Comparing G-POEM and PEG-J treatments for gastroparesis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial evaluates the effectiveness of two treatment options, G-POEM and PEG-J, for patients suffering from refractory gastroparesis. It involves a randomized, non-blinded controlled design with two groups: one receiving G-POEM and the other receiving PEG-J. Treatment success will be assessed using the Gastroparesis Cardinal Symptom Index (GCSI) at baseline and six months post-intervention, with a potential crossover after the follow-up period. The study aims to enroll 50 patients who have not responded to standard dietary and pharmacological treatments.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with GP
* 13C octanoic acid test or gastric scintigraphy (minimal 4-hour measurement) within the past twelve months
* 18 years old

Exclusion Criteria:

* \< 18 years old
* Medical history of stomach surgery in which resection of antrum and/ or pylorus took place
* Medical history of surgical or laparoscopic pyloromyotomy
* Gastric bypass
* Current opioid use
* Pregnancy

Where it's running

• Maastricht University Medical Center
  Maastricht, Zuid-Limburg, Netherlands Recruiting

Study contacts

• Study coordinator: Kim Sweerts
• Email: kim.sweerts@maastrichtuniversity.nl
• Phone: +31 88 388 7298

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.