Creating a vaginal film that releases antibodies for contraception and protection against STDs.
Official title: Development of a bioadhesive vaginal film for extended release of MPT antibodies
Funded at Magee-Women's Res Inst and Foundation · NIH-11063636 · Data updated 2026-11-12
This study is testing a new, easy-to-use vaginal film that can help prevent pregnancy and protect against certain viruses, making it a great option for women who want extra safety in their sexual health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Magee-Women's Res Inst and Foundation NIH-funded |
| Lab location | 1 site (Pittsburgh, UNITED STATES) |
| Project start | February 1, 2025 |
| Project end | January 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $518,754 |
| NIH project number | 1R61HD117426-01 |
| Project ID | NIH-11063636 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women at high risk for HIV, HSV, and unintended pregnancies.
✕Less likely to help
Patients who are not at risk for HIV, HSV, or unintended pregnancies may not benefit from this research.
What this research studies
This research aims to develop a bioadhesive vaginal film that releases contraceptive and antiviral antibodies over a week after a single application. The film combines a monoclonal antibody for contraception with antibodies targeting HIV and HSV, providing a dual protective effect. It is designed to be discreet, low-cost, and convenient for women at high risk of unintended pregnancy and sexually transmitted infections. Previous studies have shown that similar films are safe and effective, paving the way for this innovative approach.
Why it matters
Potential benefit: If successful, this research could provide women with a new method of contraception and protection against sexually transmitted infections, enhancing their reproductive health options.
How similar studies have gone: Previous studies have demonstrated the safety and efficacy of similar vaginal films, indicating a promising approach for this novel treatment.
Where this research is happening
-
Magee-Women's Res Inst and Foundation
Pittsburgh, United States Active
Researchers
- Principal investigator: Rohan, Lisa Cencia — Magee-Women's Res Inst and Foundation
- Study coordinator: Rohan, Lisa Cencia
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.