses in uterine cancer
This study is looking at a protein called Egfl6 to see how it affects the immune system's response to a type of endometrial cancer called uterine serous carcinoma, with the hope that understanding this could help develop better treatments for patients.
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How genes are turned on or off in early development
This research aims to understand how genes from parents are controlled during the earliest stages of development, which is important for fertility treatments and certain birth conditions.
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Understanding Ovarian Cancer Cells That Resist Chemotherapy
This project aims to discover new ways to treat ovarian cancer by understanding why some cancer cells survive chemotherapy.
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Investigating how Egfl6 affects immune responses in ovarian cancer
This study is looking at how a growth factor called Egfl6 affects certain immune cells in ovarian cancer, with the goal of finding new ways to boost the body's natural defenses against the disease and improve treatments.
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Helping women with substance use disorders make better contraceptive choices after childbirth
This study is looking to help new moms with substance use disorders make better choices about birth control after having a baby by testing a helpful tool called MyPath, which aims to reduce unexpected pregnancies and support women in using effective contraceptive methods.
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Creating a vaginal film that releases antibodies for contraception and protection against STDs.
This study is testing a new, easy-to-use vaginal film that can help prevent pregnancy and protect against certain viruses, making it a great option for women who want extra safety in their sexual health.
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Understanding how assisted reproduction technologies may cause genetic errors in embryos
This study is looking into how assisted reproductive technologies might affect the DNA of embryos, which could lead to genetic issues in babies, and it aims to find ways to improve these technologies for better health outcomes in future pregnancies.
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Gene therapy to restore fertility in males with Sertoli cell dysfunction
This study is looking at a new gene therapy using a virus to help treat male infertility caused by problems with Sertoli cells, specifically for men who have a condition called non-obstructive azoospermia, and it aims to find a safe and effective way to restore sperm production.
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Transplanting and growing sperm-producing cells for boys who have cancer
This study is looking at ways to help boys who have had cancer treatment and might have trouble having kids later on by testing safe methods to use their own stored testicular tissue or stem cells to restore their fertility.
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Improving coordination and communication in reproductive health research
This study is all about improving teamwork and support for research on reproductive health, which could lead to better treatments and outcomes for people facing fertility challenges.
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Gene therapy for male infertility
This study is looking at new ways to help men with infertility caused by a condition called nonobstructive azoospermia (NOA) by using gene therapy techniques, which could eventually lead to better treatments for couples trying to have a baby.
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Identifying genetic causes of infertility using advanced cell models
This study is exploring new ways to understand infertility by creating lab models that mimic how reproductive cells develop, helping to find hidden genetic factors that might be causing problems for people trying to conceive.
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Improving genetic diagnosis for male infertility
This study is looking to help men who are having trouble with infertility by using advanced genetic testing to find more hidden causes, which could lead to better diagnoses and treatment options.
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Improving understanding of reproductive health and infertility in underserved communities
This study is all about teaching middle and high school students, as well as community college students, about reproductive health and infertility through fun hands-on experiments, especially in low-income areas, so they can learn important skills for their future careers.
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Understanding the genetics behind male infertility
This study is looking at the genes that might cause male infertility, especially a condition called nonobstructive azoospermia, which affects about 1 in 100 men, to help create better tests and treatments for couples dealing with infertility.
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Improving care for pregnant individuals with opioid use disorder in underserved areas
This study is looking at how teamwork among healthcare and support services can help pregnant and new parents dealing with opioid use disorder, especially in areas where resources are limited, to make sure they get the care they need for a healthier pregnancy and parenting experience.
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The link between preeclampsia and cognitive decline in midlife women
This study is looking at how having preeclampsia during pregnancy might affect brain health and memory in women as they get older, to help find early signs of dementia risk.
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Developing systems to mimic human testis development
This study is exploring new ways to grow human testes and produce sperm outside the body to help people who might struggle with infertility after cancer treatments or gender-affirming procedures, using special tissues from their testicles.
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Improving heart health for mothers and young children through home visits
This study is testing a special program called FCU-Heart to help new moms and their kids stay healthy by offering personalized support on things like eating well, exercising, and managing stress, so they can improve their heart health together.
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Investigating substance abuse disorders during pregnancy and childhood
This study is all about helping pregnant people, new moms, and their kids who are dealing with substance use issues by training a diverse group of healthcare professionals to provide better support and care for these families.
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Training future researchers to tackle emerging diseases and health disparities
This study is all about helping new scientists, especially those from under-represented backgrounds, learn how to tackle health issues like those highlighted by COVID-19, so they can make a real difference in fighting diseases and improving health for everyone.
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Understanding how mechanical stresses affect tissue healing after mesh implantation
This study is looking at how different types of mesh used in surgeries for pelvic organ prolapse can affect healing and complications, with the goal of finding the best options to help women recover more comfortably and successfully.
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Understanding how dormant ovarian cancer cells resist treatment
This study is looking at why some ovarian cancer cells can stay inactive and resist standard treatments, with the hope of finding new ways to help patients whose cancer comes back after treatment.
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Understanding how certain genes are regulated during early development
This study is looking at how certain genes are turned on or off depending on whether they come from your mom or dad, especially in very early embryos, to help improve fertility treatments and understand related health issues.
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