Sponsor or institution
Clinical trials and research at James J Peters VA Medical Center
As of November 12, 2026, Find a Trial lists 64 NIH-funded research projects at this institution. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 64NIH research projects
NIH-funded research (newest 40 of 64)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
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Immune system changes in Gulf War Veterans Illnesses and potential treatments
This NIH grant aims to study how immune and inflammatory processes contribute to Gulf War Veterans Illnesses and to develop new treatment approaches.
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Understanding immune dysfunction and social stress in veterans with depression
A study in U.S. veterans with major depressive disorder looks at how stress-related immune changes may be linked to depression and heart health.
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Maximizing Home Health Aide Support for Veterans and their Caregivers
A VA-focused project to improve access and stability of home health aide services for older veterans and reduce caregiver burden.
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How VA Medical Foster Homes may cut costs for long-term care
A VA-funded project is examining whether Medical Foster Homes with trained caregivers can provide a cheaper community-based alternative to nursing homes for aging Veterans who receive home-based primary care.
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Predicting lower-leg fracture risk during exoskeleton-assisted walking after spinal cord injury
This project uses scans and movement data to predict which people with recent spinal cord injuries might have a higher risk of leg fractures when walking with a robotic exoskeleton.
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Blood DNA changes after repeated blast exposure and poor sleep
This project looks at chemical marks on blood DNA in military and law enforcement personnel who had repeated blast exposures and sleep problems to learn how those changes connect to brain injury symptoms.
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Understanding Parkinson-like Symptoms After Traumatic Brain Injury in Veterans
A study explores how brain injuries in veterans relate to later Parkinson-like symptoms, aiming to identify clinical features and biomarkers that could guide future care.
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Membrane channel blockers to protect the brain after mild blast injury
Testing whether drugs that block certain membrane channels can reduce long-term inflammation and thinking or mood problems after mild blast-related brain injury in Veterans.
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Effects of spinal cord stimulation on autonomic function in veterans with spinal cord injury
This study is looking at how a special treatment that stimulates the spinal cord might help veterans with spinal cord injuries feel better by improving their body's automatic functions, like blood pressure and temperature control, especially for those with more severe injuries.
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How COVID-19 changed healthcare for veterans with spinal cord injuries
This project looks at how the COVID-19 pandemic disrupted health services and affected outcomes for veterans with spinal cord injuries and disorders.
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Romosozumab to Improve Bone Density and Structure in Chronic SCI
A study tests a dual drug approach to strengthen bones in adults with long-standing spinal cord injury to help prevent fractures and improve daily living.
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Integrating immune and brain reward biology in veterans with mood problems
A study in veterans with mood disorders looks at how the immune system and brain reward circuits may work together to drive depression and suicide risk.
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Spinal and brain stimulation to boost hand and arm movement in ALS
This project pairs mild spinal-cord and brain stimulation to help people with ALS strengthen hand and arm movements.
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Improving emotional awareness to reduce suicide risk in veterans
This study is all about helping veterans with serious mental health challenges become more aware of their emotions, so they can better handle social situations and make safer choices, ultimately aiming to reduce the risk of suicide.
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How the mGluR2 brain receptor may cause long-term problems after blast-related mild TBI
This project tests whether changes in a brain receptor called mGluR2 help explain long-lasting thinking, memory, and emotional problems after blast-related mild traumatic brain injury in veterans.
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Blocking Siglec-15 to help bones heal and stay strong after spinal cord injury
A treatment that blocks Siglec-15 aims to strengthen bones and improve fracture healing for people living with chronic spinal cord injury.
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Improving a powered exoskeleton to help veterans with knee osteoarthritis
This study is looking at how to make a special exoskeleton better for veterans with knee osteoarthritis, so they can move more easily and feel less pain, while also seeing how it stacks up against regular knee braces.
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Large-scale look at how genes and epigenetics relate to mental illness across many traits
A large study using a huge veteran biobank to understand how genetic and epigenetic factors connect with serious mental illnesses in diverse people.
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Dynamic Regulation of Erythropoietin Gene Expression in Mammals
Aims to understand how the body normally controls erythropoietin (Epo) production to improve anemia treatment and safety.
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Understanding how social stress affects immune function and depression in veterans
This study is looking at how problems with the immune system might be connected to depression in veterans who have faced social stress, especially those who served in Afghanistan and Iraq, and it hopes to find new ways to help improve their treatment for depression and PTSD.
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CH25H and 25‑hydroxycholesterol as potential protectors of diabetic kidneys
This work looks at whether a cholesterol-processing enzyme (CH25H) and its product 25‑HC protect the tiny blood vessels in kidneys damaged by diabetes.
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Hospital-level care at home for Veterans
This project explores bringing hospital-level care into Veterans' homes and whether VA sites are ready to offer it.
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Creating a treatment to help veterans recover after a suicide attempt
This study is working on a new type of therapy designed to help veterans who have recently gone through a tough time after a suicide attempt, focusing on building hope and confidence to support their recovery and mental health.
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Creating a cooling vest to help people with spinal cord injuries manage body temperature
This study is testing a new cooling vest for people with spinal cord injuries above T6 to help them stay cool and comfortable, especially in warm weather, so they can avoid overheating and enjoy a better quality of life.
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Using exoskeletons and spinal stimulation to improve bone strength in people with spinal cord injuries
This study is looking at how using special walking devices and gentle electrical stimulation can help strengthen bones in people with spinal cord injuries, aiming to prevent bone loss and improve their overall health and well-being.
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Finding genes linked to suicide risk in Veterans using brain tissue and VA health data
This work looks for genetic and brain-cell changes tied to suicide risk in Veterans to help identify those who may need extra support.
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How medical foster home coordinators affect care costs for Veterans
This project looks at whether the experience and effort of coordinators who run Medical Foster Homes can lower long-term care costs for Veterans compared with nursing home care.
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Helping Veterans Reduce Suicidal Thoughts with Brain Training
This project helps Veterans learn to control brain activity linked to repetitive negative thinking that can lead to suicidal thoughts.
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How the CCL5/CCR5 immune pathway affects depression differently in women and men
This project looks at whether an immune signal called CCL5 and its receptor CCR5 affect depression differently in women and men and whether targeting them could help.
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Managing medications at home through pharmacy telehealth visits
This study is looking at how virtual check-ins with pharmacists can help older adults who take multiple medications stay safe and healthy by making sure their prescriptions work well together and that they understand how to take them properly.
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Analyzing genetic and epigenetic factors in serious mental illness
This study is looking at how our genes might affect serious mental health issues by using information from over 650,000 veterans, and it hopes to find ways to create more personalized treatments that could help people manage their mental health better.
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Understanding how antibodies respond to COVID-19
This study is looking at how our bodies fight the COVID-19 virus by checking the antibodies made after vaccination or infection, especially in older veterans, to help improve vaccines and treatments.
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Exploring how blast exposure affects DNA and sleep in veterans
This study is looking at how exposure to blasts during military training might affect veterans' DNA and their sleep, and it's for veterans who have experienced mild traumatic brain injuries and want to help us understand these long-term effects better.
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Using Romosozumab to Improve Bone Health in People with Chronic Spinal Cord Injury
This study is looking at how a new treatment with Romosozumab can help people with chronic spinal cord injuries build stronger bones and reduce the risk of fractures, making it easier for them to stay active and enjoy daily life.
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Investigating immune responses in Gulf War Veterans' Illnesses
This study is looking into how the immune system and inflammation are linked to the symptoms Gulf War Veterans face, like memory problems and mood issues, to help find better treatments for their health challenges.
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Understanding Parkinsonism in Veterans with Brain Injuries
This study is looking at how brain injuries from military service can affect veterans in the long run, especially in causing symptoms similar to Parkinson's disease, and it aims to help us understand these effects better so we can improve treatment options for those affected.
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Improving bone health and healing after spinal cord injury
This study is testing a new treatment to help people with chronic spinal cord injuries keep their bones strong and heal better after fractures by using a special antibody that targets specific bone cells, and it aims to make life easier and safer for those affected.
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Investigating the neurobiology of schizophrenia and suicidal behavior in Veterans
This study is looking at how brain activity relates to impulsive behavior in Veterans with schizophrenia, especially those at risk for suicide, to find new ways to help them feel better and stay safe.
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Investigating the biological causes of neurological disorders in veterans
This study is looking into how certain changes in our genes might be linked to brain and nerve disorders, like ALS, that many veterans face, with the hope of finding new and better treatments for those who are struggling with these conditions.
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Investigating the immune response to HIV and COVID-19
This study is looking at how our immune system fights off HIV and the coronavirus to find new ways to help people stay healthy, and it's being done by a friendly team at the James J. Peters VA Medical Center.
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