NIH-funded research NIH-funded research

Helping Veterans Reduce Suicidal Thoughts with Brain Training

Official title: Reducing Suicide-Specific Rumination in Veterans using Real-time Functional Magnetic Resonance Imaging Neurofeedback

Funded at James J Peters VA Medical Center · NIH-11132585 · Data updated 2026-11-12

This project helps Veterans learn to control brain activity linked to repetitive negative thinking that can lead to suicidal thoughts.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionJames J Peters VA Medical Center
NIH-funded
Lab location1 site (Bronx, United States)
Project startJuly 1, 2024
Project endJune 30, 2026
Funding year2025
NIH project number5I21RX005132-02
Project IDNIH-11132585 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are Veterans aged 21 and older who experience persistent self-critical rumination and suicidal thoughts.

Less likely to help

Patients who do not experience rumination or suicidal ideation, or who are unable to participate in fMRI sessions, may not receive direct benefit from this specific intervention.

What this research studies

Many Veterans experience suicidal thoughts, and a common factor is getting stuck in repetitive, self-critical thinking patterns called rumination. This project uses a special type of brain imaging called real-time fMRI neurofeedback to show Veterans their own brain activity as it happens. The goal is to teach them how to adjust this activity in specific brain areas involved in rumination. By learning to change these brain patterns, Veterans may find it easier to interrupt negative thoughts and reduce their risk of suicide.

Why it matters

Potential benefit: If successful, this approach could offer a new way for Veterans to gain control over their thoughts and reduce the risk of suicide.

How similar studies have gone: While fMRI neurofeedback is a developing field, previous research suggests that targeting specific brain networks can help manage conditions like depression and anxiety, making this a promising, though still novel, application for suicide prevention.

Where this research is happening

  • James J Peters VA Medical Center
    Bronx, United States
    Active

Researchers

  • Principal investigator: Szeszko, Philip R — James J Peters VA Medical Center
  • Study coordinator: Szeszko, Philip R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.