Measure total energy use in ICU patients with a doubly labeled water test.
Official title: Measuring Total Energy Expenditure in Critically Ill Patients Using the Doubly Labelled Water Method
Run by Maastricht University Medical Center · NCT07256340 · Data updated 2026-11-12
This will test whether the doubly labeled water method can accurately measure daily calorie needs in adults who are critically ill in the ICU.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Maastricht University Medical Center Academic / other |
| Locations | 1 site (Hasselt, Limburg) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | July 2026 |
| Study ends | September 2026 |
| Registry record updated | December 10, 2025 |
| Trial ID | NCT07256340 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age ≥18) admitted to the ICU at Jessa Hospital with an expected ICU stay of five days or more and not receiving dialysis are the intended participants.
✕Probably not a fit
Patients on dialysis, those expected to be in the ICU for fewer than five days, or people admitted to other hospitals are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study applies the doubly labeled water (DLW) technique to directly measure total energy expenditure (TEE) in adult intensive care patients. Enrolled patients at Jessa Hospital will receive DLW dosing and have metabolic measurements collected over several days to capture true energy use during critical illness. Measured TEE will be compared against common predictive equations and, where available, indirect calorimetry. Findings aim to determine whether DLW can improve precision in prescribing nutrition for ICU patients.
Why it matters
Potential benefit: If successful, this could enable more accurate, personalized nutrition plans in the ICU that reduce malnutrition and improve recovery.
How similar studies have gone: DLW is the gold-standard for measuring TEE in ambulatory populations and has produced accurate results in some critically ill cohorts, but it is less commonly tested and implemented in routine ICU nutrition management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admitted to the ICU of Jessa Hospital * Male and female sexes * Age: \> 18 years old * Expected ICU stay of 5 days or more Exclusion Criteria: * Dialysis
Where it's running
-
Jessa Hospital Campus Virga Jesse
Hasselt, Limburg, Belgium Recruiting
Study contacts
- Study coordinator: Michèlle Hendriks
- Email: michelle.hendriks@maastrichtuniversity.nl
- Phone: +31 43 388 1184
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.