Investigating immune responses in Gulf War Veterans' Illnesses
Official title: CMA: Immune/inflammatory priming in exacerbating responses to GWVI stressors: implications for GWVI treatments
Funded at James J Peters VA Medical Center · NIH-11087453 · Data updated 2026-11-12
This study is looking into how the immune system and inflammation are linked to the symptoms Gulf War Veterans face, like memory problems and mood issues, to help find better treatments for their health challenges.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | James J Peters VA Medical Center NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project start | July 1, 2019 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| NIH project number | 5I01BX004583-06 |
| Project ID | NIH-11087453 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Gulf War Veterans experiencing symptoms related to Gulf War Veterans' Illnesses, such as cognitive impairment, fatigue, and mood disorders.
✕Less likely to help
Patients who are not Gulf War Veterans or do not exhibit symptoms related to Gulf War Veterans' Illnesses may not benefit from this research.
What this research studies
This research focuses on understanding how immune and inflammatory responses are affected in Gulf War Veterans who experience a range of symptoms such as cognitive impairment and mood disorders. By using experimental models, the research aims to identify the mechanisms behind these persistent immune responses triggered by exposure to specific toxins during deployment. The ultimate goal is to develop new therapeutic interventions that can alleviate the symptoms associated with Gulf War Veterans' Illnesses. Patients may benefit from insights that could lead to more effective treatments tailored to their unique health challenges.
Why it matters
Potential benefit: If successful, this research could lead to novel treatments that significantly improve the quality of life for Gulf War Veterans suffering from chronic health issues.
How similar studies have gone: Previous research has shown promise in understanding immune responses in similar populations, suggesting that this approach could yield valuable insights.
Where this research is happening
-
James J Peters VA Medical Center
Bronx, United States Active
Researchers
- Principal investigator: Pasinetti, Giulio Maria — James J Peters VA Medical Center
- Study coordinator: Pasinetti, Giulio Maria
Related research
Other NIH-funded projects on the same topics.
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Immune system changes in Gulf War Veterans Illnesses and potential treatments
This NIH grant aims to study how immune and inflammatory processes contribute to Gulf War Veterans Illnesses and to develop new treatment approaches.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.