Clinical trial Recruiting at 1 site Interventional Ages 18 to 35

Whole-food beef protein and amino acid oxidation in young adults

Official title: Amino Acid Oxidation of Whole-Food Protein: a Dose-Response Crossover Trial in Young Adults

Run by Maastricht University Medical Center · NCT07547176 · Data updated 2026-11-12

This test will see how three dinner doses of minced beef affect 24-hour amino acid oxidation in healthy 18–35-year-olds.

More Protein Metabolism trials

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexAll
Enrollment20 (estimated)
SponsorMaastricht University Medical Center
Academic / other
Locations1 site (Maastricht, Limburg)
StatusRecruiting
StartedNovember 1, 2025
Main results expectedMarch 1, 2027
Study endsMarch 1, 2027
Registry record updatedApril 23, 2026
Trial IDNCT07547176 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy males and females aged 18–35 with BMI 18.5–30 kg/m2 who are recreationally active, consume beef, and are not taking medications that affect protein metabolism are ideal candidates.

Probably not a fit

People who are vegan or vegetarian, smokers, pregnant women, those with diagnosed GI disorders, or those taking medications that affect protein metabolism are unlikely to benefit from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In a randomized crossover design, 20 healthy young adults (ages 18–35) consume dinners providing 0.32, 0.74, and 1.32 g protein·kg body mass−1 (equivalent to 1, 2, and 4 minced beef patties) across three separate experimental visits. Amino acid oxidation from the ingested protein is measured over a 24-hour period after each meal. Participants serve as their own controls so dose-response relationships can be compared within individuals. The study focuses on whole-food protein (minced beef) rather than isolated protein supplements.

Why it matters

Potential benefit: If successful, the results could help define practical whole-food protein portions that reduce amino acid waste and inform dietary protein recommendations for young adults.

How similar studies have gone: Prior dose-response studies using isolated proteins and mixed meals have shown dose-dependent amino acid oxidation, but comparable data using whole-food beef are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged between 18-35 years
* BMI between 18.5-30 kg/m2
* Healthy, recreationally active (exercise at least once per two weeks and a maximum of four days per week)
* No physical limitations (i.e., able to perform all activities associated with daily living independently)

Exclusion Criteria:

* Smoking
* Vegan, vegetarian, or does not consume beef protein
* Diagnosed musculoskeletal disorders
* Use of any medications known to affect protein metabolism (i.e., corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications)
* Chronic use of gastric acid-suppressing medication or anti-coagulants
* Unstable weight over the last three months
* Diagnosed GI tract disorders or diseases
* Blood donation in the past 2 months
* Females: pregnancy

Where it's running

  • Maastricht University Medical Centre+
    Maastricht, Limburg, Netherlands
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.