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Clinical trials and research at Maastricht University Medical Center

• 53Clinical trials
• 14Countries

Newest trials

All recruiting trials (53)

• Magnetic Brain Stimulation for Pain in Small Fiber Neuropathy

  This study tests whether repetitive transcranial magnetic stimulation (rTMS) can lessen pain in adults with idiopathic small fiber neuropathy.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07805057

• DRAGON: International registry for patients who had combined portal and hepatic vein embolization before liver surgery

  This registry collects data on patients who had PVE/HVE before liver resection to see if it helps liver regeneration and what factors relate to outcomes.

  Recruiting at 30 sites Maastricht University Medical Center · Chicago, Illinois and 30 other locations · NCT07717437

• Probiotic mix to see if it boosts fullness in adults who are overweight or have obesity

  A probiotic supplement is being tested in adults aged 20-70 who are overweight or have obesity to see if it makes them feel fuller and changes gut bacteria harder after 16 weeks, compared with a placebo.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07715955

• Wearable data to spot IBD flareups in people with ulcerative colitis or Crohn's disease

  This study tests whether heart‑rate variability from participants’ own wearables can help predict IBD flares.

  Recruiting at 2 sites Maastricht University Medical Center · 's-Hertogenbosch and 2 other locations · NCT07647640

• Autologous Fat Grafting vs DIEP flap for reconstructed breast after radiation

  This study tests whether autologous fat transfer can provide similar satisfaction and safety to the DIEP flap procedure for women needing breast reconstruction after mastectomy and radiation.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07641985

• Using IMPROVE to guide carotid revascularisation decisions

  This trial tests whether using the IMPROVE MRI-based score to select patients for carotid revascularisation is as good as standard care based mainly on stenosis degree, among people who have had a recent stroke or TIA due to carotid disease.

  Recruiting Maastricht University Medical Center · Arnhem, Gelderland and 9 other locations · NCT07556887

• Whole-food beef protein and amino acid oxidation in young adults

  This test will see how three dinner doses of minced beef affect 24-hour amino acid oxidation in healthy 18–35-year-olds.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07547176

• Real-world use of LC-OCT to help diagnose basal cell carcinoma

  This study tests how well LC-OCT works in everyday dermatology practice to help diagnose basal cell carcinoma without always needing a biopsy.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07501780

• Boosting Osimertinib brain penetration with febuxostat in EGFR-mutated NSCLC

  This study tests whether adding febuxostat to osimertinib can increase osimertinib levels in the brain for patients with EGFR-mutated NSCLC who do not have CNS metastases.

  Recruiting Phase 2 Maastricht University Medical Center · Amsterdam and 1 other locations · NCT07485452

• Unexplained bleeding disorders in the Netherlands

  This project will try to find blood-based and genetic reasons for unexplained bleeding in people referred to hemostasis centers in the Netherlands.

  Recruiting Maastricht University Medical Center · Nijmegen, Gelderland and 7 other locations · NCT07454161

• Long-term walnut intake and brain function in abdominally obese adults

  This trial tests whether eating walnuts for 24 weeks improves brain blood flow and insulin sensitivity, and whether it boosts thinking and appetite control in adults with abdominal obesity.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07422220

• Tarlatamab for Small Cell Lung Cancer with Brain Metastases

  This phase II study tests whether tarlatamab can help adults with small cell lung cancer that has spread to the brain, by treating both systemic disease and brain tumors.

  Recruiting at 3 sites Phase 2 Maastricht University Medical Center · Amsterdam and 3 other locations · NCT07402343

• 4-week nightly ketogenic supplement to improve nighttime metabolism and muscle health

  We will test whether taking a ketogenic nutritional supplement each evening for 4 weeks helps older adults who are overweight improve their daily energy metabolism patterns and muscle health.

  Recruiting Maastricht University Medical Center · Maastricht · NCT07395973

• Measure total energy use in ICU patients with a doubly labeled water test.

  This will test whether the doubly labeled water method can accurately measure daily calorie needs in adults who are critically ill in the ICU.

  Recruiting Maastricht University Medical Center · Hasselt, Limburg · NCT07256340

• Wild blueberry intake and brain function in older adults

  This trial will test whether regular wild blueberry powder taken over a longer period improves brain blood flow, brain insulin sensitivity, and thinking skills in overweight adults aged 60–75.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07177781

• Plant versus animal protein supplements to improve brain blood flow, insulin response, thinking, and appetite in older adults

  This tests whether two weeks of a daily plant or animal protein supplement can improve brain blood flow, brain insulin response, thinking, and appetite control in overweight or obese adults aged 60–75.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07057245

• Beef-based versus plant-based protein diet for building muscle in older adults

  This test will see if a diet using beef as the main protein or a plant-based diet better boosts muscle protein building in healthy adults aged 65 to 85.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT07049224

• Precision nutrition to prevent diabetes and other metabolic diseases

  This trial will try personalized diets based on each person's metabolic 'metabotype' to see if they improve blood sugar control and prevent type 2 diabetes in adults with overweight or obesity.

  Recruiting at 2 sites Maastricht University Medical Center · Maastricht and 1 other locations · NCT06923644

• Lifestyle intervention for older adults at risk of dementia

  This study is testing a personalized lifestyle program to see if it can help older adults at risk of dementia improve their brain health over a year.

  Recruiting Maastricht University Medical Center · Amsterdam and 1 other locations · NCT06832761

• Investigating left ventricle unloading during extracorporeal life support

  This study looks at how different methods of relieving pressure on the heart can help patients on a special life support system called VA ECLS, especially those in serious heart trouble.

  Recruiting Maastricht University Medical Center · Maastricht · NCT06766006

• Effects of ketone supplements on exercise metabolism

  This study is testing if taking a ketone supplement before and during exercise helps endurance-trained adults use carbohydrates more effectively while they work out.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT06746805

• Higher versus standard protein by feeding tube to boost muscle protein synthesis in ICU patients

  This will test whether giving ventilated, critically ill adults more protein through a feeding tube (about 1.3 g/kg/day) helps their muscles make more protein over four days than standard protein (about 0.8 g/kg/day).

  Recruiting Maastricht University Medical Center · Hasselt, Limburg · NCT06714240

• Effects of Walking Breaks on Cognitive Function and Glucose Metabolism

  This study is testing if taking walking breaks during long periods of sitting can help young adults think better and improve their blood sugar levels.

  Recruiting Maastricht University Medical Center · Maastricht · NCT06700187

• Exploring the role of non-essential amino acids in muscle protein synthesis in healthy young men

  This study is testing whether taking non-essential amino acid supplements can help healthy young men build muscle and improve their metabolism compared to essential amino acids and a control supplement.

  Recruiting Maastricht University Medical Center · Maastricht · NCT06687343

• Observing mechanical complications after heart attacks

  This study is testing different treatment options for patients who have serious heart problems after a heart attack to see which ones work best.

  Recruiting Maastricht University Medical Center · Varese · NCT06676345

• Using fMRI neurofeedback to help manage Parkinson's disease

  This study is testing whether using brain training with fMRI can help people with Parkinson's disease improve their movement and manage their symptoms better.

  Recruiting Maastricht University Medical Center · Cologne and 1 other locations · NCT06582355

• Exercise versus calorie restriction: effects on tumor and muscle protein synthesis in prostate cancer

  This study will test whether daily exercise or cutting calories better changes tumor and muscle protein synthesis in men with early-stage prostate cancer who are scheduled for prostatectomy.

  Recruiting Maastricht University Medical Center · Hasselt · NCT06406803

• Combining sacituzumab govitecan and bevacizumab for treating brain metastases in lung cancer

  This study is testing if a combination of two drugs, sacituzumab govitecan and bevacizumab, can help shrink brain tumors in patients with lung cancer who haven't responded to other treatments.

  Recruiting at 3 sites Phase 2 Maastricht University Medical Center · Amsterdam and 2 other locations · NCT06401824

• Comparing G-POEM and PEG-J treatments for gastroparesis

  This study is testing whether a new procedure called G-POEM or a feeding tube method called PEG-J can help people with stubborn gastroparesis feel better.

  Recruiting Maastricht University Medical Center · Maastricht, Zuid-Limburg · NCT06372132

• 68Ga-FAPI-46 versus 18F-FDG PET imaging in ER-positive breast cancer

  This test compares whether 68Ga-FAPI-46 PET scans find more cancer spread than standard 18F-FDG PET scans in people with ER-positive breast cancer who need staging.

  Recruiting Phase 2 Maastricht University Medical Center · Maastricht · NCT06335069

• Understanding reproductive counseling for patients with skin genetic disorders

  This study is trying to understand how people with skin genetic disorders and their partners make decisions about having children, while also looking at what doctors know and think about these choices.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT06330350

• Preoperative lifestyle intervention for breast cancer patients

  This study is testing a new program that combines exercise and nutrition to see if it helps breast cancer patients feel stronger and healthier before their surgery.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT06266312

• Understanding healthcare use in liver cirrhosis patients

  This study looks at how people with liver cirrhosis use healthcare services to better understand their needs and experiences.

  Recruiting at 2 sites Maastricht University Medical Center · Apeldoorn, Gelderland and 1 other locations · NCT06150482

• Comparing lymphaticovenous anastomosis to sham surgery for cancer-related lymphedema

  This study is testing if a new surgery for cancer-related lymphedema can help people feel better compared to a fake surgery.

  Recruiting at 3 sites Maastricht University Medical Center · Nijmegen, Gelderland and 2 other locations · NCT06082349

• Improving preoperative care for pancreatic surgery patients

  This study is testing a new health program to see if it helps patients get stronger and recover faster after pancreatic surgery.

  Recruiting at 13 sites Maastricht University Medical Center · 's-Hertogenbosch and 12 other locations · NCT05851534

• Differentiating and treating cystic lesions in the anterior mediastinum

  This study is trying to find better ways to identify and treat different types of cysts in the chest area for patients who have them.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT05839678

• OPTIMISE — safer steroid plans after DMEK cornea transplant

  This study tests whether using a milder steroid eye drop plan or stopping steroids earlier after DMEK can still prevent graft rejection while reducing the risk of high eye pressure in adults receiving corneal transplants.

  Recruiting at 6 sites Phase 4 Maastricht University Medical Center · Apeldoorn, Gelderland and 7 other locations · NCT05716945

• Exploring biomarkers to improve treatment for metastatic colorectal cancer

  This study is testing if certain biological markers can help doctors tailor treatment for people with advanced colorectal cancer to improve their response to medication and reduce side effects.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT05655780

• Using fMRI-neurofeedback to treat depression

  This study is testing if adding brain training using fMRI-neurofeedback to regular treatment can help adults with depression feel better compared to just getting standard care.

  Recruiting at 3 sites Maastricht University Medical Center · Maastricht and 2 other locations · NCT05640089

• Investigating cardiovascular risks in women after complicated pregnancies

  This study looks at how having high blood pressure during pregnancy might affect women's heart health later on and whether certain blood tests can help predict their risk for heart problems.

  Recruiting Maastricht University Medical Center · Maastricht · NCT05500989

• Evaluating oral hedgehog inhibitors for treating basal cell carcinoma in the Netherlands

  This study is testing if two oral medications, vismodegib and sonidegib, can help people with advanced basal cell carcinoma or Gorlin syndrome feel better and improve their condition.

  Recruiting at 7 sites Maastricht University Medical Center · Nijmegen, Gelderland and 7 other locations · NCT05463757

• Comparing medical grade honey to Fluconazole for treating recurrent vaginal yeast infections

  This study is testing whether a special medical grade honey can work as well as Fluconazole to treat women with recurring vaginal yeast infections.

  Recruiting at 2 sites Phase 3 Maastricht University Medical Center · Heerlen and 1 other locations · NCT05367089

• Registry for monitoring heart conditions

  This study is collecting health information from people with heart symptoms to see if it can help doctors catch heart problems earlier and understand them better.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT04976348

• Testing CP-506 for treating advanced solid tumors

  This study is testing a new drug called CP-506 to see if it can help people with advanced solid tumors, especially those with specific DNA repair issues, by trying it alone and with other treatments.

  Recruiting at 2 sites Phase 1/2 Maastricht University Medical Center · Brussels and 4 other locations · NCT04954599

• Examining complement-related thrombotic microangiopathy that injures the blood vessel lining

  This project will test whether a new endothelial cell-based blood test can detect complement overactivation as the cause of thrombotic microangiopathy in adults with acute kidney injury and TMA.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT04745195

• Less invasive axillary treatment for breast cancer after chemotherapy

  This study tests if a less invasive way to treat breast cancer after chemotherapy can keep women safe and improve their quality of life compared to more invasive methods.

  Recruiting at 35 sites Maastricht University Medical Center · 's-Hertogenbosch and 34 other locations · NCT04486495

• Using plant stanol esters to reduce asthma symptoms

  This study is testing if eating soft chews with plant stanol esters can help people with allergic asthma feel better by changing how their immune system works.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT03983603

• Non-invasive blood test to detect tumor DNA in cancer patients.

  This project will try to detect tumor DNA in blood from adults newly diagnosed with breast, colorectal, non-small cell lung cancer, or anaplastic glioblastoma before they start treatment.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT03019471

• Registry for patients with deep venous obstructions

  This study collects information from patients with deep vein blockages who are getting treated with a specific procedure to see how well it works and if it's safe.

  Recruiting Maastricht University Medical Center · Maastricht · NCT02650453

• Cohort of obese patients with nonalcoholic fatty liver disease

  This study is trying to find out what causes some obese people with fatty liver disease to develop a more serious condition and to see if there are easier ways to diagnose it.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT02422238

• Using blood biomarkers to assess heart disease risk

  This study is trying to see if certain blood markers can help identify people at risk for heart disease and serious heart problems when they have a routine heart scan.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT02381301

• Collection of genetic material and data for future research

  This study is collecting genetic samples and health information from new patients to help researchers learn more about genetic diseases and find new treatments.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT02266615

• Evaluating vascular function in children with different weight categories

  This study looks at how weight affects blood vessel health in kids aged 6 to 18 by comparing lean and overweight children.

  Recruiting Maastricht University Medical Center · Maastricht, Limburg · NCT02113644

Quick answers

How many clinical trials run by Maastricht University Medical Center are recruiting right now?

53, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 14 countries. The most sites are in Netherlands (49 trials), Belgium (5 trials), Germany (2 trials), Spain (2 trials), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 3: 1, Phase 1/2: 1, Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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