Observing mechanical complications after heart attacks
Mechanical Complications of Acute Myocardial Infarction: a Multicenter Prospective Observational Study
Maastricht University Medical Center · NCT06676345
This study is testing different treatment options for patients who have serious heart problems after a heart attack to see which ones work best.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 800 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Maastricht University Medical Center (other) |
| Locations | 1 site (Varese) |
| Trial ID | NCT06676345 on ClinicalTrials.gov |
What this trial studies
This study aims to collect prospective data on patients who experience mechanical complications following acute myocardial infarction, such as ventricular septal defect and papillary muscle rupture. By focusing on both surgical and percutaneous treatment approaches, the study seeks to clarify the most effective management strategies for these serious conditions. It addresses limitations found in previous retrospective studies, aiming for more accurate and reliable outcomes. The research will involve multiple centers to gather a diverse patient population and enhance the generalizability of the findings.
Who should consider this trial
Good fit: Ideal candidates include patients diagnosed with post-infarction mechanical complications, regardless of the treatment they receive.
Not a fit: Patients with cardiac rupture not related to acute myocardial infarction will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols and outcomes for patients suffering from mechanical complications after heart attacks.
How similar studies have performed: While previous studies have explored similar complications, this prospective approach is designed to address gaps in data from earlier retrospective analyses, making it a novel effort.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all the patients diagnosed with post-infarction mechanical complications, independently from the treatment assigned Exclusion Criteria: * patients with cardiac rupture not acute myocardial infarction related
Where this trial is running
Varese
- ASST dei Sette Laghi — Varese, Italy (RECRUITING)
Study contacts
- Study coordinator: Matteo Matteucci, MD, PhD
- Email: matteomatteucci87@gmail.com
- Phone: +39.3493556001
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ventricular Septal Defect, Papillary Muscle Rupture, Cardiac Rupture, Pseudoaneurysm