Observing mechanical complications after heart attacks
Official title: Mechanical Complications of Acute Myocardial Infarction: a Multicenter Prospective Observational Study
Run by Maastricht University Medical Center · NCT06676345 · Data updated 2026-11-12
This study is testing different treatment options for patients who have serious heart problems after a heart attack to see which ones work best.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 800 (estimated) |
| Sponsor | Maastricht University Medical Center Academic / other |
| Locations | 1 site (Varese) |
| Status | Recruiting |
| Started | January 1, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2032 |
| Registry record updated | May 11, 2025 |
| Trial ID | NCT06676345 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients diagnosed with post-infarction mechanical complications, regardless of the treatment they receive.
✕Probably not a fit
Patients with cardiac rupture not related to acute myocardial infarction will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to collect prospective data on patients who experience mechanical complications following acute myocardial infarction, such as ventricular septal defect and papillary muscle rupture. By focusing on both surgical and percutaneous treatment approaches, the study seeks to clarify the most effective management strategies for these serious conditions. It addresses limitations found in previous retrospective studies, aiming for more accurate and reliable outcomes. The research will involve multiple centers to gather a diverse patient population and enhance the generalizability of the findings.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols and outcomes for patients suffering from mechanical complications after heart attacks.
How similar studies have gone: While previous studies have explored similar complications, this prospective approach is designed to address gaps in data from earlier retrospective analyses, making it a novel effort.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * all the patients diagnosed with post-infarction mechanical complications, independently from the treatment assigned Exclusion Criteria: * patients with cardiac rupture not acute myocardial infarction related
Where it's running
-
ASST dei Sette Laghi
Varese, Italy Recruiting
Study contacts
- Study coordinator: Matteo Matteucci, MD, PhD
- Email: matteomatteucci87@gmail.com
- Phone: +39.3493556001
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
GORE MBA Arch Endoprosthesis Early Feasibility Study
This study tests the safety of the MBA device in people with arch-related thoracic aortic diseases to see if it can be used safely in real-world settings.
-
Real-world use of WallabyPhenox flow-diversion and stent devices for brain aneurysms and vascular injuries
This registry tracks whether WallabyPhenox flow-diverters, stents, and related implants work well and are safe for people treated for brain aneurysms, dissections, pseudoaneurysms, perforations, or related vascular problems.
-
Endovascular repair for ascending aortic conditions
This study is testing if a special stent can safely repair problems in the ascending aorta for patients with conditions like aortic dissection and pseudoaneurysms.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.