Clinical trial Recruiting at 1 site Interventional Ages 18 to 35

Effects of Walking Breaks on Cognitive Function and Glucose Metabolism

Official title: Effects of Sitting Interruption Frequency on Cognitive Function and Glucose Metabolism: A Randomized, Controlled Cross-over Study Involving Young Sedentary Adults

Run by Maastricht University Medical Center · NCT06700187 · Data updated 2026-11-12

This study is testing if taking walking breaks during long periods of sitting can help young adults think better and improve their blood sugar levels.

Quick facts

Study typeInterventional
Ages18 Years to 35 Years
SexAll
Enrollment33 (estimated)
SponsorMaastricht University Medical Center
Academic / other
Locations1 site (Maastricht)
StatusRecruiting
StartedOctober 3, 2024
Main results expectedMarch 27, 2026
Study endsMarch 27, 2026
Registry record updatedJanuary 14, 2026
Trial IDNCT06700187 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are sedentary men and women aged 18-35 with a BMI between 18.5-24.9 who sit for at least 9 hours a day and exercise less than 2-3 times a week.

Probably not a fit

Patients who are physically active, sit for less than 9 hours a day, or have conditions affecting glucose metabolism may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how interrupting prolonged sitting with walking breaks affects cognitive function and glucose metabolism in young sedentary adults aged 18-35. Participants will engage in different frequencies of physical activity bouts during four 6-hour laboratory visits. The research aims to determine if varying the frequency of these breaks can lead to improvements in cognitive performance and metabolic health. The study is designed as a randomized controlled trial to provide robust evidence on the impact of sedentary behavior interventions.

Why it matters

Potential benefit: If successful, this study could lead to effective strategies for improving cognitive function and metabolic health in sedentary young adults.

How similar studies have gone: While the effects of sedentary behavior on health have been studied, this specific approach of varying walking break frequencies in young adults is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Men and women aged 18-35 years;
* BMI between 18.5-24.9 kg/m2;
* SB, i.e. sitting for an average of at least 9 hours per day;
* Physically inactive, i.e. engaging in exercise for less than 2 to 3 times per week;
* Stable body weight (weight gain or loss \< 3 kg in the past three months);
* Willingness to engage in four 6-hour laboratory visits;
* No difficult cannulation.

Exclusion Criteria:

* Not sedentary, i.e. sitting for less than an average of 9 hours per day;
* Physically active, i.e. engaging in exercise for more than 3 times a week;
* Abuse of drugs;
* Use medication to treat BP, lipid, or glucose metabolism;
* Pregnant females.

Where it's running

  • Nutrition and movement science
    Maastricht, Netherlands
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.