Effects of Walking Breaks on Cognitive Function and Glucose Metabolism
Official title: Effects of Sitting Interruption Frequency on Cognitive Function and Glucose Metabolism: A Randomized, Controlled Cross-over Study Involving Young Sedentary Adults
Run by Maastricht University Medical Center · NCT06700187 · Data updated 2026-11-12
This study is testing if taking walking breaks during long periods of sitting can help young adults think better and improve their blood sugar levels.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 35 Years |
| Sex | All |
| Enrollment | 33 (estimated) |
| Sponsor | Maastricht University Medical Center Academic / other |
| Locations | 1 site (Maastricht) |
| Status | Recruiting |
| Started | October 3, 2024 |
| Main results expected | March 27, 2026 |
| Study ends | March 27, 2026 |
| Registry record updated | January 14, 2026 |
| Trial ID | NCT06700187 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are sedentary men and women aged 18-35 with a BMI between 18.5-24.9 who sit for at least 9 hours a day and exercise less than 2-3 times a week.
✕Probably not a fit
Patients who are physically active, sit for less than 9 hours a day, or have conditions affecting glucose metabolism may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates how interrupting prolonged sitting with walking breaks affects cognitive function and glucose metabolism in young sedentary adults aged 18-35. Participants will engage in different frequencies of physical activity bouts during four 6-hour laboratory visits. The research aims to determine if varying the frequency of these breaks can lead to improvements in cognitive performance and metabolic health. The study is designed as a randomized controlled trial to provide robust evidence on the impact of sedentary behavior interventions.
Why it matters
Potential benefit: If successful, this study could lead to effective strategies for improving cognitive function and metabolic health in sedentary young adults.
How similar studies have gone: While the effects of sedentary behavior on health have been studied, this specific approach of varying walking break frequencies in young adults is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Men and women aged 18-35 years; * BMI between 18.5-24.9 kg/m2; * SB, i.e. sitting for an average of at least 9 hours per day; * Physically inactive, i.e. engaging in exercise for less than 2 to 3 times per week; * Stable body weight (weight gain or loss \< 3 kg in the past three months); * Willingness to engage in four 6-hour laboratory visits; * No difficult cannulation. Exclusion Criteria: * Not sedentary, i.e. sitting for less than an average of 9 hours per day; * Physically active, i.e. engaging in exercise for more than 3 times a week; * Abuse of drugs; * Use medication to treat BP, lipid, or glucose metabolism; * Pregnant females.
Where it's running
-
Nutrition and movement science
Maastricht, Netherlands Recruiting
Study contacts
- Study coordinator: Renyan Ma
- Email: renyan.ma@maastrichtuniversity.nl
- Phone: +31 883887804
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.