NIH-funded research NIH-funded research

Effects of spinal cord stimulation on autonomic function in veterans with spinal cord injury

Official title: Autonomic Effects of Transcutaneous Spinal Cord Stimulation in Veterans with SCI

Funded at James J Peters VA Medical Center · NIH-11334099 · Data updated 2026-11-12

This study is looking at how a special treatment that stimulates the spinal cord might help veterans with spinal cord injuries feel better by improving their body's automatic functions, like blood pressure and temperature control, especially for those with more severe injuries.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJames J Peters VA Medical Center
NIH-funded
Lab location1 site (Bronx, United States)
Project startApril 1, 2023
Project endSeptember 30, 2025
Funding year2025
NIH project number5I21RX004373-03
Project IDNIH-11334099 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans with spinal cord injuries, particularly those with injuries at or above the T6 level who experience autonomic dysfunction.

Less likely to help

Patients with spinal cord injuries below the T6 level or those without significant autonomic dysfunction may not benefit from this research.

What this research studies

This research investigates how transcutaneous spinal cord stimulation can activate neural circuits in veterans with spinal cord injury (SCI) to improve autonomic nervous system (ANS) function. The study focuses on individuals who experience significant ANS dysfunction, particularly those with injuries at or above the T6 vertebra. By stimulating the spinal cord, the research aims to enhance neural plasticity, potentially leading to better regulation of blood pressure, temperature, and overall autonomic balance. Participants will be monitored for improvements in symptoms related to blood pressure instability and other autonomic complications.

Why it matters

Potential benefit: If successful, this research could lead to improved management of autonomic dysfunction, enhancing the quality of life for veterans with spinal cord injuries.

How similar studies have gone: Previous research has shown promising results with spinal cord stimulation techniques in improving autonomic function, suggesting potential for success in this approach.

Where this research is happening

  • James J Peters VA Medical Center
    Bronx, United States
    Active

Researchers

  • Principal investigator: Wecht, Jill M. — James J Peters VA Medical Center
  • Study coordinator: Wecht, Jill M.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.