Improving genetic diagnosis for male infertility
Project I
This study is looking to help men who are having trouble with infertility by using advanced genetic testing to find more hidden causes, which could lead to better diagnoses and treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Magee-Women's Res Inst and Foundation NIH-funded |
| Lab location | 1 site (Pittsburgh, UNITED STATES) |
| Project ID | NIH-10992991 on NIH RePORTER |
What this research studies
This research focuses on enhancing the understanding and diagnosis of genetic causes of male infertility. By transitioning from whole-exome sequencing to whole genome sequencing, the project aims to identify more genetic variants that contribute to infertility. The researchers will analyze a large database of genetic data to uncover previously overlooked genetic factors and improve diagnostic accuracy. This approach could lead to better clinical outcomes for men struggling with infertility.
Who could benefit from this research
Good fit: Ideal candidates for this research are men over 21 years old who are experiencing unexplained infertility.
Not a fit: Patients who do not have male infertility or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide more accurate diagnoses for men with infertility, leading to targeted treatments and improved chances of conception.
How similar studies have performed: Other research has shown success in identifying genetic causes of infertility using similar genomic approaches, indicating a promising avenue for this project.
Where this research is happening
Pittsburgh, UNITED STATES
- Magee-Women's Res Inst and Foundation — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Conrad, Donald F. — Magee-Women's Res Inst and Foundation
- Study coordinator: Conrad, Donald F.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.