Exploring how blast exposure affects DNA and sleep in veterans
Official title: Identifying DNA Methylation Alterations of Chronic Effects Of Blast and Disturbed Sleep
Funded at James J Peters VA Medical Center · NIH-11092808 · Data updated 2026-11-12
This study is looking at how exposure to blasts during military training might affect veterans' DNA and their sleep, and it's for veterans who have experienced mild traumatic brain injuries and want to help us understand these long-term effects better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James J Peters VA Medical Center NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | April 1, 2022 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| NIH project number | 5I01RX003818-04 |
| Project ID | NIH-11092808 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans who have experienced blast exposure during their service and are experiencing sleep disturbances or symptoms of mTBI.
✕Less likely to help
Patients who have not been exposed to blasts or do not exhibit symptoms related to traumatic brain injury may not benefit from this research.
What this research studies
This research investigates the long-term effects of blast exposure on DNA methylation and sleep disturbances in veterans. By analyzing blood samples from military personnel who have undergone operational blast training, the study aims to identify biological markers associated with chronic symptoms of mild traumatic brain injury (mTBI). The research utilizes advanced techniques to examine changes in DNA that may correlate with sleep issues and other related symptoms. Participants will contribute blood samples and provide information about their experiences and health conditions.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for veterans suffering from sleep disturbances and other symptoms related to blast exposure.
How similar studies have gone: Previous research has shown promising results in understanding the biological impacts of blast exposure, suggesting that this approach could yield valuable insights.
Where this research is happening
-
James J Peters VA Medical Center
Bronx, United States Active
Researchers
- Principal investigator: Haghighi, Fatemeh G — James J Peters VA Medical Center
- Study coordinator: Haghighi, Fatemeh G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.